ISSUE FOCUS FEED & ADDITIVE MAGAZINE November 2025 63 the epithelium level (strengthens rumen post-calving), boosting DMI post-calving and milk production. When supplemented before calving, the live yeast strain helps the rumen wall better prepare for the stress encountered around calving by improving rumen wall integrity (tight junctions) and resistance to rumen wall inflammation through its effects on cytokines. In a trial performed during early lactation (IRTA, Spain, 2019), Levucell SC fed cows were shown to produce 6 liters of extra milk, partly explained by a higher DMI of 2.5 kg/head/day. This higher DMI was equivalent to a higher non-fiber carbohydrate (NFC) intake in the Levucell SC group of 1.21 kg, equivalent to an extra 20%, corresponding to a higher energy supply. In another commercial trial with Holstein transition cows, Poland (2015), the same rumen-specific live yeast combined with specific yeast product from Lallemand, reduced the number of ketotic cows by 26.4% compared to the control group (Figure 3). CONCLUSION Leaky epitheliums are the central cause of inflammation and immune activation during the transition period; with consequences on health and productivity. Nutritional strategies that support gut integrity and reduce inflammation are essential for a smooth and successful transition period. Among other animal management practices not detailed in this article, pro and postbiotic feed additives that can help maintain balanced rumen microbiota and epithelial integrity during the transition period can support cow health and high performance under such challenging conditions, yielding high economic outcomes. References 1. Boylen, K. 2022, April 6. The common denominator: leaky gut syndrome. Progressive Dairy | Ag Proud. https://www.agproud.com/articles/28372-the-common-denominator-leaky-gut-syndrome 2. Horst, E., Kvidera, S., & Baumgard, L. 2021. Invited review: The influence of immune activation on transition cow health and performance—A critical evaluation of traditional dogmas. Journal of Dairy Science, 104(8), 8380–8410. https://doi.org/10.3168/ jds.2021-20330 About Marie-Valentine Glica An agronomist Marie-Valentine Glica has been working for Lallemand Animal Nutrition for 5 years as global ruminant marketing manager. Glica is in charge of marketing and communication for the feed additives range (trial valorization, on-farm services and training tools development). She has previous experience in technico-marketing in healthcare for large and young ruminants. 37.5 11.1 % of Cows with BHBA>=1,2mmol/ 0 5 10 15 20 25 30 35 40 Control Post-biotic % of Ketotic Cows Figure 3. Effect of postbiotic supplementation containing S. cerevisiae CNCM I-1077 on the number of ketotic cows when supplemented one month before calving until two months after calving.
RkJQdWJsaXNoZXIy MTUxNjkxNQ==