ISSUE FOCUS FEED & ADDITIVE MAGAZINE October 2025 35 performance. A recent study in China (Xia et al., 2025) with 540 Hy-Line Brown Hens of 45 weeks of age assessed the benefits of supplying Adimix® at a dosage of 1 kg / T of feed. It was shown that Adimix® helps to reduce pro-inflammatory signals in the liver and support the immune response in the serum (Figure 4). Performance parameters were also improved. Other powerful nutritional solutions from Adisseo to support gut health are FRA® Gut Protect and FRA® Butyrin Hybrid. FRA® Gut Protect combines the antibacterial activity of short- and medium chain fatty acids with the benefits of C12 glycerides on the immune response and with tributyrin on gut development and integrity. FRA® Butyrin Hybrid combines the benefits of glycerides of butyric acid on intestinal integrity and pathogen control in one unique concept. It stimulates intestinal health and development and improves animal performance. CONCLUSION As resilience to disease becomes increasingly vital for the profitability of animal production, strengthening animals' immune defences is more important than ever. Supported by a science driven mindset and extensive research in animal health and immunity, Adisseo provides a comprehensive portfolio of Figure 4. Butyrate modulates immune response in laying hens. Levels of cytokines and immunoglobulins in serum and liver in hens that did not receive butyrate (grey bars), or 240 g/T butyrate in the form of precision delivery coated butyate (Adimix Precision, blue bars) or butyric glycerides (FRA Butyrin Hybrid, pink bars). Photo: zlikovec | ShutterStock
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