ISSUE FOCUS FEED & ADDITIVE MAGAZINE July 2025 37 ileal secretary IgA levels were increased by Arg supplementation. Secretory IgA is the primary immunologic barrier preventing intraluminal pathogens from colonizing the intestinal mucosa, and this aids in maintaining homeostasis with the commensal microbiota. It may be expected that arginine plays important roles in intestinal health and immunity. The Arginine Requirement Increases in Heat Stress From market application experience, the requirement for arginine in broilers is different in different seasons. In the summer, nutritionists might appropriately increase the arginine level of the diets in order to avoid poor growth performance. A trial run Urea Cycle Ornithine Ornithine Argininosuccinate Citrulline Citrulline Arginase Arginine Carbamyl phosphate systhetase Orinthine transcarbamoylase Argininosuccinate synthetase Argininosuccinate lyase Fumaric acid AMP+PPi ATP Aspartic acid Oxaloacetic acid Amino acid Glutamic acid α-ketoglutaric acid Pi +2Pi 2ADP Carbamyl phosphate Mitochondria 2ATP+CO2+NH3+H2O Mitochondrial inner membranes Ground substance Urea H2O Figure 1. Urea cycle diagram of arginine synthesis Photo: CJ-BIO
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