Feed & Additive Magazine Issue 56 September 2025

ADVERTORIAL 46 FEED & ADDITIVE MAGAZINE September 2025 release mode of plant extracts to the specific physiological needs of the target animal species. This work has enabled us to design and validate, within our laboratory, three innovative release kinetic profiles based on differentiated encapsulation and process, optimized by rigorous in vitro trials: • CAPS-QR “Quick Release”: This allows for immediate release in the upper digestive tract. Ideal for fast-acting extracts (immune or antioxidant stimulation), it relies on matrices that disintegrate rapidly at neutral or acidic pH. • CAPS-SR “Slow Release”: This ensures prolonged release throughout the entire digestive transit. Suited for active ingredients with sustained effects (natural anti-inflammatories, metabolic regulators), it uses coatings that modulate diffusion based on pH or enzymes. • CAPS-DR “Delayed Release”: This targets specific areas of the lower digestive system, with delayed release allowing for local action (microbiota modulation, antimicrobial effect). It relies on coatings designed to resist the initial phases of digestion. These differentiated galenic profiles offer flexibility in the use of plant extracts, allowing the release kinetics to be adapted to the biochemical nature of the active ingredient, the desired mode of action, and the animal’s physiological context. This functional release design capability, coupled with fine control over manufacturing processes, constitutes a major technological advantage for the development of new-generation natural solutions for the different species (ruminant and monogastric). APPLICATIONS IN POULTRY AND SWINE Gallicalm is a targeted phytogenic blend of aromatic substances and plant extracts, specifically formulated to control the negative effects of nervousness in poultry production. Its efficacy has been demonstrated in trials with laying hens, where it helped limit inappropriate behaviour such as feather pecking and scratching. Beyond behavioral improvements, Gallicalm also supports zootechnical performance (Figure 1). Source: Techna, 2025 1,94 1,92 1,9 1,88 1,86 1,84 1,82 1,8 1,78 1,76 37,5 37 36,5 36 35,5 35 34,5 34 1,92 FCR ADG (%) 1,82 35 37 Control Gallicalm 1kg/t Control Gallicalm 1kg/t Source: Laying hens trial Newcastle University, 2024 Average number of pecks per day before during and after Gallicalm administration Before, during and after the distribution of Gallicalm Before During After Before During 46b 61a Severe Pecking Mortality (%) 65 60 55 50 45 40 3 2,5 2 1,5 1 0,5 0 50b 2,43 0,5 0,53 After Figure 1. The effect of Gallicalm on poultry behaviour and performance

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