ISSUE FOCUS FEED & ADDITIVE MAGAZINE November 2025 41 ity and fecal volume, prolongs passage rate, and reduces defecation frequency. Additionally, it is almost 100% fermentable for a positive effect on microbiota growth. DiaReset combines two natural probiotic strains that suppress the growth of non-beneficial bacteria while promoting the growth of lactic acid producing bacteria, participating in beneficial immune modulation, and increase nutrient digestibility through the production of digestive enzymes. Together, these powerful probiotics stabilize the gut microbiota. Prebiotic yeast cell walls from hydrolyzed yeast complete the synbiotic component of DiaReset. This prebiotic can bind gram negative pathogens such as E. coli and Salmonella and help to prevent these pathogens from adhering to the intestinal wall as well as modulating and stimulating the immune system. Hydrolyzed yeast also provides functional amino and nucleic acids to support intestinal development and beneficial intestinal microbiota. DiaReset also contains a source of saponins—compounds that are part of the defense mechanism of some plants. These saponins have been shown to have antiprotozoal, antibacterial, anti-inflammatory, and immunostimulatory properties. Their effects on protozoa are particularly important as cryptosporidia is a top cause of calf diarrhea. By complexing with a cholesterol moiety of protozoan cell membranes, saponins can induce pore formation, cell lysis, and death. DiaReset is supplemented with vitamins to support immune function and a highly bioavailable source of zinc. Zinc has many roles, including antioxidant functions, immune support, and tissue repair and healing. This includes the gut, where zinc stimulates cell proliferation, helps restore the mucosal lining, and improves barrier function. FIELD-PROVEN RESULTS A 12-week field trial was conducted to evaluate the effect of DiaReset on the regeneration and performance of calves with diarrhea. Calves (n=23) less than two weeks old that were showing signs of diarrhea were assigned Photo: Biochem
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