Feed & Additive Magazine Issue 53 June 2025

June 2025 Year: 5 Issue: 53 Feed Additive INTERNATIONAL MAGAZINE FOR ANIMAL FEED & ADDITIVES INDUSTRY Dr. Yun-Mei Amy Lin, Anitox Bacterial and viral pathogens in animal feed Monika Leukert, Lallemand From ingredients to strategy: Rethinking antioxidant defense Christophe Derrien, IPIFF Insects: Europe’s circular protein revolution www.feedandadditive.com Bacterial Pathogen Risk and Management Global Animal Feed Proteins Market

Publisher Muhammed Akatay akatay@feedandadditive.com Responsible Manager Özlem Akatay ozlem@feedandadditive.com Editor-in-Chief Derya Yıldız derya@feedandadditive.com Editors Burak Varol Zeynep Demirkaya editor@feedandadditive.com Communication & Marketing Lisa Atakul marketing@feedandadditive.com Design Alper Kandemir graphic@feedandadditive.com Web Design Caner Cem Pulat web@threeplusmedia.com Circulation and Data Responsible Amine Şengün sm@threeplusmedia.com Ataturk St. Metropol Istanbul Ste. Block C1, No:376 Atasehir, Istanbul/TURKEY Phone: +90 850 220 5064 E-Mail: info@feedandadditive.com Web: www.feedandadditive.com Publication Type: Periodic (Monthly) EDITOR Dear Readers, In this issue of Feed & Additive Magazine, we focus on a persistent and often underestimated threat in the modern livestock industry: Bacterial pathogens. These microscopic and silent enemies pose a significant risk to animal welfare, leading to reduced feed intake, decreased production efficiency and growth rates, and increased mortality rates, along with many more significant effects. For example, pathogens such as Salmonella, E. coli, and Clostridium can pose very serious risks to human health through direct exposure or the food chain. Today, we have highly advanced solutions for monitoring and detecting pathogen risks. Early diagnosis of infections is much easier, and we have the ability to intervene in a timely manner. Therefore, the key at this point is the ability to recognize the signs of bacterial infections in animals and implement effective prevention strategies. There are many tools available to producers, ranging from improved hygiene and vaccination programs to controlled housing conditions, but their success depends on consistent implementation and awareness. Additionally, the growing role of feed additives and nutrition strategies in supporting immune function and combating bacterial threats should not be overlooked. In this issue, experts discuss how optimal feeding practices can reduce infection risks, increase resistance, and support long-term animal performance. Preventing bacterial pathogens is not just a health concern, it is a requirement for the sustainability of the livestock industry. I hope you enjoy reading this issue. Managing the Invisible Threat in Animal Production Derya YILDIZ © Three Plus Media | All rights reserved. Reproduction, in whole or in part, is prohibited without the written permission of the publisher. *DISCLAIMER: All views and ideas expressed in articles published in the magazine reflect the point of views of the author(s), not that of the Editor-in-Chief, Editors, Editorial Board or Publisher of Feed & Additive Magazine. The Editor-in-Chief, Editors, Editorial Board and Publisher assume no responsibility or liability in such cases. The publisher does not give any warranty and representation to the accuracy or completeness of the contents and data published in the magazine. All responsibility of the contents, articles and information published in the magazine belongs to the authors. The publisher and the authors cannot be held responsible for any damages resulting from the use of the whole or part of the content of the magazine. feedandadditive

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CON T E N T S 28 ISSUE FOCUS BACTERIAL PATHOGEN RISK AND MANAGEMENT 52 FROM INGREDIENTS TO STRATEGY: RETHINKING ANTIOXIDANT DEFENSE Monika Leukert, Lallemand Animal Nutrition ADVERTORIAL 40 THE ONGOING BATTLE WITH FOOD POISONING: A PRESSING PUBLIC HEALTH CONCERN Dr. Inge Heinzl, EW Nutrition 43 MANAGING THE SHIFT TO CAGE-FREE EGG PRODUCTION Dr. Harriet Walker, Alltech 46 ANTINUTRIENTS IN FEED AND THEIR EFFECTS ON IMMUNITY, PRODUCTIVITY AND HEALTH OF SWINE Dr. Jeru Abelilla-Mesina, dsm-firmenich 30 BACTERIAL AND VIRAL PATHOGENS IN ANIMAL FEED Dr. Yun-Mei Amy Lin, Anitox 35 FROM SALMONELLA TO SALMONELLOSIS: WHERE AND HOW TO STOP THE TRANSMISSION Stefan Alius, Agrifirm INTERVIEWS MARSAPET INTRODUCES VEGAN DOG FOOD WITH MICROBIAL PROTEIN Marcel Hoffmann & Bert Fuhrmann, Marsapet NAVIGATING THE PRESSING CHALLENGES IN THE ANIMAL NUTRITION AND HEALTH INDUSTRY Dr. Christos Antipatis, Cargill 55 58

CON T E N T S 69 TRADE UNCERTAINTY DRIVES FEED, ADDITIVES PRICES DROP IN EARLY 2025 Stefan Schmidinger, Kemiex TRADE TIDES 72 SUPPORTING DAIRY COWS DURING HEAT STRESS Anna-Lena Beckmann, Dostofarm 78 SHIELDING POULTRY PERFORMANCE FROM THE HEAT Dr. Stephanie Ladirat, Nuqo 75 NUTRITIONAL SUPPORT AND AWARENESS GROWING FAST IN MIDDLE EAST Rony Makdessi & Danielle Ayyash, UTRIX ARTICLES MARKET REPORT UNDERSTANDING FEED PROTEINS IN ANIMAL NUTRITION 82 Derya Yıldız, Feed & Additive Magazine UTRIX to expand production capacity and regional presence in Middle East 19 Miavit and Arctic Feed Ingredients partner for global aquaculture market 23 Latest Selko webinar highlights importance of GFLI’s branded directory 10 dsm-firmenich and Bureau Veritas sign MoU for sustainable animal protein 90 Novus experts to share insights on soybean efficiency and sustainability 94 Buchi acquires NeoSpectra platform for integrated NIR ecosystem 15 Kemin expands innovation in pet intestinal health 12 NEWS 62 ADVANCING POULTRY SUSTAINABILITY AND PERFORMANCE David Gonzalez Sanchez & Karen Bierinckx & Frederika Somers, Kemin Industries 66 INSECTS: EUROPE’S CIRCULAR PROTEIN REVOLUTION Christophe Derrien, IPIFF SUSTAINABILITY

6 FEED & ADDITIVE MAGAZINE June 2025 EFFAB is the voice of animal breeding and reproduction organisations and companies. From small, medium and global organisations, we cover a wide variety of actors breeding for conventional, outdoor and organic animal farmers aimed at improving the next generations of farm animals. With our sister platform (FABRE TP), also hosted by the EFFAB secretariat, we are a unique place where the private sector and scientific institutions are committed to advancing responsible and innovative animal breeding practices through scientific collaboration. EFFAB’s primary mission is to dialogue with European policymakers and stakeholders, to whom we provide science-based and practical information about the role of animal breeding and genetics in sustainable animal farming. Animal breeders are at the start of European food systems and respond to farming and societal challenges. Yet, breeding in general and animal breeding in particular take time, and the decisions on the direction of travel made today will impact animal farming in 10 years’ time. This direction of travel is often narrowed to improving feed efficiency and animal productivity. These characteristics or traits are the basic ones linked to farmers' profitability, and the communication focus historically was on those. Worth noting that feed efficiency is also an indirect way to reduce GHG, in both monogastrics and ruminants. However, in the past 20 years, thanks to better knowledge and technology developed in research institutions, animal breeders have been able to expand the breeding goals and traits in breeding programs to better animal health and welfare, a further reduction of environmental impact (CH4 and N2O) and a better use of resources. This wide approach is called balanced animal breeding, as it aims to make an equilibrated compromise between all the essential aspects of animal farming. The weight of the different elements will depend on the species, the breeds and the farming systems. To illustrate this evolution, EFFAB has developed Code EFABAR, which aims to showcase how breedTHE ROLE OF ANIMAL BREEDING IN SHAPING THE FUTURE OF ANIMAL FARMING Ana Granados Director at European Forum of Farm Animal Breeders — EFFAB LEAD ARTICLE Other traits Production Traits Improved animal health and welfare Better production and quality of the products 2000’s - Today 1970’s - 1980’s Better use of resources Preserving genetic diversity Ensured food security Reduction of environmental impact

FEED & ADDITIVE MAGAZINE 7 June 2025 ers nowadays implement all these elements in their breeding programmes. The sole objective is to contribute responsibly to improving the sustainability of all animal farming systems. EFFAB PARTICIPATING IN LIVESTOCK AND AQUACULTURE POLICY DISCUSSIONS Food production and farmers’ situation have been receiving well-deserved attention from EU policymakers since 2023. The Green Deal cannot work without considering competitiveness and the sector's resilience. Animal breeding is key to delivering solutions, and the upcoming strategies in the EU for livestock and aquaculture must look at those. EFFAB is proud to be part of the conversation in Brussels, mainly but not only. The contributions of our members —scientists, researchers, and the private sector— are essential to enhancing the sustainability, resilience, and efficiency of animal farming. Their expertise fuels innovation and ensures that animal agriculture evolves in harmony with societal expectations, environmental imperatives, and animal welfare standards. Having these conversations is not just important— it is essential. The vitality and the social and environmental preservation of rural and coastal areas rely on pre-farm activities, such as animal breeding. The benefits of balanced animal breeding programs are numerous: Healthier animals, reduced environmental footprint, improved productivity, and greater societal acceptance of animal agriculture. EFFAB links the activities of our members to policymakers and stands ready to support the development of a forward-looking animal farming strategy that reflects these values. This is summarised in the EFFAB vision for 2030. More policy-related topics in which we are involved range from animal health and welfare to technology use and data sharing. This concretely means that we actively raise practical and science-based points from the semen collection sector related to the EU Animal Health Law, to mention one example. For some years now, we have been involved in the legislative process around the animal welfare initiatives for legislation of the European Commission; since the EC requested to EFSA to publish scientific opinions on the welfare of several farm animal species until the final legislative text, in the case of the Animal Welfare during Transport proposal. It’s not about keeping the sector operating under potentially outdated rules; it’s about making sure that policymakers make decisions based on in-depth knowledge of the animal breeding and reproduction sector and what it offers. This is when our Code EFABAR is more relevant than ever. We recommend that this Code of Good Practices for Responsible and Balanced Breeding should be recognised as the EU standard when drafting new policy initiatives and legislation. This ensures that policymakers and stakeholders are up-to-date on breeding practices, as the code is renewed every 3 years. Building on what already exists is key to creating a smart policy landscape for breeding organisations and to allow them to make further progress. And further progress can only be achieved by investing in ambitious research and innovation frameworks for pre-farm gate activities, including animal breeding and genetics. We need animal breeding in the EU to maintain its position as a world leader while continuing to create more opportunities for international cooperation in research and regulatory developments. It’s not only about the private sector being competitive, it is also about research institutions continuing to educate and prepare a high-level next generation of breeders and other related scientists. This year, at the EAAP conference in Innsbruck, we will host a challenge session on Wednesday, August 27, on the future of the European animal breeding sector from the academia and private sector perspectives. You are welcome to join us. EFFAB is also part of the European Livestock Voice and other platforms, as EPRUMA, which we have highly promoted to enhance communication around the animal farming sector. Meaningful collaborations are also with the Animal Task Force, EATiP, the European focal point on Animal Genetic Resources, and other international organisations, such as the FAO and ICAR. More can be done. And together, through dialogue and innovation, we can shape a more sustainable and responsible future for European animal agriculture and aquaculture.

NEWS 8 FEED & ADDITIVE MAGAZINE June 2025 Orffa announced that Excential Energy Plus, one of its leading innovations, was officially certified under the Global Feed LCA Institute (GFLI) Branded Data Methodology. The company emphasizes that this recognition positions Excential Energy Plus as the first Nutritional Emulsifier globally be independently validated for its environmental footprints. The certification confirms the product’s contribution to sustainable livestock production and supports feed manufacturers and integrators in reaching their climate goals, according to the announcement. It also offers peace of mind for technical teams and purchasing managers seeking proven, low-footprint solutions without sacrificing animal performance. “The GFLI certification of Excential Energy Plus is not just a validation; it showcases Orffa's guiding principle. We see science, transparency, and sustainability as essential competences in developing high-performing nutritional solutions that give nutritionists confidence in achieving both production targets and sustainability objectives,” says Prince Nanda, Global Solutions Director at Orffa. The GFLI database is a globally recognized reference for environmental impact data in animal nutrition. By achieving this certification, Orffa takes points out it leading role in aligning product innovation with transparency and measurable sustainability performance. Read more>> dsm-firmenich Animal Nutrition & Health announced a strategic partnership with Allix, a global feed formulation software, developed by A-Systems, to measure and manage the environmental footprint of animal feed. The two organisations have agreed to combine dsm-firmenich’s Sustell™, its lifecycle assessment (LCA) platform with Allix’s feed formulation software to reduce the environmental footprint of feed. Powered by Sustell™, Allix is developing a dedicated sustainability module that will enable users to gather insights on the environmental impact of their feeds. According to the announcement, users will be able to automatically ingest their data into Sustell™ while formulating in the Allix environment. The module will be available as an add-on to the Allix subscription. David Nickell, dsm-firmenich's Vice President of Sustainability & Business Solutions for Animal Nutrition & Health says: “Feed is a vital component in the food value chain and by combining the innovative Sustell™ platform with Allix’s established feed formulation software, we are unifying our joint commitment to developing the entire farmto-fork data ecosystem. Sustell™’s LCA footprinting platform is essential throughout the value chain to address sustainability challenges and unlocking significant value.” Read more>> Orffa secures GFLI certification for its nutritional emulsifier dsm-firmenich and A-Systems partner to reduce environmental footprint of feed Photo: Freepik.com

NEWS FEED & ADDITIVE MAGAZINE June 2025 9 ADM, one of the global leaders in innovative solutions from nature, revealed the new findings from a recent clinical study investigating the effects of Bifidobacterium animalis subsp. lactis CECT 8145 (PRIOME® Metabolic Health or PRIOME® MH) in both probiotic and heat-treated postbiotic forms in adult dogs. The study resulted with significant reduction in postprandial blood glucose (blood sugar) levels observed after eating a normal kibble meal, compared to dogs given placebo, during the weight loss phase. This suggests the potential role of the strain's postbiotic form in supporting metabolic health. Measurements were taken to evaluate several hormones, like GLP-1 and glucagon, which are important for multiple metabolic processes, with differences observed between sexes. This clinical trial contributes to an expanding body of evidence supporting the role of postbiotics in pet health research, paving the way for further innovation in functional pet nutrition. "These results mark an important step in advancing our understanding of the potential for postbiotics in metabolic health for pets, a health area that historically has been underserved by biotic ingredients," said Sophie Nixon, Ph.D., Head of R&D Clinical Research for Pet & Animal Wellbeing at ADM, who oversaw the trial. "With growing interest in functional ingredients for companion animals, our strain PRIOME® MH in its postbiotic form offers exciting capabilities as a dietary supplement to help maintain metabolic health in adult dogs." Read more>> BioMar Group announced a partnership for the manufacture and distribution of aquafeed through Iceland-based Fóðurblandan’s production facility in Reykjavik, marking a significant milestone as BioMar becomes the only global manufacturer with aquafeed production in Iceland. The collaboration combines BioMar’s global expertise in aquafeed manufacturing and nutritional knowledge with Fóðurblandan’s extensive manufacturing and distribution infrastructure and their deep-rooted presence in the Icelandic market. The partnership comes with an upgrading of the production facilities at Fóðurblandan to drive improved quality and performance, along with a distribution centre for the current range of existing BioMar product portfolio, which enables year-round reliable delivery to customers across Iceland, according to the announcement. “This partnership gives us a unique opportunity to deliver locally produced, high-quality aquafeed backed by BioMar’s extensive R&D capabilities,” said Paddy Campbell, VP of BioMar’s Salmon Division. “Fóðurblandan’s experience and strong supply chain infrastructure makes them an ideal partner to support our customers’ ambitions in Iceland”, he continues. To lead this new venture, Mike McLeish has been appointed as Business Unit Director for Iceland. McLeish brings extensive experience in the aquaculture industry, having held senior leadership and business development roles across multiple international markets. Read more>> New study highlights promising effects of ADM’s postbiotic on canine health BioMar strengthens Nordic presence with new partnership Photo: Freepik Shutterstock | 1938816793

NEWS 10 FEED & ADDITIVE MAGAZINE June 2025 The latest installment in Selko’s webinar series, held on May 7th, 2025, spotlighted the Global Feed LCA Institute’s (GFLI) new branded directory as a tool to support more transparent and sustainable animal feed formulation. The database has been enhanced to provide precise environmental data for individual ingredient brands. The branded database involved a pilot collaboration between GFLI and Selko in 2024 to evaluate Selko IntelliBond as the first branded product added to the branded ingredient database. According to the announcement, GFLI completed an extensive, independent verification of Selko IntelliBond’s life cycle assessments (LCA) as a fundamental part of their internal and external evaluation process. This effort to elevate the transparency of ingredients used in animal feed responds to the market’s growing demand for credible substantiation of sustainability claims on products derived from animal protein. Third-party verification helps boost trust at a time when greenwashing is a growing concern in the animal protein sector. Including ingredients with verified LCAs can help formulators reduce the carbon footprint of feed and differentiate their offerings, according to Claudia Meeusen, Secretariat of GFLI. Adding branded ingredients to the GFLI database also brings more precision to feed formulation, as branded ingredients must meet more precise data standards. Kevin Perryman, Global Trace Mineral Advisor at Selko, stated: “Given that more than 50 percent of animal protein carbon emissions are attributed to feed, formulators can play a tremendous role in meeting the market’s growing demand for greater transparency and improved sustainability.” Read more>> Starting in 2026, the Triott Group companies Ottevanger, PTN, Almex, IVS, and Inteqnion will operate under one name: Ottevanger. Together, they deliver complete solutions for the global animal feed industry – from designing and building individual machines to delivering fully integrated turnkey projects. This includes automation, commissioning, and technical services. Triott states that, for customers, this means one clear point of contact throughout the entire process. At the same time, the new structure provides greater clarity: One organization covering the full scope – from design to maintenance. This minimizes internal transitions, accelerates processes, and ensures consistent quality, even in the long term. The choice for the name Ottevanger is a logical one, according to the announcement. Established in 1909, the name holds a strong international reputation in the industry. By bringing all expertise together under one name, the integrated project approach will become even more visible in the market. Automation plays an increasingly important role in this. By connecting systems and using data intelligently, customers gain greater control over their production – enabling them to optimize efficiency, quality, and sustainability. This applies both to individual machines and to fully integrated factories where all process steps and control systems function as one seamlessly integrated system. Read more>> Latest Selko webinar highlights importance of GFLI’s branded directory Triott to merge its companies under Ottevanger brand Photo: Selko

NEWS FEED & ADDITIVE MAGAZINE June 2025 11 Mars, Incorporated announced the expansion of its U.S. Royal Canin® manufacturing capacity through the opening of a 450,000 square-foot facility in Lewisburg, Ohio. The $450 million site will create up to 270 new full-time jobs over the next five years united around a cat and dog-first culture and will produce enough dry pet food to feed 4 million pets annually. In the United States, Mars has a presence in 49 states, employs over 70,000 Associates and operates 37 factories in addition to veterinary clinics, labs and 14 global and regional offices. Poul Weihrauch, CEO of Mars, Incorporated, said: “Our latest investment in Ohio is an important milestone in Mars ongoing commitment to U.S.-based manufacturing. Over the last five years, we invested over $6 billion in the U.S. and we plan to continue to grow our ability to supply the domestic market. The Royal Canin facility in Lewisburg provides an important opportunity to further Mars science-based innovation while supporting a community of people and pets that has long been a part of the Mars family.” Mars notes that the state-ofthe-art facility uses standardized systems and process designs tested across Royal Canin facilities to replicate the brand’s precise nutrition. The site can manufacture the brand’s entire regional dry kibble portfolio, making it the largest dry pet food factory globally for the brand. Read more>> Royal Canin expands US presence with largest dry pet food factory

NEWS 12 FEED & ADDITIVE MAGAZINE June 2025 Researchers at the University of Florida (UF), USA, are testing a new type of cattle feed that could help dairy cows release less methane gas from burps and flatulence and use nutrients more efficiently. Because methane traps heat in the atmosphere, reducing these emissions could make dairy farming more environmentally friendly and sustainable. Researchers, led by Antonio Faciola, looked at a potential dairy cattle supplementary feed made of flaxseed and pea protein. The study was published in April, 2025, in the Journal of Dairy Science. Methane, a potent greenhouse gas, is naturally emitted by cows during digestion, and cows are significant sources of methane worldwide, especially from their burps. When cows’ stomachs make methane, they lose valuable energy that could otherwise be used to make milk or meat. By feeding them in a way that reduces methane output, researchers might be able to help the cow produce more milk while also chasing climate goals. “It’s a win-win situation. Every time we reduce methane, we keep that energy in the cow’s body,” pointed out Antonio Faciola, Associate Professor at UF’s Department of Animal Sciences. University of Alaska Research Assistant Professor and former UF post-doctoral student James Vinyard was critical to the study, he said. Vinyard simulated dairy cattle’s digestion in the lab to see how much methane was produced and to examine possibilities of improving that fermentation by adding a supplemental feed. Read more>> Kemin Industries, a global ingredient manufacturer, announced the acquisition of Bactana®, a research-driven company specializing in advancements in intestinal health and fermentation technology for animals. Bactana was launched from Cornell University's McGovern Center in 2017 and currently operates from UConn's Technology Incubation Program (TIP). The company points to this strategic investment by Kemin Nutrisurance: Pet Food and Rendering Technologies as underscoring its commitment to scientific innovation and the continuous expansion of its expertise in gut health. "Compelled by curiosity, we are reinforcing our dedication to developing novel solutions that support metabolism, immune function, and overall well-being by combining Bactana's cutting-edge research with our existing expertise," said Kimberly Nelson, President of Kemin Nutrisurance. "This acquisition aligns with our long-term vision to explore emerging technologies in intestinal health and further strengthen our position as an industry leader." As part of this integration, Kemin Nutrisurance will leverage its global resources and scientific expertise to advance research and accelerate the development of innovative solutions in this evolving field. The company regards the acquisition as representing another step forward in its mission to enhance health and nutrition through pioneering science and technology. Read more>> Florida University scientists test new supplement to cut dairy cow methane Kemin expands innovation in pet intestinal health

NEWS FEED & ADDITIVE MAGAZINE June 2025 13 IFFO – The Marine Ingredients Organization unveiled that, in March 2025, total cumulative fishmeal production reported in its market intelligence* increased by approximately 29% compared to the same period in 2024. This increase was reportedly primarily influenced by a significant uptick in Peru, while Chile, the USA, Spain and the African countries also reported a positive performance compared to January-March 2024. As for fish oil, total cumulative output for the year through March 2025 was 34% up year over year, again mainly driven by Peru. The other regions reported a positive trend in cumulative fish oil production compared to January-March 2025, with the exception of the European countries. China’s latest fishing bans were implemented on May 1st. Until the next fishing season in August and September, most of the raw materials to produce fishmeal and fish oil will come from frozen fish and raw materials imports (such as sardine raw materials). Farmgate prices for several species with high fishmeal dietary needs have exceeded year-ago levels. As a result, higher domestic production of aquaculture, and better demand for marine ingredients is anticipated throughout 2025, IFFO states. Similarly, pig farmers have expressed growing optimism for the second half of the year, prompting an acceleration in piglet purchases. Strong, unexpected demand for piglets to date is likely to drive up piglet feed production and fishmeal consumption in 2025. According to the announcement, prices of plantbased feed ingredients—such as soybean meal, corn, and rapeseed meal—have risen due to supply constraints exacerbated partially by the ongoing trade conflict. In response, feed producers are actively seeking alternatives to soybean meal or reducing its inclusion in feed formulas to better manage overall costs. Read more>> IFFO: Global fishmeal and fish oil production up in Q1 The Foundation for Food & Agriculture Research (FFAR), Dairy Management Inc. (DMI) and Zoetis launched the Dairy Health, Efficiency & Resource Dynamics (Dairy HERD) Initiative. The goal for this $1.3 million research collaboration was unveiled as to advance research in animal health, ensure the economic viability of the U.S. dairy industry and improve environmental outcomes. FFAR is currently accepting research proposals requesting between $500,000 and $1 million per project for projects lasting up to two years. The required matching funds for this opportunity have been secured, but additional matching funds are encouraged. “FFAR is excited to partner with DMI and Zoetis to fill critical animal health research gaps. This research initiative will not only help to increase profitability for farmers but also support the dairy industry in achieving their stewardship objectives,” said Jasmine Bruno, Ph.D., Scientific Program Director - Cultivating Thriving Production Systems at FFAR. Read more>> Dairy HERD Initiative aims to fill critical animal health research gaps

NEWS 14 FEED & ADDITIVE MAGAZINE June 2025 Consumers want antibiotic-free meat and farmers need reliable ways to keep their flocks healthy. Clemson University, based in South Carolina, USA, unveiled it is helping meet both goals through research that explores natural alternatives to antibiotics in poultry production. The poultry industry is big, bringing in $2.5 billion annually for the South Carolina economy. A common gut disease in chickens, called necrotic enteritis (NE), creates an economic burden due to reduced production, increased mortality and the need for expensive treatments. Antibiotics are often used to treat this disease. But Clemson University researchers say natural products like black cumin, kefir and bacteriophages may work just as well — and meet the growing demand for antibiotic-free chicken. “We’re learning how gut bacteria affects chicken health,” said Vishal Manjunatha, a Clemson researcher who recently graduated with a doctorate in food, nutrition and packaging sciences. “This can help farmers use fewer antibiotics and still keep chickens healthy.” In his study, “Exploring natural products as alternatives to antibiotics…”, Manjunatha found several natural ingredients that help fight NE in chickens: • Black cumin oil helps chickens survive NE and protects their intestines without affecting growth. • A mix of black cumin and bacteriophages stops chickens from dying from NE and improves gut health. (Bacteriophages are viruses that kill only harmful bacteria.) • Kefir, a drink made from fermented milk, boosts the immune system and helps good bacteria grow in the gut. Read more>> Alltech will welcome global thought leaders and innovators to the Central Bank Center in Lexington, Kentucky, USA, from May 18–20, 2026, for its Alltech ONE Conference, which will provide an immersive exploration of the bold ideas shaping the future of agri-food. “Over the last 40 years, Alltech has created a truly unique event, the only one of its kind, which many hail as the premier international agri-food event,” said Dr. Mark Lyons, president and CEO of Alltech, one of the global leaders in animal health and nutrition. “ONE 2026 will again congregate thought and action leaders, scientists, food producers, entrepreneurs and storytellers in a spirit of open collaboration to explore what’s next for our industry — and our planet.” In 1985, Alltech held its first iteration of the conference in Lexington, welcoming guests from around the world to engage with experts on trending topics in the agriculture industry. Since then, ONE has become a catalyst for inspiration, innovation and collaboration across the agriculture industry and beyond. The conference was held in Lexington until 2023, when Alltech took the ideas and inspiration of ONE on the road to six countries and four continents as the Alltech ONE World Tour. “After years of connecting virtually and exploring the world together through regional experiences, we’re bringing the Alltech ONE Conference home to Lexington,” added Lyons. Read more>> Clemson University unveils antibiotic-free way to raise chickens Alltech ONE Conference set to return in May 2026 Photo: Clemson University

NEWS FEED & ADDITIVE MAGAZINE June 2025 15 One of the global leaders in laboratory technologies, BUCHI Labortechnik AG acquired Si-Ware Systems' NeoSpectra platform, including its handheld Near-Infrared (NIR) analyzer and the NeoSpectra cloud-based software portal for data, device, and calibration model management. By combining Si-Ware Systems' field-ready solutions with its high-end laboratory, at-line, and on-line NIR analysis expertise, BUCHI explains it now delivers an integrated ecosystem that enhances quality assurance and enables data-driven decisions across the supply chain, particularly in industries such as food, feed, and chemicals. “With this strategic acquisition, BUCHI becomes the only provider to offer a fully integrated NIR ecosystem - including innovative handheld solutions - designed to meet the unique analytical needs at key stages of the supply chain in food, feed, and chemical industries,” stated Thomas Braunschweiler, CEO of BUCHI. Whether at the sourcing stage, during production, or for final quality checks, BUCHI aims to ensure instant, precise, and non-destructive analysis. By uniting all instruments under the interconnected open NeoSpectra software platform, stationary and portable solutions work together harmoniously, offering comprehensive functionality for diverse applications. In addition, the company points to the system as allowing seamless transfer of calibration models across devices and from different manufacturers. Read more>> Buchi acquires NeoSpectra platform for integrated NIR ecosystem BUCHI Labortechnik AG Superior Animal Feed Solutions We build equipment that just runs. CPM is the world’s leading provider of innovative and automated solutions for new equipment and aftermarket.

NEWS 16 FEED & ADDITIVE MAGAZINE June 2025 At a decisive moment for the ecological transition, Rete Clima - a technical body and one of the leading realities in Italy in the development of ESG projects for companies - entered into a technical and market partnership with Vetos Europe, a major international player in the livestock sector. The collaboration project aims to contribute to the decarbonization of the livestock sector through the use in the animal diet of the natural/natural identical feed supplement Anavrin, developed by Vetos Europe. According to the announcement, this natural product is in fact able to reduce the amount of methane produced by ruminants through enteric methanogenesis. Methane is a greenhouse gas up to 28 times more polluting than carbon dioxide, and therefore co-responsible for global warming and global warming, a reduction of it allows for a concrete and measurable reduction in the carbon footprint of raising bulls, calves, dairy and beef cows and sheep. “We are thrilled to be able to contribute to the pursuit of sustainability goals through the development of the first project for the creation of Voluntary Carbon Credits in Italy through a partnership with Rete Clima, a leading company in the sector,” commented Gianluigi Sgarbi Partner and COO of Vetos Europe. “This project represents for us the crowning of a dream born years ago aimed at making the world we live in a better place for the future of our children by investing in innovative technologies aimed at protecting our planet using nature and putting the farmer at the center of the project itself.” Read more>> The animal feed manufacturing industry demands precision and efficiency, particularly in ingredient formulations. Traditionally, formulations are manually entered into systems, making the process tedious and prone to errors. This not only hampers scalability but also leads to costly external installations. As a result, manual processes often cause delays and inconsistencies, ultimately affecting overall production efficiency. Aboitiz Foods explains that formula precision is more than just a technical requirement for the company, it reflects its commitment to delivering safe, high-quality, and performance-driven feed products. In an effort to streamline its processes and embrace digital transformation, the BITS (Business and IT Solutions), Robotics, Automation & Integration (RAI) team developed the Bestmix Weigher app, a tailored solution for Gold Coin Medan, Indonesia. This innovative app streamlined and modernized the weighing process by allowing users to upload formulation data directly to the app, saving hours of manual work. Previously, operators were required to input data manually, recipe by recipe—each one containing up to 500 lines. This tedious process took around 15 minutes to complete per formulation and was vulnerable to manual errors. Read more>> Rete Clima and Vetos Europe collaborate to decarbonize livestock sector Aboitiz Foods digitalizes feed manufacturing process with new weighing app Photo: Aboitiz Foods

NEWS FEED & ADDITIVE MAGAZINE June 2025 17 The European Feed Manufacturers' Federation (FEFAC) market experts' forecasts continued stability in the EU compound feed production market for 2025. The total industrial compound feed production in the EU27 is expected to reach 146.1 million tonnes, marking a slight decrease of - 0.34% compared to 2024. This marginal change reflects relative stability across most animal production sectors, despite increasing market uncertainty and varied national market trends. The EU compound feed sector remains resilient in the face of continuing economic, geopolitical, regulatory, environmental, and animal disease related challenges, according to the experts. In 2025, EU cattle feed production is forecast at 41.285 million tonnes, a decrease of 1.4% compared to 2024. Among the major producing countries, Germany is expected to see a modest increase (+1.2%), while the Netherlands is projected to experience a significant decline of - 5.0%, mainly due to regulatory policies. Spain, the largest cattle feed producer, expects a decrease of - 3.6%. Poland, in contrast, is forecast to increase slightly by +3.9%. Most other Member States anticipate either stable or slightly reduced production levels, reflecting the overall downward trend in the sector due to environmental policies and animal deceases such as the recent outbreaks of highly infectious foot-and-mouth disease (FMD). Read more>> EU feed production expected to reach 146.1 million tons Photo: FEFAC The International Cooperation for Convergence of Technical Requirements for the Assessment of Feed Ingredients (ICCF) Steering Committee announced that it endorsed the guidance document on ‘Feed Ingredients Risk Assessment (Phase 2) of feed ingredients’. In January 2023, an Expert Working Group composed of dedicated regulatory authority and industry experts from the founding ICCF members was created to develop a guidance document providing recommendations for the evaluation of the risk of feed ingredients for the environment, if not exempted from further evaluation based on the guidance document #06 on ‘Feed Ingredients Environmental Risk Assessment Approach’. The guidance document provides a stepwise approach for further refining the Predicted Environmental Concentration (PEC) of the constituent entities contained in the feed ingredient and for evaluating the risk on terrestrial and aquatic environmental compartment. Based on various studies covering both environmental compartments, the Predicted Non-Effect Concentration (PNEC) of the constituent entities contained in the feed ingredient is defined. The safety of the feed ingredient is then evaluated by comparing the PEC and the PNEC (i.e. the risk quotient) for each of the relevant constituent entities. If the risk quotient in less than one (1) for all the constituent entities, the feed ingredient is not expected to present a risk for the environment. Read more>> ICCF publishes guidance on feed ingredients environmental risk assessment Photo: ICCF

NEWS 18 FEED & ADDITIVE MAGAZINE June 2025 Infectious animal diseases are affecting new areas and species, undermining global food security, human health and biodiversity, according to the first State of the World’s Animal Health report, published on May 23rd, 2025. The new annual assessment, published by the World Organisation for Animal Health (WOAH), provides the first comprehensive review of animal disease trends, risks and challenges, from the uptake and availability of vaccines to the use of antibiotics in animals. Released ahead of WOAH’s 92nd General Session and its Animal Health Forum – where leading experts gathered to discuss vaccination and innovation in disease prevention from May 25–29 – the report sets the stage for high-level discussions on how science-based vaccination strategies and emerging technologies can help address current and future animal health threats through a One Health approach. Among its findings, the report revealed the reported number of avian influenza outbreaks in mammals more than doubled last year compared to 2023 with 1,022 outbreaks across 55 countries compared to 459 outbreaks in 2023. The authors highlighted that, while the risk of human infection remains low, the more mammalian species such as cattle, cats or dogs infected, the greater the possibility of the virus adapting to mammal-to-mammal, and potentially human, transmission. “The spread, prevalence and impact of infectious animal diseases is changing, bringing new challenges for agriculture and food security, human health and development, and natural ecosystems,” said Dr. Emmanuelle Soubeyran, Director General of WOAH. “By launching a new, annual assessment of the state of the world’s animal health, WOAH shines a light on our interconnected health issues and the solutions that can improve animal health and, by extension, global health.” Read more>> A developer of premium nutritional products for dairy and beef cattle, Papillon Agricultural Company launched a new anti-caking agent DeTerra 365™ to support ruminant immune function with improved feed hygiene. Designed for use in dairy and beef cow rations, the company describes DeTerra 365 as a consistently pure calcium montmorillonite clay used to bind moisture in feed, limiting the potential for mold growth and mycotoxin production. “DeTerra 365 is a top-of-the-line anti-caking agent that supports immune function,” said Papillon President David Briggs. “Plus, we are able to price it competitively because we source it straight from a proven, pure deposit in Nevada through our sister company MIN-AD.” DeTerra 365’s unique structure and small particle size provides a high surface area for cation exchange, making it an excellent feedstuff flow agent, Papillon points out. Through this unique structure and consistent quality control, DeTerra 365 helps mitigate feed challenges and support healthy immune function. Read more>> New WOAH report reveals world’s animal disease trends, risks and challenges Papillon launches anti-caking agent for ruminant diets ShutterStock | 1173277306

NEWS FEED & ADDITIVE MAGAZINE June 2025 19 One of the leading providers of innovative feed solutions in the Middle East, UTRIX announced its ambitious growth plans. The company is increasing its production capacity, hiring new talent, and launching new nutritional solutions tailored to the region’s specific challenges. Michel Daher, Business Support Director at UTRIX, explains: “We have the team, the market knowledge, and the customer connections to make a real difference. Being from the region, we understand the unique challenges our customers face, such as climate and feed quality issues. We are committed to delivering solutions that truly meet their needs and support bird performance, health, and efficiency.” To support the mission of UTRIX, the company points out it has intensified its efforts to expand its presence, opening a new regional office and warehouse in Abu Dhabi to better serve customers in the so-called GCC (Gulf Cooperation Council) countries including UAE, Oman, Qatar, Kuwait, and Bahrain. “The new hub in Abu Dhabi allows us to deliver faster service of our innovative feed solutions and expert technical services to this part of the Middle East,” Daher expresses. In addition, UTRIX also expanded in the non GCC countries and opened an office in Jordan to streamline product registration and manage direct sales in the country. Also its distributor network has been expanded. These steps made over the past 2 years have increased the total number of staff from 60 in 2020 to over 140 today, UTRIX reveals. Read more>> UTRIX to expand production capacity and regional presence in Middle East www.argentaglobal.com Challenges of animal health and nutrition regulations to innovation Healthy Animals. Let’s Make It Happen,Together. The European Federation for Pharmaceutical Sciences, the German Pharmaceutical Industry Association and Argenta are pleased to invite you to the inaugural conference 3-4 July 2025 Munich, Germany

NEWS 20 FEED & ADDITIVE MAGAZINE June 2025 Goterra announced the successful completion of its first large-scale rendering trial, marking a significant milestone in the commercialisation of insect protein in Australia. Conducted using larvae aggregated from all operational sites and processed with an external regional NSW rendering partner, Goterra explained that the trial produced insect meal containing >70% protein and ~12% fat, exceeding industry requirements, outperforming conventional benchmarks like soymeal and more in line with premium fish meals. “This trial validates a core part of our thesis,” said Olympia Yarger, CEO of Goterra. “Aggregated food waste inputs don’t compromise protein quality. It's a key step forward in demonstrating the consistency and scalability of our product.” This successful trial also marks a deliberate and strategic step in Goterra’s evolution by externalising the rendering process and focusing on core competencies in organics waste processing technology and protein production, according to the announcement. Outsourcing the rendering of BSF meal, oil, and tallow creates better pathways to scale more efficiently and deliver on the current infrastructure gap for food waste processing in Australia. The trial follows the announcement of a landmark partnership between Goterra and Skretting Australia in 2024 to integrate insect protein meal into aquaculture feed. As global demand for sustainable, traceable feedstocks increases, partnerships like this are critical to accelerating Australia’s circular economy. Read more>> Goterra marks milestone with first large-scale insect protein rendering trial Photo: Goterra Manuchar Pakistan entered into a strategic partnership with Evonik, one of the global leaders in feed additives, to distribute and market their MetAMINO®. Manuchar points to the collaboration as an important milestone in its ongoing strategy to expand its feed additives portfolio across emerging markets, where the company has a strong and growing presence. By combining Manuchar’s trusted local distribution network, deep market knowledge, and commitment to ESG standards, compliance, and service reliability, with Evonik’s high-quality branded products and global expertise in animal nutrition, this partnership is set to deliver value to the animal feed industry in Pakistan, according to the announcement. As part of the agreement, Aaqib Munawer Hussain, the Manuchar Pakistan Country Manager, expressed the significance of this collaboration: “We’re thrilled to partner with Evonik as their exclusive distributor for Methionine in Pakistan. This agreement is a key milestone for us, unlocking new opportunities for growth and innovation. It strengthens our position in the market and paves the way for long-term success, allowing us to deliver high-quality solutions to meet the growing demand in Pakistan.” Read more>> Evonik makes distribution agreement with Manuchar Pakistan Photo: Manuchar

NEWS FEED & ADDITIVE MAGAZINE June 2025 21 At the Pennsylvania State University, researchers discovered that metformin, a drug usually prescribed for type 2 diabetes and polycystic ovary syndrome (PCOS) in humans, can actually help chickens lay more eggs. Specifically, it helps broiler breeder hens — the chickens that produce the broiler chickens we eventually eat — stay fertile and produce eggs for longer, even as they age. While the team has known that metformin can help egg production in chickens for a couple of years, they recently discovered how it works. They published their findings in the Biology of Reproduction journal. Broiler breeder hens have been selectively bred for decades for their offspring to grow quickly and reach market weight fast — a trait that helps meet the world’s demand for affordable chicken meat. But there’s a trade-off: As these birds age, their ability to lay eggs declines rapidly, limiting how long they can remain productive. This drop in fertile egg production resembles PCOS in humans, which also affects fertility and ovarian function. That’s where metformin, a common treatment for PCOS, enters the picture. Read more>> Penn State study links common diabetes drug to improved egg production Credit: Hispanolistic/Getty Images A group of industry professionals are exploring a fishmeal alternative derived from marine sources to evaluate potential benefits for gut health and growth performance in meat chickens. The Innovate UK initiative, “Farmed Marine Proteins for Poultry Feed”, assessed the viability of using Artemeal – a protein product made from artemia – as a novel replacement for fishmeal in the diets of young broilers. The aim was to monitor health outcomes, optimise growth and reduce environmental impact. Aquanzo Ltd, the project’s lead partner, has collaborated with Scotland’s Rural College (SRUC) and the UK Agri-Tech Centre to introduce a sustainable alternative to traditional fishmeal, offering a long-term solution to the current marine protein ingredient crisis. Lee Cocker, Project Manager at the UK Agri-Tech Centre, expressed: “This has been an important and fascinating project and I am extremely proud to have been part of a team that has made such positive advances. The future is bright for Artemeal.” Traditionally, marine ingredients, in the form of fishmeal, are considered among the most nutrient-rich feed options for young terrestrial animals (like chicks and weanling piglets) and aquaculture species. However, the environmental toll of harvesting wild marine resources is significant, involving substantial greenhouse gas emissions from long distance transport and a delicate reliance on ecosystems already under pressure from climate change. Read more>> UK project tests out novel marine protein to enhance poultry diets

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