ISSUE FOCUS FEED & ADDITIVE MAGAZINE July 2025 57 Studies conducted by Lucta showed a decrease in crypt depth in diets supplemented with Olive Bioactives after challenging the animals with a fasting period of x 15.5 hours, evidencing the intestinal cell protection of Olive Bioactives. (Figure 4) CONCLUSION The reduction of the inflammatory status influences structural factors that, in turn, generate improved intestinal absorption of nutrients and water. Proper absorption will improve zootechnical results but, also important, will contribute to avoid specific problems in broiler production such as wet litter, an issue closely related to welfare. Improvement of gut integrity will also lead to better zootechnical results together with other aspects of health and welfare. This fact positions Olive Bioactives as ideal additives for strategies aimed at increasing the health and quality of poultry and other livestock products. References 1. Effects of a bioactive olive pomace extract from Olea europaea on growth performance, gut function, and intestinal microbiota in broiler chickens. Herrero-Encinas, M. Blanch, J.J.Pastor and others, 2020a, Pouyltry Science 99 (1):2-10 2. Diet Supplementation with a Bioactive Pomace Extract from Olea europaea Partially Mitigates Negative Effects on Gut Health Arising from a Short-Term Fasting Period in Broiler Chickens. Herrero-Encinas, M. Blanch, J.J.Pastor and D. Menoyo, 2020b, Animalsce 10:349 Crypt Depth P<0.014 Lumen ABSORPTION Crypt Villus Villus Length PROLIFERATION Crypt Depth 200 180 160 140 120 100 CF OED1 OED2 MF µm About Dr. Jose J. Pastor Holding a PhD in Organic Chemistry, Dr. Jose J. Pastor has dedicated over 20 years to research and innovation in the life sciences. Since 2013, he has been leading the Bioactives and Molecular Biology Unit within Lucta’s Innovation Division, where he focuses on developing next-generation functional additives. His work centers on the analysis of biomarkers and the exploration of phytogenic bioactives designed to support the physiological condition of animals. CF: Control OED1: Olive Bioactives low-dose OED2: Olive Bioactives high-dose MF: Monensin at 100 ppm Herrero-Encinas et al., 2020b (Animals) Figure 4
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