ADM’s recent clinical trial shows that PRIOME® Metabolic Health, in both probiotic and heat-treated postbiotic forms, can support metabolic health in adult dogs. The study, published in the peer-reviewed journal Animals, highlights improvements in postprandial blood glucose during weight management.

As demand for functional pet supplements rises, ADM’s clinical study investigating the effects of PRIOME® Metabolic Health (PRIOME® MH), Bifidobacterium animalis subsp. lactis CECT 8145, in both probiotic and heat-treated postbiotic form in adult dogs, has been published by the prestigious scientific journal Animals. ADM notes that this publication adds another peer-reviewed canine clinical study to the company’s postbiotic evidence base and differentiates PRIOME® MH within the company’s growing pet biotics portfolio.
According to a statement, metabolic health is a major determinant of longevity and quality of life. In dogs, it encompasses factors such as weight management, blood glucose regulation, and hormonal balance. Although healthy dogs typically regulate blood sugar well, repeated glucose spikes—particularly in overweight or aging animals—can contribute to insulin resistance and other metabolic challenges.
Led by Dr. Sophie Nixon, Head of Clinical Research for Pet and Animal Wellbeing, this clinical trial has demonstrated the potential role of PRIOME® MH postbiotic to support canine metabolic health. The randomized, double-blind, placebo-controlled clinical study was conducted in 45 healthy adult dogs, evaluating the impact of daily probiotic or postbiotic supplementation on markers of metabolic health during periods of induced weight gain and weight loss. During the weight-loss phase of the trial, dogs receiving PRIOME® MH demonstrated a significant reduction in postprandial blood glucose compared with dogs given placebo.
The company states that this trial strengthens the growing evidence for postbiotics in companion animal research, driving innovation in functional nutrition. These findings significantly advance the industry’s understanding of postbiotic applications for canine metabolic health – a health area that historically has been underserved by biotic ingredients.