Advertorial – Lallemand Animal Nutrition
Protect the energy production by strengthening the sprinkler system and fewer fires will spread. Feeding Melofeed stimulates the body’s natural production of primary antioxidants — effectively increasing the number of sprinklers in each mitochondrial power plant.
By Lallemand Animal Nutrition
What Is Oxidative Stress?
Oxidative stress — a term often heard in discussions about health, welfare and well-being — goes beyond just free radicals and antioxidants. It’s a complex phenomenon that causes chaos in all cells of the animal body.
Production of reactive oxygen species (ROS) is a natural consequence of life. It arises within the cells of animals as a byproduct of metabolic processes, especially in the mitochondria, where energy is produced. Normally, the body has a finely tuned system to maintain a balance between ROS production and the action of antioxidants. Oxidative stress is the result of an imbalance between ROS and the body’s ability to counteract or neutralize their harmful effect with antioxidants. When stressors shift the balance, an imbalance can occur due to an overproduction of ROS or a depleted antioxidant system.
When Stressors Shift the Balance
Stressors, such as heat, pathogens, housing conditions and vaccination can induce oxidative stress in the animal’s body – a situation where the whole neighbourhood is burning.
WOULD YOU LIKE YOUR ANIMAL TO BE PROTECTED FROM THIS OVERWHELMING EXPERIENCE AND BOOST ITS IN-HOUSE PROTECTION SYSTEM?
Protect the energy production by strengthening the sprinkler system and fewer fires will spread. Feeding Melofeed stimulates the body’s natural production of primary antioxidants — effectively increasing the number of sprinklers in each mitochondrial power plant.
UNDER MELOFEED SUPPLEMENTATION
How to Measure “More Sprinklers”?
Western blot analysis makes it possible to see how many sprinklers the cells have actually installed.
By detecting proteins directly, this method shows whether key antioxidant enzymes are present in higher amounts. Tissue samples from different species (from rodents to farm and aquatic animals) were examined, covering organs such as heart, liver, muscle, and the reproductive tract.
In these analyses, Melofeed supplementation led to a consistent rise in the expression of the primary antioxidant enzymes SOD, CAT, and GPx. On average, levels were 25–30% higher, confirming that the cellular neighborhoods had indeed strengthened their sprinkler systems to better control the sparks of oxidative stress (Figure 1A, 1B and 1C).
References
1. Carillon et al. (2016): Diet supplementation with a specific melon concentrate improves oviduct antioxidant defenses and egg characteristics in laying hens. Poultry Science, 95: 1898-1904
2. Carillon et al. (2014). Endogenous antioxidant defense induction by melon superoxide dismutase reduces cardiac hypertrophy in spontaneously hypertensive rats. Molecular and Cellular Biochemistry, 386(1-2), 125-1341
3. Carillon et al. (2014). Curative Diet Supplementation with a Melon Superoxide Dismutase Reduces Adipose Tissue in Obese Hamsters by Improving Insulin Sensitivity. Molecular and Cellular Biochemistry, 386(1-2), 125-1341
4. Carillon et al. (2013). Cafeteria Diet Induces Obesity and Insulin Resistance Associated with Oxidative Stress but Not with Inflammation: Improvement by Dietary Supplementation with a Melon Superoxide Dismutase. Molecular and Cellular Biochemistry, 372(1-2), 35-44
5. Barbé et al. (2017): Stimulation of antioxidant defences and protection of the immune system in broilers supplemented with pelleted SOD-rich melon pulp concentrate. 21st European Symposium on Poultry Nutrition (Spain), poster
