ADVERTORIAL 82 FEED & ADDITIVE MAGAZINE April 2025 “Our research and testing prove the effectiveness of our products in reducing the risks associated with various mycotoxins. By offering science-based solutions and collaborating closely with our customers, we strive to safeguard the health and performance of their animals, and to remain a reliable and professional partner in animal nutrition and health.” Ergot alkaloids and emerging mycotoxins, such as enniatins, beauvericin, patulin, and tenuazonic acid are increasingly concerning in animal nutrition. They affect raw materials used in animal feed and can have adverse effects on animal health and performance, especially when combined with other mycotoxins. Consequences include cytotoxicity, genotoxicity, oxidative stress, reduced feed intake and nutrient absorption, impaired immune function, and other health issues. While their toxicity alone is low to moderate, their combined effects can significantly increase harm. At Cargill Animal Nutrition and Health (ANH), we recently conducted research into emerging mycotoxin risks to not only understand them, but to find science-based, proven solutions for our customers. Here is a brief overview of our latest findings. ERGOT ALKALOIDS Ergot alkaloids, produced by Claviceps fungi, are among the most studied mycotoxins. They can severely impact animal health, causing reduced feed intake, lack of milk production, abortion, and gangrene. We conducted a literature review and developed equations to quantify their effects on animal performance. This helped us establish realistic, science-based risk thresholds for different species and ages. We also studied the physicochemical properties of ergot alkaloids, enabling us to define and apply the right technologies to bind and mitigate their negative effects. In vitro tests confirmed the effectiveness of our MHS Notox™ range of products, such as Notox™ LS, which is proven to bind over 90% of various ergot alkaloids at a moderate inclusion rate of 1 kg/mT (Figure 1). OTHER EMERGING MYCOTOXINS We also examined other emerging mycotoxins, including sterigmatocystin, citrinin, fusarenon X, neosolaniol, patulin, tenuazonic acid, beauvericin, and enniatins. In-vitro tests showed Notox™ products' binding efficiencies ranging from about 60% to 100%, with an impressive average efficiency of over 80% (Figure 2). These tests further demonstrate Notox™ LS' binding efficacy with a wide array of emerging mycotoxins. These findings show that Notox™ solutions can effectively support animals MYCOTOXINS UNMASKED: NEW INSIGHTS FOR ANIMAL PRODUCERS Clement Soulet Anti Mycotoxin Agent Category Lead Cargill Animal Nutrition
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