Feed & Additive Magazine Issue 52 May 2025

Publisher Muhammed Akatay [email protected] Responsible Manager Özlem Akatay [email protected] Editor-in-Chief Derya Yıldız [email protected] Editors Burak Varol Zeynep Demirkaya [email protected] Communication & Marketing Lisa Atakul [email protected] Design Alper Kandemir [email protected] Web Design Caner Cem Pulat [email protected] Circulation and Data Responsible Amine Şengün [email protected] Ataturk St. Metropol Istanbul Ste. Block C1, No:376 Atasehir, Istanbul/TURKEY Phone: +90 850 220 5064 E-Mail: [email protected] Web: www.feedandadditive.com Publication Type: Periodic (Monthly) EDITOR The foundation for safe and sustainable livestock farming is quality and healthy feedstuffs. But geopolitical tensions, logistical bottlenecks and fluctuations in the raw material supply disrupt the global feed ingredient supply chain and lead to inconsistent quality. They also make access to feedstuffs both more expensive and more unpredictable. When negligence in storage and transportation is added to this, the problem is not only economic, but also poses serious health risks. The smallest negligence in the post-harvest processes of feedstuffs can lead to the formation of harmful metabolites such as mycotoxins in a short time. Inadequate storage areas, inappropriate temperature-humidity balance and uncontrolled transportation conditions can render these valuable raw materials unusable. Climate change also aggravates the situation: Sudden temperature changes and increased humidity increase the risk of toxins such as aflatoxin, DON and fumonisin. These toxins not only threaten animal health, performance and welfare, but can also reach humans through animal products such as meat, milk and eggs. Today, the threat of these toxins, which weaken the immune system and cause yield losses, has reached a level that cannot be ignored in terms of public health. Today, the threat of these toxins, which weaken the immune system and cause yield losses, has reached a level that cannot be ignored in terms of public health. This situation makes feed safety not only a production issue, but also the shared responsibility of all stakeholders. To summarize, feed safety is no longer the responsibility of feed producers alone, but of everyone from farmers to the food industry, from public authorities to the end consumer. Effective inspection, proper protection and up-todate toxin management practices will shape not only the healthy production chain of today but also of the future. In an era where food safety is closely linked to feed safety, feed protection is not a choice, but a responsibility to protect the health of animals, people and the planet. As part of this responsibility, we have covered various aspects of feed safety and toxin management in this month's issue. I hope you find it a useful and inspiring read. Hope to meet you in the next one... The Frail Chain: Feed Safety in the Wake of Growing Risks Derya YILDIZ © Three Plus Media | All rights reserved. Reproduction, in whole or in part, is prohibited without the written permission of the publisher. *DISCLAIMER: All views and ideas expressed in articles published in the magazine reflect the point of views of the author(s), not that of the Editor-in-Chief, Editors, Editorial Board or Publisher of Feed & Additive Magazine. The Editor-in-Chief, Editors, Editorial Board and Publisher assume no responsibility or liability in such cases. The publisher does not give any warranty and representation to the accuracy or completeness of the contents and data published in the magazine. All responsibility of the contents, articles and information published in the magazine belongs to the authors. The publisher and the authors cannot be held responsible for any damages resulting from the use of the whole or part of the content of the magazine. feedandadditive

Quality ingredients - the recipe for better results Raw material quality plays a critical role as the starting point for producing safe feed and safe food. That’s why it’s essential to take a solution driven approach that combines analytical services, the right product portfolio and accurate dosing equipment – to combat the negative impact of moulds, mycotoxins and enterobacteria on raw materials. THE BENEFITS RAW MATERIAL QUALITY Reduce microbial risk Maintain value Support sustainability Learn more, visit www.selko.com

CON T E N T S 24 ISSUE FOCUS FEED SAFETY & TOXIN MANAGEMENT 35 MANAGING THE HEALTH RISKS OF EMERGING MYCOTOXINS Josep Garcia-Sirera, Agrimprove 42 TACKLING FUMONISINS: A NEW ERA IN ANIMAL HEALTH Mariano Gomory, MIAVIT GmbH 44 MYCOTOXIN TESTING FOR MILLERS: ENSURING SAFE AND HIGH-QUALITY FEED Anneliese Müller, dsm-firmenich 48 MANAGING MYCOTOXIN RISKS IN ASIA-PACIFIC AQUACULTURE Dr. Vivi Koletsi, Alltech Coppens 51 8 OUTTAKES FROM THE 15TH WORLD MYCOTOXIN FORUM: MANAGING CHAOS AND COMPLEXITY Dr. Swamy Haladi, Trouw Nutrition 38 HARNESSING ORGANIC ACIDS TO COMBAT MOULDS AND PRESERVE GRAIN QUALITY Eugenio Alcalde, Selko 26 THE RELEVANCE OF MYCOTOXIN MITIGATING STRATEGIES ON DAIRY FARMS Dr. Cornelia Becker, Biochem 32 MYCOTOXINS AS CONTRIBUTORS TO ANTIBIOTIC RESISTANCE? Dr. Inge Heinzl & Marie Gallissot, EW Nutrition

CON T E N T S Evonik highlights sustainability benefits of portfolio 88 Difagri joins forces with Alinova to strengthen its position in animal nutrition 96 Agri-Food Outlook: Global feed production increased by 1.2% in 2024 14 Cargill honored with Edison Award for its layer innovation 20 CCPA Group strengthens South American presence 16 NEWS 22 BIG DATA IS TRANSFORMING DAIRY FARMING By Dairy Data Warehouse 64 FUTURE CHALLENGES FOR POULTRY: OUR VISION AT LUCTA Jesús Rubio, LUCTA 54 THE POWER OF REAL-TIME LAYING HEN BODY MEASUREMENT FOR PRECISION NUTRITION Lieske van Eck & Inês Carvalhido, Cargill ANH ADVERTORIAL 68 POWER PEAK PERFORMANCE WITH SMARTER FEED MANAGEMENT Yianna Rhodes, VAS 70 PRECISION FARMING AND BIOTECHNOLOGY Joe Hugill, Skills Alliance TECHNOLOGY 58 FEED EFFICIENCY: THE CHALLENGE OF A DAIRY COW Alizé Philouze & Jamie-Leigh Douglas, Techna Nutrition 73 EPIGENETICS AND IMMUNITY, HEALTH, AND LONGEVITY IN DAIRY COWS Dr. Alvaro Garcia, Dellait Animal Nutrition and Health ARTICLE MARKET REPORT ALGAE-BASED ANIMAL FEED AND ITS GLOBAL MARKET STATUS 76 Derya Yıldız, Feed & Additive Magazine

6 FEED & ADDITIVE MAGAZINE May 2025 Since the EU exit on 31 January 2020, the UK animal feed industry is managing the implications of departure from the trade bloc including, those for trade, regulation, and the ambition of the UK Government to improve food security. TRADE The UK industry sources 16mt of raw materials annually, with 54% from home-grown origins and the remainder globally. This exposes the industry to geopolitical shocks such as Covid, the war in Ukraine, Suez supply challenges, and now a looming global trade war. It would be fair to conclude that the UK animal feed industry has yet to see benefits from the EU exit. However, independent of the EU, the UK may navigate a competitive advantage, with US tariff proposals and EU countermeasures being a prime example. The initial US tariff proposal for EU goods was 20%, whilst only 10% for UK goods. In response, the EU proposed countermeasures of 25% on various US food and feed goods. The UK has not imposed any tariffs to date, but the Government is consulting on the issue. The UK imports various feed materials and additives from the US, either directly or via the EU. These include maize, soya beans and meal, beet pulp, beet molasses, distiller’s dried grains with solubles (DDGs), corn gluten, a range of feed additives, and amino acids. Another example of an independent UK trade policy that benefits the feed industry is the decision not to place any anti-dumping measures on Chinese lysine imports. The EU provisional measures were set out in Implementing Regulation (EU) 2025/74 on 13 January 2025 and, if imposed, will have considerable economic implications for the EU industry. However, Northern Ireland feed businesses importing Chinese lysine will be subject to EU measures, though these may be reversed under the Windsor Framework. The Agricultural Industries Confederation (AIC), representing the interests of the UK feed industry, is engaged in discussions with the UK Government on tariffs and will be seeking a positive outcome for Members. While trade policies are crucial, another significant area of focus for the UK feed industry is the regulatory landscape, particularly the opportunity to negotiate a UK/EU Sanitary and Phytosanitary (SPS) Veterinary Agreement. UK/EU SPS VETERINARY AGREEMENT AIC has engaged in separate discussions with the Department for Environment, Food and Rural Affairs (Defra) over the Government’s ambition to negotiate an EU-SPS veterinary agreement. The Government has now begun the work of negotiating such an agreement with the EU, a policy shift that could benefit the entire agri-food supply chain in the UK. Since the Government took office, AIC has been working closely with ministers and civil servants as they engage in these negotiations to help foster a beneficial outcome for Members, to remove unnecessary barriers to trade between the UK and EU. Amongst such challenges, one cannot overlook the complexities that have arisen from trade between Great Britain and Northern Ireland in SPS matters. On 19 May, a high-level EU-UK summit will take place in London, and this will form part of the discussions. CAN THE UK FEED INDUSTRY PLAY A BREXIT TRUMP CARD? James McCulloch Head of Feed Sector Agricultural Industries Confederation (AIC) LEAD ARTICLE

FEED & ADDITIVE MAGAZINE 7 May 2025 REGULATION Regulation is another area where UK policy proposals are leading to greater divergence from EU feed regulations. Simplifying the regulated products regime will benefit feed businesses. The UK Food Standards Agency (FSA) has proposed removing the need for 10-year renewals for feed additives, genetically modified organisms (GMOs), and smoke flavourings. They also suggest publishing authorisations after a ministerial decision, rather than prescribing them in legislation. These proposals are welcomed by industry and will help ensure speedier approvals for new feed additives and GMOs and remove the cost of preparing and submitting dossiers for renewals. Proposed deforestation regulations in the EU and UK have occupied much feed industry resource and, in the UK, the focus has been on identifying the differences between the EU Deforestation Regulation (EUDR) and the UK Forest Risk Commodities Regulation (UKFRC). Table at the bottom of the page highlights the main differences Again, the UK deforestation regulation proposals appear pragmatic, and the industry supports the principle of deforestation-free supply chains. AIC has engaged in discussions with food and feed supply chain partners to highlight the extra compliance costs both sets of regulations will bring. It is important to note that Northern Ireland businesses might need to follow both UKFRC and EUDR rules. A further regulatory proposal in the UK is the Precision Breeding (PB) Act, which regulates technologies such as gene-editing in plants and animals, presents an opportunity for the UK feed industry. In February 2025, UK Ministers announced that secondary legislation to implement the Precision Breeding Act for plants would be laid in Parliament. The necessary secondary legislation is expected to pass through Parliament and will allow FSA and Defra to receive applications for Precision Bred Organisms (PBOs) in England. AIC will represent the industry’s interests in the Government's Precision Breeding Working Group, to ensure consistency of PB legislation across the UK, noting that similar legislation has now taken a step further forwards in the EU. While regulatory changes are essential for industry growth, ensuring food security remains a priority for the UK Government, especially in responses to recent global challenges. UK FOOD SECURITY The UK Government has published a Food Security Report which identifies the challenges to the UK food supply chain resulting from major shocks such as: • Societal responses to the COVID-19 pandemic caused fluctuations in supply chains due to government measures and economic stimulus, • Russia's invasion of Ukraine in February 2022 disrupted energy and grain supplies, leading to higher food prices and impacting UK food security, • Conflict in the Middle East altered supply routes, showing the global trade system's adaptability, • Extreme weather conditions, exacerbated by climate change, caused further localized food chain disruptions. The report serves as an independent evidence base to inform users rather than a policy or strategy. In practice, this means that it provides the Government, Parliament, food chain stakeholders, and the wider public with the data and analysis needed to monitor UK food security and develop effective responses to issues. The UK feed industry is developing a risk register for feed materials and additives to inform discussions around food security issues – after all, food security depends to some extent on feed security. Direct Embedded Cut-off date Geolocation data Entry into force EUDR UK FRC Illegal DF1 Yes Yes Yes – first placer on the market. Importers and EU farmers Yes – annual due diligence report for businesses over £50m t/o and >500t in scope material No - ‘relevant products’ embedded in beef need to comply Yes – all in scope material embedded in all food must be accounted for Illegal con2 Yes Yes Legal DF Yes No Yes No Legal con No No Yes – Dec 2020 No 1.1.2026 TBC DF1 Deforestation — Con2 Conversion

NEWS 8 FEED & ADDITIVE MAGAZINE May 2025 Trouw Nutrition, Nutreco’s livestock feed business, announced it is collaborating with swine researchers, veterinarians, and nutritionists to share insights that decode piglets’ physiological potential during the 16th International Symposium on Digestive Physiology of Pigs (DPPNA), 20-23 May, 2025, in Lake Geneva, Wisconsin, USA. In addition to serving as a gold sponsor of DPP-NA, Trouw Nutrition will be contributing research on animal nutrition, gastro-intestinal development, water acidification, mycotoxin mitigation, and more. The company’s scientific contributions to the symposium include participation in two piglet nutrition panels and the submission of five scientific abstracts: • The balance of dietary SID Thr with total dietary fibre for weaning piglets to optimise their growth performance, intestinal morphology, and mucin secretion – Michael Wellington and co-authors, • Particle size of oat hulls in diets of nursery pigs influences their gastro-intestinal maturation – Tetske Hulshof and co-authors, • (Oral presentation) Transcriptomic insights into the ileum and hypothalamus of poorly adapted weaner pigs – Lluis Faba Camats and co-authors, • Effects of organic acid supplementation via water on the performance of weaned piglets – Karolina Von Zuben Augusto, Giseli Heim, Andrea Maria Silvestrim, and co-authors, • Effects of mycotoxin mitigation additives against the emerging mycotoxins enniatins on suckling and nursery piglet performance – Sandra van Kuijk and co-authors. Read more>> Trouw Nutrition to present piglet physiology insights at DPP-NA One of the global leaders in human and animal nutrition, ADM inaugurated a new pet food plant in Yecapixtla, Morelos. This facility, featuring three production lines and an investment of $39 million dollars, is ADM's first in Mexico dedicated to wet food for dogs and cats. Since 2008, the company has become one of the leading players in the domestic animal nutrition industry in Mexico through its brands Ganador®, Minino®, Top Choice®, and FullTrust®. ADM points out that part of this consolidation is due to significant investments, in addition to opening this new line. The company inaugurated a new production line in 2023 to expand pet food production in Guadalajara and a Macro Distribution Center in the State of Mexico. In addition to this, the care of these animals has been increasing. In fact, the Pet Nutrition Insights Report developed by the company, revealed that 79% of consumers worldwide would be willing to spend more on preventive care and premium food for their pets. In this sense, ADM explains it decided to expand its production facility in Mexico to meet the growing demand for food made with meat and other ingredients selected by animal nutrition experts, providing beloved pets with a balanced and varied diet. The Morelos Plant stands out as one of the most modern facilities of the company in Mexico. Its automated processes contribute to promoting ergonomic work for employees, reducing energy consumption and efficiently using water, according to the announcement. Read more>> ADM inaugurates first wet pet food plant in Mexico

NEWS FEED & ADDITIVE MAGAZINE May 2025 9 International technology group Andritz received an order from Alwadi Poultry Farms Company, based in Riyadh, Saudi Arabia, to deliver a complete, high-capacity feed mill for the production of poultry and ruminant feed. Andritz defines the order as a significant step in its expansion in the feed industry in the Middle East and Africa (MEA) region. The new feed plant, which will be located in Riyadh Province, is scheduled to begin operations in the first half of 2026. Designed for a total capacity of 90 tons per hour (TPH), the facility will include two production lines for poultry feed (60 TPH) and one for ruminant feed (30 TPH). Andritz will supply the complete process lines – from raw material intake to finished product – including key machinery such as hammer mills, mixers, pellet mills, and crumblers, with major components coming from manufacturing facilities in Europe. The order also includes installation supervision, commissioning, and local after-sales support by Andritz. With Andritz’s advanced technology, the plant is expected to offer high efficiency and flexibility as well as robust process control – all tailored to provide high-performance animal feed solutions for the Saudi market. Established in 1975, Alwadi Poultry Farms Company is one of the leading poultry producers in Saudi Arabia, with integrated operations spanning chicken breeding, hatcheries, feed production, and poultry processing. The investment in this new plant underlines the company’s strategy to enhance its production capacity, feed quality, and market position, according to the announcement. Read more>> Veramaris and Manolin shared the findings of a new study quantifying the commercial benefits of higher EPA and DHA in salmon feed. Big data analysis of Norway’s commercial salmon production reveals the full benefits of higher levels of dietary Omega-3 EPA & DHA on survival, feed performance and quality, giving further evidence of the return on investment in better nutrition. This new analysis uses real-world data to compare health and harvest metrics. EPA & DHA levels in Atlantic salmon diets act as levers, tipping the odds in favor of fish health and feed efficiency. The study shows how investment in nutrition helps to protect value throughout the supply chain, from farm to table. The companies report the next info about the study: “This study, which processed a decade of data from 166 farms, 430 million fish and nine Norway production zones, builds on the findings of our previously published scientific research. Mortality rates were 8% lower and eFCR decreased by 13%, while flesh quality also improved in populations fed diets rich in EPA & DHA. Improvements in predictability also increased by up to 50%, which translates into greater control over outcomes and more reliable business. “ Read more>> Andritz to deliver complete feed mill to Saudi poultry producer New study points to return on investment in salmon feed

NEWS 10 FEED & ADDITIVE MAGAZINE May 2025 Mycotoxins are toxins produced by fungi, and circa 80% of animal feeds contain two or more mycotoxins. The book “Mycotoxins: From Field to Feed”, edited by Dr. Regiane R. Santos, Senior Researcher at Schothorst Feed Research (SFR), discusses the potential risks of these contaminants for pigs, cattle, poultry, horses, fish, insects, and pets. It also focuses on prevention and detection in animal feed and on how to minimise adverse effects caused by feed contamination. The book includes contributions from international experts from all over the world and is divided into 19 chapters. For instance, Professor Tegzes from Western University of Health Sciences (USA) wrote a chapter on the effects of mycotoxins in pets, while Professor Antonissen from Ghent University (Belgium) contributed with updates related to poultry. Professor Gallo from the Catholic University of the Sacred Heart (Italy) discusses the effects of mycotoxins on ruminants, and Dr. Alassane-Kpembi from Montreal University (Canada) discusses the interaction of mycotoxins with other mycotoxins, contaminants, and veterinary drugs. Climate change plays a significant role in the increase of crop contamination with mycotoxins. As global temperatures rise and weather patterns become more erratic, the conditions that promote fungal growth are more present. This change can lead to shifts in the fungal species present in crop fields, creating an environment where more mycotoxin-producing fungi thrive. To discuss this, a chapter was written by Professor Medina from Cranfield University (UK). The main goal of Dr. Santos is to promote the interaction among farmers, nutritionists, veterinarians, policymakers, university researchers, and the feed industry. "A bridge is needed between fundamental and applied research," she says. Read more>> Global experts unite to shed light on mycotoxins in new book Leading up to World Veterinary Day (April 26, 2025), Boehringer Ingelheim unveiled new survey results that shed light on animal owners’ perceptions of the essential role that veterinarians play in animal health and community well-being. The 2025 survey of animal owners adds to a 2024 survey, also conducted in partnership with market research institute Kynetec, which explored if veterinarians feel valued and understood by animal owners. This is part of Boehringer Ingelheim’s Going Beyond campaign, which seeks to put a spotlight on aspects of veterinary work that too often remain unseen and underrecognized. “In collaboration with our Going Beyond campaign partners, we are proud to celebrate veterinary teams, bringing attention to their crucial role worldwide as animal health practitioners, advocates, researchers, educators, surgeons, public health experts and more,” said Claire Fowler, Head of Global Strategic Marketing at Boehringer Ingelheim Animal Health. The 2025 Going Beyond survey of animal owners revealed several findings, which contrast significantly with perceptions shared in the 2024 survey of veterinarians. In the 2025 survey, 94% of animal owners said they appreciate the veterinary profession, and 91% recognized that veterinary teams are essential or important to our society. By comparison, 49% of veterinarians last year said animal owners appreciate the veterinary profession. Read more>> New survey: 51% of vets feel unappreciated in their profession

NEWS FEED & ADDITIVE MAGAZINE May 2025 11 Toxin-inactivation GIT booster Immune modulator Water soluble powder MiaBond Drink Solubility gives toxin-inactivation a flexibility www.miavit.com MIAVIT GmbH Robert-Bosch-Straße 3 · 49632 Essen (Oldb.) · Germany Tel. +49 5434 820 · [email protected] MiaBond Drink gives your toxin-inactivation management a new flexibility. A combination of toxin inactivation, inflammation reduction, gastro intestinal tract (GIT) and immune system enhancer will give the best approach to boost the animal performance in early ages and stress conditions. The art of mixture.

NEWS 12 FEED & ADDITIVE MAGAZINE May 2025 In recent months, the bird flu pandemic has continued to devastate poultry operations around the world amidst continual outbreaks, tens of millions of birds lost, and skyrocketing egg prices. Avian Enterprises, LLC, an international company that provides bird repellant products for the agricultural industry and others, developed a new product – Avian Migrate® Goose and Bird Repellant – poised to offer poultry farmers a novel new solution. The U.S. Department of Agriculture (USDA) and Centers for Disease Control and Prevention (CDC) have determined that aquatic birds such as– ducks, geese and swans congregating around ponds and other bodies of water near egg producing facilities– carry and spread the virus through their saliva and feces to chicken feed and other grounds where the domestic birds reside. Avian Migrate contains ingredients approved by the EPA, including those found in food products. It is sprayed in a light mist around a facility and grassy areas within 300 feet for protection. Moreover, an InvisiDye® marker, seen only by the targeted birds, adds a visual warning in the 200-400mm spectrum with sensory and visual deterrents. According to the announcement, Avian Migrate® is a new variation on this proven technology, including how it is applied around a target area. Recently, their Avian Control® product was examined for efficacy and confirmed overwhelmingly effective in a non-peer reviewed study of dairy barn facilities by Ohio State University. A 2025 peer-reviewed study is currently being planned, Avian Enterprises points out. Read more>> USA-based company unveils new approach to bird flu Up to one fifth of the world’s greenhouse gas emissions derive from meat production, the majority of which is from pig and poultry meat. With around 60% of emissions from pig and poultry meat linked to the production of animal feed, there has been much debate within the sector over the use of alternative animal feed sources with insect-based feed gaining interest as it may require less water, energy and land resource than plant-based products. In July 2023, the UK government’s Department for Environment, Food and Rural Affairs (DEFRA) commissioned Ricardo’s sustainability team to provide an independent, scientifically robust Life Cycle Assessment (LCA) report exploring how, from an emissions reduction point of view, the production of insect protein might perform as pig and poultry feed compared to conventional soybean and fish stocks. The research looked at the potential cradle-to-gate – ie. from raw material acquisition to manufacturing and distribution - impacts of using the larvae from Black Soldier Fly Larvae (BSFL) (Hermetia illucens) reared from both permitted sources (e.g wheat-based feed) and currently unpermitted sources (e.g food waste, chicken manure). The associated potential impacts of the BSFL feed were assessed in terms of 16 environmental impact categories, including climate change, acidification, ecotoxicity, land, and water use. Comparative assessments were made for soybean meal grown in Brazil and transported to the UK, and fish meal made from blue whiting caught off the Scottish coast. Read more>> New Report: Insect protein could be 13.5 times worse for climate than soy

NEWS FEED & ADDITIVE MAGAZINE May 2025 13 Alltech announced the publication of a new white paper titled “Dietary biotics: Strategies to optimize pet intestinal health and wellbeing” by Dr. Richard Murphy, Director of Research at Alltech, and Dr. Karina Horgan, Research Group Director of Alltech’s biology division. The new white paper explores the role of pre-, pro- and postbiotics in supporting pet gut health and wellness. The paper highlights the growing importance of gut health in companion animal nutrition, emphasizing the link between a balanced microbiome and overall wellbeing. "The microbiome plays a crucial role in nutrient absorption, immune function and disease resistance," says Dr. Murphy. "By incorporating targeted dietary biotics into pet nutrition, we can positively influence gut health, mitigate the effects of harmful pathogens and improve overall pet wellbeing." A well-balanced intestinal microbiome is essential for digestion, immune response, and maintaining a healthy gut barrier. When gastrointestinal (GI) health is compromised, nutrient digestion and absorption are affected and susceptibility to disease is heightened. The paper details how specific biotic interventions — prebiotics, probiotics and postbiotics — can support a healthy gut ecosystem, ensuring improved digestive health, stronger immunity and enhanced resilience against pathogens. Read more>> New white paper highlights role of dietary biotics in pet gut health

NEWS 14 FEED & ADDITIVE MAGAZINE May 2025 Alltech, one of the global leaders in animal nutrition and biotechnology, released its 2025 Agri-Food Outlook, a report that includes the results of the company’s 14th annual global feed production survey. The publication shows that global feed production rebounded in 2024 after a stagnant 2023, increasing from 1.380 billion metric tons (mt) (+1.2%) to 1.396 billion mt. According to analysts, this growth — which was achieved despite challenges that included highly pathogenic avian influenza (HPAI), climate fluctuations and economic uncertainty — underscores the resilience and adaptability of the international agriculture industry. The annual survey that serves as the foundation of the Agri-Food Outlook collected data from 142 countries and 28,235 feed mills in 2024. By analysing compound feed production and prices — collected by Alltech’s global sales team and in partnership with feed associations and official data-collecting organizations — the survey provides a comprehensive snapshot of global feed production. These insights serve as a barometer for the overall livestock industry, highlighting key trends across species, regional challenges and opportunities for growth. The top 10 feed-producing countries in 2024 were China (which produced 315.030 million mt of feed, down 2.03% from 2023), the U.S. (269.620 million mt; +0.68%), Brazil (86.636 million mt; +2.43%), India (55.243 million mt; +4.56%), Mexico (41.401 million mt; +1.38%), Russia (38.481 million mt; +8.53%), Spain (35.972 million mt; +1.46%), Vietnam (25.850 million mt; +3.41%), Türkiye (24.502 million mt; +4.83%) and Japan (24.297 million mt; +0.14%). Together, the top 10 countries produced 65.6% of the world’s feed — and 52% of all global feed production was concentrated in just four countries: China, the U.S., Brazil and India. Read more>> Agri-Food Outlook: Global feed production increased by 1.2% in 2024 Phileo by Lesaffre, a global player in animal nutrition and health solutions, announced the launch of Safchondro® – an innovative, animal-free chondroitin sulfate product designed to support joint health and mobility in pets. Safchondro® is produced through precision fermentation using a proprietary, non-GMO microbial strain, followed by a targeted sulfation process to enhance bioavailability and efficacy, according to the announcement. The company points to this advanced manufacturing approach as offering several key benefits compared to traditional, animal-derived chondroitin sources: • Consistent Quality: Safchondro® provides a standardized, highly purified (99%) chondroitin sulfate, ensuring reliable efficacy, • Enhanced Safety: As an animal-free solution, Safchondro® eliminates potential safety concerns associated with animal-derived products and decreases the risk of allergic reactions, • Improved Sustainability: Phileo’s precision fermentation technology reduces the environmental impact compared to conventional chondroitin extraction methods, • Superior Bioavailability: Safchondro®’s low molecular weight and targeted sulfation process result in enhanced gut absorption and biological activity. Read more>> Phileo: Chondroitin solution supports joint health in pets

NEWS FEED & ADDITIVE MAGAZINE May 2025 15 European Feed Manufacturers’ Federation (FEFAC) President Pedro Cordero expressed his deep regret about the US imposition of reciprocal tariffs of 20% on the EU, covering all agri-food exports to the US. He also shared concerns about the announced EC counter tariffs including essential, critical and strategic US agri-food products and feed ingredients, like soyabeans, coccidiostats, lysine and probiotics as well as maize and co-products like corn gluten feed and DDGS, noting that current EU import tariffs are at “0 duty” level for essential US feed ingredients. Cordero urged the US and EU trade authorities “to open direct negotiations, seeking to exempt all agri-food products including essential feed ingredients from both US reciprocal and EU counter tariff schedules to safeguard global food security and resilience of the agri-food value chain.” Pedro Cordero stressed that “access to essential, critical and strategic U.S. feed ingredients is a crucial component of our collective EU and US feed chain efforts to ensure both feed and food security in the US, EU and at global level.” He referred to existing great opportunities to double US/EU Ag products and feed trade, which could contribute to close the current US Agri- food trade deficit with the EU. Read more>> FEFAC calls for direct negotiations on agri-food and feed products www.argentaglobal.com How to successfully register a mycotoxin binder: a step-by-step guide Healthy Animals. Let’s Make It Happen,Together.

NEWS 16 FEED & ADDITIVE MAGAZINE May 2025 The CCPA Group, a specialist in animal nutrition for almost 60 years, announced the acquisition of Nutrisur, a Uruguayan premix company with over 20 years of experience in the animal nutrition sector. CCPA points out this strategic operation as allowing the company to expand its presence in Latin America and strengthen its commitment to its customers in these key markets. The acquisition will be carried out through EURO-NUTEC PREMIX, a joint venture created in 1996 between CCPA Group (France) and NUTEC® Group (Mexico). Nutrisur, located in Canelones, in southern Uruguay, is a major national player recognized for its professionalism, innovation capacity, and the quality of its products and services that meet the specific needs of farmers and their animals. Nutrisur will now be able to rely on the research and experimentation resources of the CCPA and NUTEC® Groups. "This acquisition represents a key step in our growth strategy in Latin America," says Mickaël Marcerou, Chairman of Euro-Nutec’s Board of Directors. "We are convinced that Nutrisur's expertise combined with our know-how will allow us to accelerate our development and offer increasingly innovative products and services that improve the profitability, sustainability, and efficiency of farmers in Uruguay and the Southern Cone." "This investment strengthens our commitment to innovation and the development of the livestock sector. We remain determined to optimize animal nutrition through digital transformation globally," adds Jérémie Larcher, CEO of NUTEC® Group. Read more>> CCPA Group strengthens South American presence A new study led by the Food and Agriculture Organization of the United Nations (FAO) and research partners highlights that improving livestock productivity is key to achieving substantial reductions in global antibiotic use. Without targeted interventions, antibiotic use in livestock is projected to rise nearly 30% by 2040. However, the new research, published in Nature Communications, finds that strategic productivity gains in livestock systems could cut projected antibiotic use by half. The study projects that, under a business-as-usual scenario, global livestock antibiotic use could rise to 143,481 tons by 2040, an overall increase of 30% from 2019. However, alternative scenarios indicate that antibiotic use could be reduced by up to 57% if livestock productivity is optimized. By improving animal health, management practices, and production efficiency, antibiotic use could be lowered to approximately 62,000 tons by 2040, demonstrating the potential of targeted interventions in achieving global reduction goals. "Enhancing livestock production efficiency is key to curbing antibiotic use," said Alejandro Acosta, Livestock Economist at FAO and lead author of the study. "By producing more animal-sourced food with the same or fewer animals, we can reduce the need for antibiotics on farmed animals while strengthening global food security." Read more>> New FAO-led study points to productivity as key for antibiotic reduction

NEWS FEED & ADDITIVE MAGAZINE May 2025 17 Eurolysine, the sole lysine producer located in the European Union, announced the launch of a feasibility study aimed at increasing its lysine production capacity. The company points to the initiative as a reflection of its commitment to strengthening the EU’s sovereignty in essential amino acids for animal nutrition while responding to the growing demand for sustainable and locally produced feed ingredients. “Avril took over Eurolysine less than a year ago and we announced an investment plan of 130 million euros over the next five years to develop production. This investment plan has already begun and lysine production already increased significantly over the recent months. The plant will reach full speed production in Q3 2025. The study which is now launched opens a new chapter looking beyond the restauration of Eurolysine’s historical production capacity. The relaunch of Eurolysine illustrates the Avril’s determination to promote European agricultural and industrial sovereignty,” said JeanPhilippe Puig, CEO of Avril. “With this new project, we are talking about a 20% increase in production capacity at the 2027 horizon. As the only lysine producer in the EU, Eurolysine plays a strategic role in supporting the European feed industry. This feasibility study will allow us to explore innovative solutions to scale up our production capacity while maintaining our high standards of quality, efficiency, and sustainability,” added Eddy Feijen, CEO of Eurolysine. Read more>> Eurolysine unveils new initiative to expand production capacity Gut health is more than a gut instinct. Improving bird productivity through clean feed. Get the study today. www.anitox.com/broiler-performance

NEWS 18 FEED & ADDITIVE MAGAZINE May 2025 Avril took a new step in its innovation strategy with the opening of Innolab, its first integrated laboratory, located at the heart of the group’s campus in Bruz (near Rennes, France). Designed to foster cross-functionality collaboration and synergy between food, feed, and data expertise, the company describes the space as being dedicated to designing the food of tomorrow. The laboratory is focused on addressing the needs of Avril’s business units and the support of its clients. Nearly 50 researchers are united around a common mission: To provide concrete and innovative solutions and technical support to tackle the challenges of agricultural, food, and environmental transitions. Strategically located in the heart of France’s livestock region and close to the nutrition and animal expertise teams of Sanders and MiXscience, the FEED division of Innolab is designing solutions to meet key challenges in animal agriculture: Farm competitiveness and product quality, greenhouse gas reduction, disease prevention, and animal welfare. Innolab houses in vitro testing capabilities that replace traditional animal testing. By simulating the digestive systems of ruminants, poultry, and pigs, Avril notes that the lab is fully equipped to develop new nutritional and functional innovations. Read more>> Skretting China celebrated the grand opening of its new LifeStart production line in Zhuhai – Skretting’s first dedicated LifeStart facility in Asia, on April 17, 2025. At the same time, they launched five new innovative hatchery feed products, for diverse species including salmon, tilapia, golden pompano, snakehead and catfish. According to the announcement, the double celebration is significant as it signals Skretting’s confidence in the future of China’s aquaculture industry, and its commitment to supporting its long-term growth. As China is the largest animal protein market in the world, where seafood is second only to pork, Skretting and its parent company Nutreco have chosen to boost production capabilities to serve the LifeStart segment, and become the most value-driven nutrition company in China. “China is one of the most dynamic and competitive markets globally, not just in scale, but in speed of development, diversity of species, and evolving customer needs. Within the global Nutreco organisation, China plays an increasingly strategic role as a key market,” said Bastiaan van Tilburg, CEO of Skretting. “Our ambition in LifeStart in China is high. We aim to be the undisputed leader in this space by 2030, particularly for salmonids, shrimp and marine fish,” he adds. Skretting points out LifeStart products as feed products fed to larvae and juveniles in the first few months of their life, in order to influence the quality and success rate of farming through the whole production cycle. Read more>> Avril opens first internal laboratory for feed and food Skretting inaugurates its first dedicated LifeStart facility in Asia

NEWS FEED & ADDITIVE MAGAZINE May 2025 19 Based On Science Active D contains natural vitamin D glycosides and functional triterpenes, enabling a stable development and support of the animals’ in periods of stress. This is proven by numerous studies. Scan the QR code and read more about or contact our experts: [email protected] | www.phytobiotics.com Santa Livia Research Farm, Brazil 2022 Active D supports the birds in phases of high calcium demand, as it provides most available vitamin D. International Flavors & Fragrances Inc. (IFF), a global powerhouse in bioscience and innovation, announced a groundbreaking expansion of its pet portfolio. The company points to the launch as marking a significant leap in its mission to revolutionize companion animal care through advanced biotechnology and innovation. “We're excited to bring our world-class bioscience into the pet wellness space," said Dr. Jordon Gruber, Companion Animal Technical Leader, Health & Biosciences, IFF. “Our new portfolio empowers brands to tackle key challenges, delivering standout products that enhance pet health and wellness in a competitive marketplace. From improving gut health and dental care to hydration and reducing odors, we are setting a new benchmark.” Leveraging decades of expertise in human and animal wellness, IFF integrates flavors, functional technologies, processing aids, and ingredients into a cohesive ecosystem designed to drive industry innovation. IFF’s Pet Solutions are supported by specialized R&D centers, including the Pet Translational Research Lab (Wilmington, Delaware, USA), Pet Enzymes Lab (Brabrand, Denmark), and Pet Applications Lab (New Century, Kansas, USA). IFF explains these centers advance clinical science and application research, ensuring every ingredient and solution is backed by real data and impactful results. Read more>> IFF expands pet care portfolio with latest science-backed innovations

ADVERTORIAL 20 FEED & ADDITIVE MAGAZINE May 2025 SPECIAL NEWS Cargill Animal Nutrition and Health (ANH) announced that REVEAL™ Layers, its groundbreaking, non-invasive technology for monitoring hen body condition, won a bronze award at the prestigious 2025 Edison Awards™ in the category of Smart Farming & Sustainability. The Edison Awards™, held from April 2-3 in Florida, USA, honor excellence in innovation, recognizing groundbreaking technologies that drive progress in industries worldwide. Cargill points to the accomplishment as a testament to its commitment to innovation and excellence in poultry production. Through its best-in-class scientists and technical team members, Cargill ANH aims to solve customer challenges, improve their production outcomes globally, and innovate on what matters most to them. HOW CAN REVEAL™ LAYERS SUPPORT PRODUCTION OUTCOMES? Cargill explains REVEAL™ Layers as a first-of-itskind, non-invasive near-infrared (NIR) technology that monitors poultry body condition. This innovation supports poultry producers by helping to: • Make real-time decisions: REVEAL™ Layers provides real-time data on body condition, enabling precise adjustments to diet condition based on flock insights. This can help improve performance and increase profitability. • Support long-term egg production: Optimal body condition supports sustained egg production over the long term, ensuring that hens remain productive while maintaining immunity. • Improve profitability: By combining REVEAL™ Layers with Cargill’s nutritional expertise, producers can significantly reduce feed costs while maintaining high productivity. • Proven ROI: REVEAL™ Layers enables producers to achieve significant increases in eggs per hen, extend the laying period by up to 10 weeks, and realize a 15:1 ROI through precise dietary adjustments and non-invasive monitoring. WHY IS BODY CONDITION IMPORTANT? Maintaining optimal body condition is the foundation of long-term flock performance. Proper body condition supports: • Overall Hen Welfare: Supporting resilient birds. • Liver Health: Helping maintain normal metabolism. • Efficient Nutrient Metabolism: Supporting hens to convert feed into eggs effectively. KNOW YOUR FLOCK The company emphasizes REVEAL™ Layers as offering a simple, cost-effective solution to monitor fattening status, helping improve egg laying performance, and supporting animal welfare. More information about REVEAL™ Layers and how it can benefit poultry operations can be found on Cargill’s website. Cargill honored with Edison Award for its layer innovation During the Edison Awards™, Cargill’s REVEAL™ Layers won a bronze award in the Smart Farming & Sustainability category. Cargill points out that REVEAL™ Layers is a cost-effective solution to monitor poultry body condition.

NEWS FEED & ADDITIVE MAGAZINE May 2025 21 The Feed & Food Report 2024, recently published by the European Feed Manufacturers’ Federation (FEFAC), offers a comprehensive overview of the economic trends shaping the European feed sector, highlighting the industry's vital role within the EU feed and food supply chain and its contribution to the livestock and aquaculture economies. Current report presents key data from the 2023 calendar year, covering areas such as compound feed production, feed material usage, industry turnover, as well as meat production and consumption statistics. The industrial compound feed industry is a dynamic sector with slow but steady growth over the past two decades. According to FEFAC, this growth reflects market preferences of livestock and aquaculture farmers on efficient compound feed to meet increasingly stringent performance and quality standards. While the decline recorded in 2020 can be primarily attributed to the UK's withdrawal from EU production totals, subsequent decreases in production reflect broader global disruptions. Stating that factors such as the COVID-19 pandemic, geopolitical tensions, notably the conflict in Ukraine, and member states’ environmental policies, have reverberated throughout the EU livestock sector, the federation adds that these challenges have cast a shadow over the EU feed industry, contributing to a recent decline in production. Read more>> FEFAC publishes its Feed & Food Report 2024 One of the largest poultry producers in the US, Wayne-Sanderson Farms announced its partnership with BinSentry to enhance management of the company’s animal feed supply chain throughout its operations. The companies reached an agreement that will see Wayne-Sanderson Farms deploy BinSentry’s ProSense Feed sensors on feed bins positioned adjacent to poultry houses across all of its operations. According to the announcement, these sensors will provide highly accurate feed inventory tracking, allowing operations managers to identify and address potential issues in their supply chains much more quickly compared to manual processes still used in much of the industry today. With more than 2,000 farm partners and 26,000 employees at 23 processing facilities across the southeastern United States, Wayne-Sanderson points to this effort as reflecting its commitment to supporting family farmers and promoting animal welfare, sustainability, and workplace safety, while providing high-quality food to consumers. “Over the past two years, we have been working diligently to apply new technology solutions to improve the management of our animal feed supply chain, which represents our largest operating expense,” said Kevin McDaniel, CEO of Wayne-Sanderson Farms. “The BinSentry platform is a true win-win solution that aligns with our goals by improving supply chain management, replacing manual processes, and allowing us to focus on feeding our chickens high-quality feed to care for them and produce the best food for our customers.” Read more>> Wayne-Sanderson Farms and BinSentry partner for supply chain management

ADVERTORIAL 22 FEED & ADDITIVE MAGAZINE May 2025 SEAMLESS DAIRY DATA SOLUTIONS FOR BETTER DECISIONS Like many aspects of the agriculture industry, big data in dairy farming is changing the game, with businesses across feeding, genetics, sensors, and dairy advisory services leveraging standardized dairy data to improve efficiency, productivity, and sustainability. Dairy Data Warehouse (DDW) provides tools that help companies create innovative solutions, enhance herd performance, and support consultants make better decisions. DDW contributes both individual and herd-level information to assist agribusinesses with decision making across 47 countries. DDW offers seamless dairy data solutions, allowing customers to plug into herd management software, milk processing systems, MROs and TMR softwares. Customers can choose from over 120 KPIs to measure and monitor such as average lactation, average days in milk, days to conception, insemination/pregnancy rates and many more. DRILL DOWN TO INDIVIDUAL COWS DDW has detailed dairy data solutions for every individual cow on the farms we partner with—what we refer to as Individual Cow Data Marts (ICDMS). This solution offers pinpointed data on everything from a cow’s fertility to milk production. Big data in dairy farming accessed through ICDMS can show health and reproductive tracking for that animal, her milk production trends and feeding and movement data. ICDMS is ideal to help businesses build precision dairy farming tools, animal health applications, genetics solutions, or any solution requiring animal-by-animal consideration when making decisions. If your company is creating tech for the farm or veterinarians, ICDMS from DDW can be critical for your success. EXAMPLES OF DAIRY DATA SOLUTIONS IN ACTION ABC Feed Company integrates dairy data solutions from DDW to track how different rations impact milk yield across multiple dairy farms. By adjusting nutrient composition based on real-time feed conversion efficiency data, the company has helped their customers reduce feed waste while improving milk production. XY Genetics Company utilizes reproduction and milk production data from DDW to rank bulls based on real-world performance. Dairy farmers are then able to better select sires that maximize herd fertility and milk yield. Tech Sensor Company 123 integrates health and milk production KPIs from DDW with their movement tracking sensors. By combining activity data with milk yield and health records, dairy farmers can more quickly detect lameness and mastitis, lowering treatment costs. TAKE A 30,000-FOOT VIEW DDW takes individual cow data a step further, by combining dairy data solutions into herd-wide intelligence. Our herd-level insights solution, KPI Library, provides dairy data solutions that can be used for benchmarking, analytics and decision-making tools. E.g., DDW’s KPI Library can aggregate big data in dairy farming showing milk yield per herd, fertility and breeding performance for each dairy operation, and indicators for animal health and sustainability across each herd. Another example might be examining feed conversion efficiency across herds, milk yield per cow, and fat-toprotein ratio. By digging into these dairy data solutions, dairy nutritionists can ensure cows receive the right balance of nutrients to optimize milk production without overfeeding, which can be wasteful and expensive. This big data in dairy farming can be utilized to make better decisions that need to be taken at an industry-wide level. For more information, visit Dairy Data Warehouse online or on our YouTube channel. BIG DATA IS TRANSFORMING DAIRY FARMING Dairy Data Warehouse Has Been Leading the Way for Over 11 Years

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