Feed & Additive Magazine Issue 50 March 2025

March 2025 Year: 5 Issue: 50 Feed Additive INTERNATIONAL MAGAZINE FOR ANIMAL FEED & ADDITIVES INDUSTRY Aurélie Montagnon, Orffa Feed efficiency, a complex multifactorial concept in nutrition Rafaela Kava, Ocean Harvest Seaweed: A sustainable solution for feed efficiency Jose Ramirez, Anitox Beyond Waste: How rendering drives sustainability in animal agriculture www.feedandadditive.com Feed Efficiency and Animal Performance Dietary Fibres Used in Animal Feed

Publisher Muhammed Akatay [email protected] Responsible Manager Özlem Akatay [email protected] Editor-in-Chief Derya Yıldız [email protected] Editors Burak Varol Zeynep Demirkaya [email protected] Communication & Marketing Lisa Atakul [email protected] Design Alper Kandemir [email protected] Web Design Caner Cem Pulat [email protected] Circulation and Data Responsible Amine Şengün [email protected] Ataturk St. Metropol Istanbul Ste. Block C1, No:376 Atasehir, Istanbul/TURKEY Phone: +90 850 220 5064 E-Mail: [email protected] Web: www.feedandadditive.com Publication Type: Periodic (Monthly) EDITOR The pressure on farmers who make their living from animal production is increasing day by day. Because on the one hand, they have to meet the increasing demand for animal food on a global scale, and on the other, they have to switch to sustainable methods that will minimise their environmental impact. However, this is a highly contradictory and challenging situation. One of the key strategies to overcome these challenges is to improve feed efficiency. Feed efficiency is defined as the ability of an animal to convert feed into body weight, milk, eggs or other products, and plays an important role in determining the profitability, sustainability and overall performance of farms. The metric used to measure feed efficiency is Feed Conversion Ratio (FCR). Optimising the FCR means that less feed is required to produce the same amount of product, which means lower greenhouse gas emissions and reduced pressure on land and water resources. To summarise, in an era of rising feed costs and increasing concerns over resource use, optimising feed efficiency is crucial to reduce operating costs and improve sustainability. So how can feed efficiency be improved? According to experts, improving feed efficiency requires a holistic approach involving genetics, nutrition and management practices. Selecting animals with superior genetic characteristics for feed conversion; tailoring the feed diets to the needs of the animal, taking into account factors such as age, weight and production period; using components such as high-quality proteins, fats and carbohydrates in the right balance; and using appropriate herd health management, including optimum housing conditions, are listed among the main ways to increase productivity. Feed additives are another efficiency factor that should be carefully considered in terms of nutrition. If used appropriately, feed additives can significantly improve feed conversion ratio by enhancing digestion, nutrient absorption and overall animal health. This will translate into increased production performance, farm efficiency and profitability. Going forward, it is clear that feed efficiency will continue to be a cornerstone of the industry's success, shaping the future of animal farming in ways that benefit producers, consumers and the planet. And yes, efficiency is the first step to a sustainable future. Keep reading our magazine to learn more about the topic. Enjoy your read… Can efficiency be the first step to a sustainable future? Derya YILDIZ © Three Plus Media | All rights reserved. Reproduction, in whole or in part, is prohibited without the written permission of the publisher. *DISCLAIMER: All views and ideas expressed in articles published in the magazine reflect the point of views of the author(s), not that of the Editor-in-Chief, Editors, Editorial Board or Publisher of Feed & Additive Magazine. The Editor-in-Chief, Editors, Editorial Board and Publisher assume no responsibility or liability in such cases. The publisher does not give any warranty and representation to the accuracy or completeness of the contents and data published in the magazine. All responsibility of the contents, articles and information published in the magazine belongs to the authors. The publisher and the authors cannot be held responsible for any damages resulting from the use of the whole or part of the content of the magazine. feedandadditive

Assisting feed formulators and nutritionists in reducing Carbon Footprint of their feed Selko IntelliBond is the first source of improved trace mineral nutrition to have its carbon footprint verified within an LCA and is now listed within the branded GFLI global feed ingredients listing! By utilizing data from the GFLI database, feed manufacturers can independently determine the carbon footprint of their feeds and provide alternative formulation options. This enables the industry to make informed choices that lower the environmental impact of their feed purchases, aligning with sustainability goals set by retailers and others. IntelliBond, the first improved trace mineral source listed in the global GFLI database Learn more, visit www.selko.com

CON T E N T S 24 ISSUE FOCUS FEED EFFICIENCY & ANIMAL PERFORMANCE 40 IMPROVING BROILER POULTRY EFFICIENCY AND DRIVING SUSTAINABLE CHICKEN Dr. Harriet Walker, Alltech 47 FEED EFFICIENCY, A COMPLEX MULTIFACTORIAL CONCEPT IN NUTRITION Aurélie Montagnon, Orffa Additives BV 52 THE POTENTIAL ROLE OF TMAO IN MITIGATING FISH HEALTH CHALLENGES DURING WINTER Marianne Nergård, Aker QRILL Company 55 SEAWEED: A SUSTAINABLE SOLUTION FOR FEED EFFICIENCY Rafaela Kava, Ocean Harvest Technology 60 NEW CHALLENGES CALL FOR A FRESH WEANING STRATEGY FOR PIGLETS Maïwenn Bourdoulous, Adisseo 66 OPTIMIZING BROILER CHICK PERFORMANCE BEFORE THEY HATCH Anna Fe Rose Perino, Novus 68 THE ROLE OF FEED ADDITIVES IN IMPROVING ANIMAL PRODUCTION PERFORMANCE Henning Gerstenkorn, Ohly 70 HARNESSING ENDOLYSINS FOR FEED EFFICIENCY AND ANIMAL PERFORMANCE Dr. Kane Miller, Axitan 44 BOOSTING BEEF PROFITS WITH LIVE YEAST SUPPLEMENTATION Dr. Melinda Culver & Andrea Remmersmann, Biochem 26 BOOST DAIRY PERFORMANCE WITH RUMEN-PROTECTED CHOLINE Sion Richards, Balchem ANH 30 TRYPTOPHAN AND ITS FUNCTIONALITY IN LAYING HENS Dr. Eliane Silva, CJ BIO Brazil 34 SUSTAINABLE DAIRY FARMING WITH THE HELP OF YEAST PROBIOTICS Maxime Briche & Erika Paiva, Phileo by Lesaffre

CON T E N T S Hill’s Pet Nutrition enters fresh pet food category 112 Meatly officially launches cultivated pet treats in UK 107 New study focuses on role of peptides influencing food intake in chicks 10 VIV Asia to focus on sustainable solutions in 2025 19 Nutreco obtains grant to develop on-farm solutions 17 NEWS 78 FEED INNOVATIONS: A GLIMPSE INTO THE FUTURE OF POULTRY NUTRITION Yann Fournis, Cargill 82 HOW WILL THE U.S. OVERCOME ITS DEPENDENCY ON CHINA FOR FEED ADDITIVES? André Magrini, Agribusiness Consultant 88 OTTEVANGER BRINGS THE LARGEST INVESTMENT IN I'ANSON'S 125-YEAR HISTORY TO LIFE Rob Hinten, Ottevanger Milling Engineers 91 DAIRY FARMER’S STARTUP IS SPROUTING UP AND SPARKING INTEREST Jennifer Bingham, California Dairy Cares TECHNOLOGY 94 BEYOND WASTE: HOW RENDERING DRIVES SUSTAINABILITY IN ANIMAL AGRICULTURE Jose Ramirez, Anitox ARTICLE INTERVIEWS ADVERTORIAL MARKET REPORT BETATRACE®: BETAINE GOES METAL! By Biochem 73 DIETARY FIBRES USED IN ANIMAL FEED - GLOBAL MARKET STATUS 96

6 FEED & ADDITIVE MAGAZINE March 2025 The feed sector is at a turning point. Global developments are reshaping the way we produce animal nutrition, bringing both challenges and opportunities. The war in Ukraine has disrupted grain markets, exposing Europe’s reliance on external suppliers, while trade restrictions in major economies like China and the US are altering global supply chains. Meanwhile, we face the implementation of ambitious EU sustainability regulations, increasing the administrative burden on businesses. Closer to home, Belgian feed producers and farmers are navigating their own set of challenges. The Flemish nitrogen crisis has resulted in strict environmental policies that require significant adaptation, while rising production costs and fluctuating commodity prices add further uncertainty. In this changing environment, sustainability must go beyond environmental goals: it must also secure economic resilience and food security. As the voice of the Belgian feed sector, BFA plays a central role in this transition. Representing over 96% of the Belgian compound feed market, our members supply livestock farms across the country. Belgium is home to a highly efficient and export-oriented livestock sector, and the feed sector is a key enabler of its success. With a strong focus on sustainability, innovation, feed safety and regulatory compliance, BFA strives for the Belgian feed sector to remain competitive while embracing the challenges of the future. BALANCING RESPONSIBLE SUPPLY CHAINS WITH REGULATORY COMPLEXITY One of the biggest challenges facing the feed sector today is securing stable and responsible supply chains in a time of growing trade restrictions and regulatory demands. For example, BFA and its members are fully committed to deforestation-free supply chains, but the complexity of compliance is raising serious concerns. Belgium has consistently ranked among the top European countries for purchasing certified sustainable soy. Through sector-wide initiatives, Belgian feed producers have proactively committed to high sustainability standards, reducing environmental impact while supporting responsible farming abroad. However, the introduction of the EU Deforestation Regulation (EUDR) adds new layers of complexity that could disrupt well-established sustainability efforts. While the regulation’s goal - preventing deforestation - is essential, its practical implementation remains unclear. Key details, like traceability requirements and enforcement procedures, are still vague, making it difficult for businesses to fully prepare. Without careful planning, these new rules could unintentionally weaken sustainability efforts. Supply chains could shift away from certified sustainable sources, not because of environmental concerns, but simply due to practical difficulties. Feed availability could decrease, while costs go up – putting extra pressure on farmers and producers. That’s why BFA is actively working with suppliers, policymakers, and international partners to ensure Navigating sustainability in a changing world: BFA’S COMMITMENT TO RESILIENT AND RESPONSIBLE FEED Katrien D’hooghe Managing Director Belgian Feed Association - BFA LEAD ARTICLE

FEED & ADDITIVE MAGAZINE 7 March 2025 that sustainability policies remain effective, practical, and economically realistic. SUSTAINABILITY THROUGH COOPERATION With global trade under pressure, local solutions are more important than ever. Belgium already has a strong foundation in circular feed production, with nearly half of all feed ingredients derived from co-products of the food, agricultural, and biofuel industries. Instead of letting valuable resources go to waste, these co-products are reintegrated into highquality animal feed, reducing the need for virgin raw materials while lowering environmental impact. BFA is fully committed to expanding circular feed practices even further. Increasing the use of coproducts, alternative proteins, and innovative feed formulations will help reduce dependence on imports and build a more resilient food system. At the same time, circularity fits perfectly within broader European sustainability goals, supporting the transition to a lowimpact agricultural sector. Beyond circularity, new protein sources may offer alternatives for sustainable feed. Alternative proteins, insects, single-cell proteins, and algae-based feed ingredients are slowly gaining traction as substitutes for traditional protein sources. However, for these innovations to become mainstream, regulations must encourage, rather than hinder, their adoption. BFA supports science-driven solutions that enhance feed efficiency, reduce emissions, and keep feed affordable for farmers. The challenges facing the feed sector cannot be solved individually. At BFA, we strongly believe that cooperation is key. At national level, we work closely with sector stakeholders and government bodies to align sustainability efforts with the realities of feed production. Open dialogue between policymakers and sector representatives is essential for developing policies that are both effective and feasible. At the European level, BFA actively contributes to discussions within FEFAC among others, making sure that Belgium’s feed sector has a strong voice in EU policymaking. As regulations evolve quickly, it is crucial that the needs and insights of feed producers are taken into account when shaping new laws. On a global scale, BFA continues to engage with international partners to share best practices and develop cooperative solutions. Sustainability is a worldwide challenge, and cross-border collaboration is necessary to create a responsible and resilient food system. BUILDING A SUSTAINABLE AND RESILIENT FUTURE Sustainability in the feed sector must be both achievable and economically viable. Through its Sustainability Charter 2.0, BFA remains committed to low-impact feed production, responsible sourcing, and circular economy principles. But the road ahead must be carefully managed. Regulations must be feasible. Overregulation can slow down innovation and put too much pressure on businesses. Feed producers and farmers need a regulatory framework that supports progress and long-term security instead of creating extra obstacles. Despite geopolitical tensions and challenges for free trade, it remains important to be proactive and explore new opportunities for sustainable trade, capitalising on the investments of compound feed manufacturers in innovative animal nutrition solutions to enhance the resilience and competitiveness of the Belgian agricultural sector. By promoting innovation, strengthening partnerships, and advocating for practical solutions, BFA is working toward a feed sector that is resilient, responsible, and ready for the future.

NEWS 8 FEED & ADDITIVE MAGAZINE March 2025 Adisseo recently welcomed 26 key customers from across Europe (EU) and the Middle East & Africa (MEA) for an exclusive event focused on the future of dairy nutrition and of the new construction of MetaSmart® production capacity. From January 28th to 30th, industry leaders, including feed mill managers and dairy nutritionists, gathered in Burgos, Spain, to gain firsthand insights into Adisseo’s latest investment: a new state-of-the-art plant dedicated to producing HMBi, the active ingredient in MetaSmart®. Adisseo states that this new facility, integrated into the existing Burgos platform—already home to the production of OH-methionine: Rhodimet® AT88—reinforces the company’s commitment to serving dairy farmers worldwide with innovative and sustainable solutions. With global demand for dairy products, particularly dairy fat and butter, continuing to rise, farmers and nutritionists are looking for more efficient ways to increase milk production while reducing environmental impact. The industry is shifting away from excessive protein feeding, and Adisseo points out that it has been at the forefront of this transformation for over 30 years, pioneering amino acid (AA) balancing as a key strategy. According the statement, MetaSmart® provides a highly effective methionine source for ruminants. By lowering protein levels in dairy cow diets and supplementing with targeted methionine solutions like Smartamine® M and MetaSmart®, farmers can: • Increase milk production and components. Read more>> Adisseo’s new facility to meet dairy industry needs in late 2025 Amlan® International, the animal health business of Oil-Dri® Corporation of America, met with representatives from the swine industry at the XXXI AMVECAJ International Congress, which kicked off on February 5, 2025 in Tepatitlán de Morelos, Jalisco, Mexico. Organized by the Association of Veterinary Doctors Specialists in Pigs of Los Altos de Jalisco (AMVECAJ), this annual event was a cornerstone for the swine industry in Mexico and beyond, attracting leading experts and producers from across the globe. This year’s theme, “Efficient and Healthy Farms, Profitable Results”, highlighted the importance of integrating innovation, animal welfare, and operational excellence to drive industry growth. Amlan, in partnership with KOFARM, showcased its portfolio of natural mineral-based feed additives and technical expertise at this year’s congress, where attendees can explore how Amlan’s solutions align with the event’s theme. With Mexico producing approximately 43 million metric tons of animal feed in 2023—15% of which was dedicated to swine—there is a growing need for innovative solutions to support efficient and sustainable production, Amlan pointed out. “The theme of this year’s AMVECAJ Congress speaks directly to the heart of what we do at Amlan,” said Dr. Robin Jarquin, Regional Director, LATAM at Amlan International. “By focusing on gut health and production efficiency, we help producers achieve the profitability they need while maintaining the health and sustainability. Our partnership with KOFARM further strengthens our ability to deliver these benefits to the Mexican market.” Read more>> Amlan showcases innovative feed additives in Mexico

NEWS FEED & ADDITIVE MAGAZINE March 2025 9 An innovator in nutrition and health, dsm-firmenich announced the sale of its stake in the Feed Enzymes Alliance to its equal partner Novonesis, one of the global leaders in biosolutions, for €1.5 billion. The dsm-firmenich activities to be sold under this transaction to Novonesis represented in 2024 approximately €300 million in total annual net sales, according to the announcement. Novonesis will continue a long-term commercial relationship with the Animal Nutrition & Health business, for the re-sale of its feed enzymes through the Animal Nutrition & Health world-class premix network. dsm-firmenich expects to receive approximately €1.4 billion net in cash, after transaction costs and capital gains tax, and anticipates a book profit on the transaction to be recognized upon closing. Through a unique alliance formed more than 25 years ago, dsm-firmenich and Novonesis have jointly developed one of the industry’s most competitive, comprehensive and innovative feed enzymes portfolio for the animal feed markets. At dsm-firmenich, the feed enzymes business is currently part of the Animal Nutrition & Health business unit, which itself will be separated from the group to operate under new ownership, as announced in February 2024. In the context of this separation, the partners evaluated the future of their alliance and concluded that unwinding the alliance would be strategically beneficial for both parties. Read more>> dsm-firmenich to sell stake in Feed Enzymes Alliance to Novonesis Selko, Nutreco’s feed additive brand, shared its findings from its 2024 Global Mycotoxin Review at the webinar it hosted. Analysis of more than 86,000 samples from 47 countries - including grains, byproducts, protein meals, silages and TMRs - offers insights on the presence and concentrations of key mycotoxins known to adversely affect livestock and poultry (animals). The review also outlines potential mycotoxin risk for animals in 2025. Selko shared the recorded webinar findings from the review and outlook on its website. The mycotoxin data on raw materials and complete feed samples available in Trouw Nutrition’s Global Database was used to prepare the 2024 Global Mycotoxin Review. The report focused on “Big 6” mycotoxins, Deoxynivalenol (DON), T-2/ HT-2 Toxin (T2HT2), zearalenone (ZEA), fumonisins (FUM), aflatoxin (AFLA), and ochratoxins (OCHRA), as these are often analysed at feed mills using rapid analytical tools and extensive research is available on their adverse effects in animals. According to the findings, globally, ZEA was the mycotoxin most detected in 2024 samples, with 66% of samples showing a detectable level. Additionally, DON (58%), FUM (54%), and T2HT2 (56%) were found in more than half the samples tested. DON and FUM had the highest average concentrations as well as the highest median concentrations. Read more>> Selko reveals 2024 Global Mycotoxin Review findings

NEWS 10 FEED & ADDITIVE MAGAZINE March 2025 Angel Yeast officially completed the topping out of the main plant for the industrial yeast protein production project at Baiyang Yichang, China, which will boost an annual output of 11,000 tons, a milestone of Angel Yeast's sustainable protein development strategy. The company states that it is committed to building a sustainable future with innovative fermentation technologies and advanced biomanufacturing capabilities to advance the development of global alternative proteins and new sustainable food products. Traditional protein production, from cereal and legume cultivation to dairy farming, is time-consuming and may struggle to meet future demands for quantity, quality, and sustainable supply. Therefore, there is an urgent need to innovate large-scale, low-cost, and high-quality protein production methods. Angel Yeast explained that it has achieved the breakthrough to extract proteins from yeast, only taking hours, boosting production efficiency significantly. To meet the growing market demands, the company is expanding production capacity and the 11,000-ton production line is expected to be put into operation in 2025. Read more>> Angel Yeast increases yeast protein production The poultry industry plays a vital role in the global food supply and is a cornerstone in the agricultural sector. With poultry meat and eggs being the most efficient and widely consumed animal proteins, advancing research to increase poultry productivity is crucial. The productivity of meat and eggs in chickens is widely dependent on food intake, and it is therefore imperative to investigate how feeding mechanisms are regulated within chicks. To explore this further, Dr. Takaoki Saneyasu, an Associate Professor at the Graduate School of Agricultural Science, Kobe University, conducted a comprehensive review of recent research on the physiological mechanisms governing food intake in poultry. This study was made available online on April 26, 2024, and published in Volume 61 of the Journal of Poultry Sciences. “Broiler chickens are genetically selected for rapid growth and meat yield, yet their overconsumption of food leads to fat accumulation, which often results in poultry waste," says Dr. Saneyasu. “Understanding the mechanisms of food intake is, therefore, crucial for improving feed efficiency and reducing waste." The regulation of food intake in living beings is a complex process. Although there is a lot of research on the food intake regulations in humans, the mechanisms in chickens differ from those of mammals like humans in some factors. "Many factors, such as hormones, nutrients, and neurological signaling, control food intake in living beings. Some of these factors differ between humans and poultry,” adds Dr. Saneyasu. He reviewed various factors, including neuropeptides, such as adipokines, neurosecretory proteins GL and GM, and cellular signaling, to determine how each of these factors impacts the food consumption in chicks. Read more>> New study focuses on role of peptides influencing food intake in chicks

NEWS FEED & ADDITIVE MAGAZINE March 2025 11 Looking to combine performance and health without compromise in post-weaning piglets? Are you sure your piglets achieve their full potential after weaning? Discover our nutritional approach for post-weaning piglets to ensure maximum success. DISCOVER MORE www.adisseo.com

NEWS 12 FEED & ADDITIVE MAGAZINE March 2025 Chipotle Mexican Grill announced it is making minority investments in CH4 Global, a company aiming to impact climate change at scale via methane-reducing innovations, and Plantible, a company harnessing the power of Lemna, an aquatic plant, to create what could prove to be the world's most functional plant-based protein. Introduced in 2022, Cultivate Next makes early-stage investments into strategically aligned companies that further Chipotle's mission to Cultivate a Better World and help accelerate the company's longer term growth plans to operate 7,000 restaurants in North America. CH4 Global is on a mission to deliver gigaton-scale emissions reductions over the next decade using whole, dried Asparagopsis seaweed targeting livestock methane. The company's flagship product, Methane Tamer™, is a feed additive that leverages Asparagopsis, with a goal of reducing methane emissions in cattle by up to 90%. Chipotle's investment will help CH4 Global scale production of Methane Tamer to meet burgeoning global demand for natural solutions to mitigate methane emissions from the world's 1.5 billion cattle. According to the statement, in addition to slashing methane output, Asparagopsis may reduce the feed energy lost to methane production inside the rumen area of their stomachs. This means that cattle could get more energy and nutrition from the same amount of food, which would help them grow or produce milk more efficiently while reducing their environmental impact. “As we all work toward the goal of minimizing global greenhouse gas emissions, it's vital for us to invest in companies like CH4 Global that are engineering scalable solutions to reduce harmful global emissions," said Christian Gammill, Cultivate Next Fund Manager. "Our investment in CH4 Global will help the team scale production of Methane Tamer™ to meet its current outstripped demand.” Read more>> Chipotle invests in aquatic plant-based technologies Alltech, one of the global leaders in biotechnology, released its complete 2024 U.S. Harvest Analysis report. The comprehensive final report shows that a combination of heavy early-season rains and late-season droughts has created distinct challenges for crop producers in the United States and indicates that overall risk is moderate to high. “The trend for corn grain and corn silage is somewhat higher across all regions of the U.S. than it was for 2023,” said Dr. Max Hawkins, Global Technical Support for the Technology Group at Alltech. “This increase in risk is due to the occurrence and levels of type B trichothecenes primarily, but zearalenone and fumonisins are also included in the increase, particularly in the Eastern U.S. The result is an increased pressure on animal health and performance that producers will need to monitor moving forward to maintain a proactive mycotoxin management program.” The final mycotoxin risk will ultimately depend on the animal species and groups being fed and the mycotoxin concentrations and combinations in the finished diet. Mycotoxins, which are natural substances produced by molds and fungi, are more prevalent — and more of a problem in agriculture — than ever before. More than 95% of crops today are contaminated with at least one mycotoxin, and usually with two or more. Because these toxins are difficult to detect, they can cause significant damage to animal health before producers even realize they are present. Read more>> Harvest analysis shows rising mycotoxin risks for corn

NEWS FEED & ADDITIVE MAGAZINE March 2025 13 Nor-Feed announced the publication of a new peer-reviewed study in the journal Animals, highlighting the positive effects of Nor-Spice AB®, a standardized natural citrus extract (SNCE), on broiler chickens. The research demonstrates that supplementing broiler diets with SNCE leads to notable improvements in growth performance, gut health, carcass quality, and overall animal welfare. In this study, broiler chickens receiving a diet supplemented with 250 g/T of SNCE exhibited significant enhancements in several key areas compared to a control group: • Improved final body weight, European Efficiency Index, and carcass quality in broilers; • Enhanced welfare indicators, including a reduction in Footpad Dermatitis occurrence; • Better gut health, with measurable improvements in putrefactive shortchain fatty acids and gut integrity. This study adds to the growing body of evidence supporting the efficacy of Nor-Spice AB® in enhancing animal performance. Its natural composition makes it an excellent choice for producers seeking effective and sustainable feed additives, according to the company’s statement. Nor-Spice AB® is composed of natural citrus extracts and is standardized in citroflavonoids and pectic-oligosaccharides (POS). Nor-Feed points out that these components stimulate the growth of Acidophilic bacteria, leading to improved feed efficiency and animal growth. Read more>> New study highlights effect of Nor-Feed’s citrus extract additive in broilers' diets Sangrovit® supplementation led to improved feed efficiency and rumen stability in heat-stress conditions. Based on science Numerous studies show that the true value of Sangrovit® unfolds in periods of increased stress. Feed change, medical treatments, heat stress – the challenges are as manifold as our animals and production systems. Scan the QR code and read more or contact our experts: [email protected] | www.phytobiotics.com Estrada-Angulo et al, 2016

NEWS 14 FEED & ADDITIVE MAGAZINE March 2025 The Institute for Feed Education and Research (IFEEDER) initiated a research project to analyse the potential impacts that vitamin and amino acid supply chain disruptions could have on livestock health and food security. This project aims to identify the critical supply thresholds and inclusion rates at which animal health and livestock production would be adversely affected from shortages of key diet nutrients. The research will be completed by Decision Innovation Solutions (DIS), working in collaboration with Lobo Consulting Solutions. “The last few years, feed and ingredient manufacturers have faced a volatile supply chain, amid geopolitical tensions, labor disputes and more. To proactively plan for the future, IFEEDER’s new research project will work to understand where the U.S. industry is vulnerable so that they can look for solutions now before livestock and poultry production or U.S. food security is adversely affected,” said Lara Moody, IFEEDER Executive Director. The study will employ advanced modelling techniques to simulate varying levels of ingredient availability, assessing the downstream effects on livestock and poultry production. Areas of focus include analysing vitamin and amino acid deficiencies' impact on growth rates, feed utilization efficiency, protein output and overall productivity. The research will also consider health indicators such as mortality rates, reproductive success and changes in lean meat yield. Read more>> IFEEDER researches impacts of vitamin and amino acid supply issues The Global Feed LCA Institute (GFLI) certified and listed Selko® IntelliBond® Z, C and M within its new, branded feed ingredients database. The listing follows GFLI’s comprehensive internal review of IntelliBond’s technical dossier, including a recently completed LCA defining the carbon footprint for each of its trace mineral products. For feed formulators and nutritionists, the listing of Selko® IntelliBond® Z, C and M in the GFLI database offers assurance that the total carbon values per ton of product listed for IntelliBond Z, C and M have been independently verified to comply with all industry accepted sustainability standards. External verification of a product’s sustainability status is especially important when it comes to ensuring that the product is in full compliance with all environmental statutes. Only then can industry professionals have confidence that the ingredients they select for their formulation have the required positive environmental impact. The verification process utilized by GFLI is designed to ensure that ingredients listed within its proprietary, global database have undergone a rigorous review by industry professionals to ensure that published values are compliant with all environmental statutes. A key part of the GFLI certification process involved a comprehensive review of the Selko IntelliBond LCA for individual IntelliBond products (Z, C and M). The LCA development process involved an extensive review of all raw ingredients, energy consumption, water utilization and recovery, and logistics to arrive at a total amount of CO2eq produced per ton of finished product. Read more>> Selko IntelliBond added to GFLI feed ingredients database

NEWS FEED & ADDITIVE MAGAZINE March 2025 15 Gut health is more than a gut instinct. Improving bird productivity through clean feed. Get the study today. www.anitox.com/broiler-performance Kormotech Group of Companies, one of Ukraine's largest pet food manufacturers and one of the world’s top 50 producers in the industry, commenced construction of its second factory in Lithuania. The company has announced it is investing €60 million in this project, further strengthening its presence in the European market. The official groundbreaking ceremony took place in Kėdainiai. The company currently operates three factories: two in Ukraine and one in Lithuania, opened in 2020. The new 19,500-square-metre production, warehousing, and administrative facility will triple production capacity in Lithuania – from 22,000 to 60,000 tonnes per year. Upon completion, Kormotech explained it will produce 61% of its total output in wet pet food in Kėdainiai. “Today we have started a strategically important stage that will allow us to continue our expansion in Europe and the world. The new factory will triple our production capacity in Lithuania, thus significantly boosting our goal of becoming one of the top 30 players in the global pet food market. We see Lithuania as a reliable partner that allows us to unlock and grow our potential in global markets, so we are pleased to have chosen this country and to be able to increase our operations here significantly,” Rostyslav Vovk, Chairman of the Board and Co-Owner of the Kormotech Group of Companies, stated at the event held to mark the groundbreaking for the factory. Read more>> Kormotech to expand operations in Lithuania with second factory

NEWS 16 FEED & ADDITIVE MAGAZINE March 2025 International Flavors & Fragrances Inc. (IFF) unveiled its newly redesigned corporate website, www.iff.com, marking a significant leap in scale, performance and commitment to top-tier digital experiences. The revamped site offers a visually captivating and engaging journey, highlighting IFF’s leadership and the value it delivers across all the markets it serves. “The IFF site represents the full breadth of our portfolio and the value we offer through our technology and innovation,” said Deb Borg, Executive Vice President and Chief Communications, Human Resources, and Diversity & Inclusion Officer. “It is a powerful tool for increasing our brand recognition, strengthening our customer relationships and attracting world-class talent.” The new website features improved navigation, fresh content, enhanced lead-generation tools, and CRM strategies all within a responsive and modern design. Visitors can easily access key information and resources. The new comprehensive media center provides diverse perspectives on the company and easy access to business-specific content. Additionally, an expanded sustainability hub—along with careers, history, insights, and science sections—offers deeper context about the company, showcasing its expertise. Read more>> IFF launches its revamped website Packaged Feeds, one of the leaders in innovative food waste-to-resource solutions, partnered with FreezeM to integrate the company’s Breeding-as-a-Service technology into its Black Soldier Fly (BSF) operations. By selecting FreezeM’s PauseM® product, Packaged Feeds underscores the unmatched operational efficiency and protein quality that PauseM® delivers, validated through extensive field pilot testing, according to the announcement. FreezeM stated that PauseM®, its flagship product, contains suspended BSF neonates with a 14-day shelf life, eliminating the need for in-house BSF breeding. This synergy with Packaged Feeds’ advanced rearing technology establishes a scalable, high performance insect farming process, driving the company’s transition from proof-of-concept to large-scale operations. FreezeM will initially supply PauseM® from its state-of-the-art facility in Germany, ensuring seamless integration and robust support as Packaged Feeds scales its efforts. Building on its expertise in organic surplus co-product solutions, Packaged Feeds has successfully developed a pioneering BSF rearing and processing technology based on proprietary modular rearing units that can be rapidly deployed near organic co-product sources. These modular insect bioconversion farms provide efficient, scalable and adaptable solutions tailored to diverse operational setups. In 2025, Packaged Feeds explained it is planning to deploy its first production site, with the capacity of treating 15,000+ tons/organic surplus co-products per year. By the end of 2026 the company expects to operate 6 such sites in the UK, treating over 100,000 tons of surplus co-products/year. Read more>> Packaged Feeds and FreezeM partner for zero-waste BSF farming

NEWS FEED & ADDITIVE MAGAZINE March 2025 17 One of the global leaders in animal nutrition, Nutreco received an OPZuid grant to collaborate with Dutch dairy farmers on reducing nitrogen emissions. This funding enables the development of on-farm solutions fit for the Netherlands' environmentally demanding dairy sector, preparing it for future global challenges. The project, officially named: “Realising the maximal reduction of nitrogen emissions achievable through dietary means within the dairy herd of Noord-Brabant” is a collaboration between Nutreco’s livestock feed business, Trouw Nutrition and Nutrivice B.V. The project received a grant from Dutch subsidiary programme OPZuid (a subsidiary programme for the three southern Dutch provinces Noord-Brabant, Limburg and Zeeland, backed by EU funding), for a period of 4 years. The Netherlands is among the countries with the most geographically dense nitrogen emissions in the world, where 45% of emissions originate from the agricultural sector. Noord-Brabant is province with the highest livestock density in the Netherlands. Within the consortium, Nutreco delivers extensive knowledge and an R&D base (Trouw Nutrition R&D), and Nutrivice functions as an indispensable link to dairy farmers and their daily operations. Trouw Nutrition R&D has years of strategic focus on nitrogen (N) efficiency to address the global importance of this topic as limiting factor for efficiency, profitability and land use in tropics (Brazil and India) and North American dairy and beef business, while being critical to dairy sustainability in Europe. Read more>> Nutreco obtains grant to develop on-farm solutions Superior Animal Feed Solutions We build equipment that just runs. CPM is the world’s leading provider of innovative and automated solutions for new equipment and aftermarket.

NEWS 18 FEED & ADDITIVE MAGAZINE March 2025 Trouw Nutrition, Nutreco’s livestock feed business, will be presenting science-based nutrition and digital tools to help farms and feed mills lower the carbon footprint of their operations, support feed safety, and nurture livestock performance at VIV Asia 2025, 12-14 March. Visitors to stand 2-3736 can see live demonstrations of digital technologies like NIR and life cycle assessment tools, learn about proprietary phytogenic ingredients developed for Nutreco’s Garden of the Future, and explore models and tools to support distinct phases of poultry and swine production. Trouw Nutrition shared the following highlights of its presence at VIV Asia: Developed by scientists at Nutreco’s Garden of the Future, Fytera Perform is a PhytoComplex that supports specific physiological and metabolic processes inside the bird. Studies around the world have shown that these novel, plant-based functional ingredients can improve feed conversion ratio and overall poultry performance. This natural approach to developing performance-enhancing feed additives responds to marketplace demand for more sustainable poultry production. A NutriOpt demonstration zone will spotlight several digital tools to support stakeholders across the value chain and showcase Trouw Nutrition’s commitment to feeding the future. MyFeedPrint calculates the environmental effects of feed ingredients and complete feeds to help formulators reduce the environmental footprint of feed production. Data generated by MyFeedPrint can help implement practices to reduce carbon emissions and enhance the transparency of feed production. Read more>> Trouw Nutrition to showcase its innovations at VIV Asia 2025 Forever Feed Technologies announced the completion of the FFT Innovation Center on River Ranch Farms in Hanford, California, USA, housing the world's largest Automated Sprouted Grain (FFT-ASG™) feed mill. The Innovation Center feed mill produces fresh ASG daily to supplement feed rations for dairy and beef cattle, using a small fraction of the water that's needed for field-grown alfalfa. The company pointed out that the FFT Innovation Center feed mill is the first phase of a commercial scale version that is targeted to grow up to 50 tons of ASG per-day, reducing on-farm risks due to droughts and severe weather conditions, and will move operators closer to their 2030 Net-Zero sustainability goals. The design of the FFT Feed Mill began in 2022 when Forever Feed engaged JR Automation, a Hitachi, Ltd. company, to help integrate time-test material handling technology with FFT's patent pending indoor growing protocols. According to the announcement, the robust capabilities of material handling systems and FFT's proprietary methods make the feed mill dependable enough to support the high demands of supplying fresh feed yearround on major dairy and beef operations. Read more>> Forever Feed completes world's largest automated sprouted grain feed mill

NEWS FEED & ADDITIVE MAGAZINE March 2025 19 VIV Asia 2025, the premier international trade show for the animal protein production and processing industry is set to return this year in co-location with Meat Pro Asia and Horti Agri Next (HAN) Asia, with an expanded focus on sustainable solutions. This year’s edition, to be held in Bangkok, Thailand from March 12-14, will feature a series of high-level seminars that will address pressing challenges in modern livestock production, including disease prevention, regenerative agriculture, and biosecurity. These seminars will provide a platform for in-depth discussions, knowledge-sharing, and collaboration among industry professionals, all with the shared goal of shaping the future of animal farming. With over 150 curated sessions led by 300 industry experts, a major emphasis of VIV Asia 2025 will be on disease prevention and biosecurity, where speakers will present cutting-edge strategies for controlling infectious diseases, mitigating risks, and enhancing farm biosecurity to ensure resilient livestock production. The seminars will offer insights into the latest scientific developments, policy frameworks, and technological innovations designed to protect animal health and minimize the risk of disease outbreaks. Another key focus will be on regenerative agriculture within animal farming, with thought leaders exploring sustainable farming practices that enhance soil health, foster biodiversity, and optimize resource efficiency. Discussions will highlight the economic and environmental benefits of regenerative approaches, along with real-world case studies that demonstrate their effectiveness. Read more>> VIV Asia to focus on sustainable solutions in 2025 Supplant D Optimizing broiler performance • Improving feed intake. • Better feed conversion. • Reduced mortality. • Higher ROI agrimprove.com M-prove

NEWS 20 FEED & ADDITIVE MAGAZINE March 2025 A newly released study conducted at the University of Las Palmas de Gran Canaria, in collaboration with Aker ǪRILL Company and the University of Stirling, highlighted the benefits of dietary krill meal inclusion for gilthead sea bream (Sparus aurata) juveniles. This study was funded by AǪUAEXCEL3.0, under the TNA program. The study demonstrates that krill meal can improve nutrient utilization, optimize feed efficiency, and boost resilience against oxidative stress, contributing to a more effective aquafeed. The study reveals that including krill meal in the diet significantly enhances fish health and stress tolerance, particularly during crowding challenges. This aligns with previous aquafeed trials with krill meal, reinforcing the ingredient’s potential to drive both sustainability and efficiency in the aquaculture industry. Gilthead sea bream is a highly valued species for aquaculture. However, crowded farming conditions often lead to oxidative stress, which affects fish health and growth. While traditional fish meal has been the cornerstone of aquafeeds, its fluctuating supply and cost are driving a greater need for more sustainable alternatives. Read more>> New study highlights benefits of dietary krill meal for gilthead sea bream The latest research from BioMar shed light on the aquafeed challenges associated with waterborne feeding systems. This new feeding system technology is gaining traction amongst salmon farmers for its potential to reduce energy consumption, microplastic pollution, and sea lice exposure. While these systems offer promising benefits, BioMar has identified specific factors contributing to nutritional loss in feed delivered through submerged systems. According to the statement, internal trials have shown that several factors can drive nutrient degradation. These factors vary in intensity and underline the complexity of creating an aquafeed that performs consistently under the unique conditions of waterborne feeding. Drawing from extensive experience with the ORBIT product range and POWER grower diets, BioMar has made significant progress in understanding how raw materials and production processes impact feed performance in submerged environments. Early validation trials conducted on commercial systems have delivered promising results, giving BioMar a strong foundation for further development. “Through our research, we have a better understanding of the complex dynamics of waterborne feeding,” said Ewan Cameron, Product Marketing Manager of the Grower Category for BioMar. “These insights allow us to enhance our feed formulations and production techniques to reduce nutrient loss significantly.” Read more>> BioMar investigates ideal aquafeed for waterborne feeding

NEWS FEED & ADDITIVE MAGAZINE March 2025 21 AB Vista, a global animal nutrition technology company, will showcase how its gut health findings and nutritional solutions can support animal producers at VIV Asia 2025, taking place from 12-14 March at the IMPACT exhibition centre in Bangkok, Thailand. The company will host two technical seminars at the event, providing insights on key gut health biomarkers in monogastrics and the role of in-feed resin acids in improving animal performance and welfare. AB Vista’s Head of Global Technical, Dr. Gilson Gomes, will delve into the benefits of natural resin acids in animal production. Exploring the science behind infeed resin acids, he will examine how their use can support gut integrity and improve resilience and performance, naturally. Dr. Gomes will also share practical insights into application of Progres® - the first and only product in the animal feed market to leverage the power of natural resin acids. The seminar, “Progres: The science behind the use of resin acids to improve animal welfare and performance of animals”, will be on Wednesday 12 March at 1pm THA, in Jupiter 9. In a separate session, Global Services Manager Dr. Virginie Blanvillain will set out how AB Vista has successfully applied advanced microbiome analysis in the field. Read more>> AB Vista to host two technical seminars at VIV Asia Porcine reproductive and respiratory syndrome virus (PRRSV) infection in pigs is economically devastating for the global swine industry. The viral infection leads to reproductive disorder in sows and respiratory problems in infected newborn and growing pigs. Unfortunately, high genetic variability of the virus and differing disease-causing strength or virulence hinders vaccine development and complicates disease management. Not much is known of the factors contributing to viral disease severity or the anti-viral immune responses. But scientists from ChungAng University in Korea uncovered the impact of PRRSV on swine immunity. The scientists used single-cell RNA analysis to reveal key immune mechanisms in lungs of swine infected with PRRSV and revealed changes in immune cell composition in lungs during infection with PRRSV of varying severity. Dr. Jun-Mo Kim, Associate Professor at the Department of Animal Science and Technology, Chung-Ang University, Korea has focused his research efforts on filling this gap in understanding. “Using a PRRSV infection model, our goal is to advance the comprehensive understanding of the infection and response mechanism in order to minimize industrial damage,” shared Dr. Kim. Recently, his group analysed protein-coding RNA transcripts isolated from single cells and fluid collected from lungs of PRRSV-infected pigs. They monitored immune cell alterations triggered by PRRSV strains of varying virulence. This paper was made available online on January 28, 2025 and was published in Volume 16 Issue 1 of Nature Communications. Read more>> Korean scientists explore impact of PRRSV on swine immunity

NEWS 22 FEED & ADDITIVE MAGAZINE March 2025 Cargill and BinSentry formalized a partnership to provide artificial intelligence (AI)-powered sensor technology to help Brazilian producers improve efficiency and control of their animal feed supply chain for healthier pork and poultry, and more profitable operations. The agreement makes Cargill the exclusive distributor in Brazil of BinSentry’s animal feed inventory management platform. It builds on a partnership that began more than four years ago to market the companies’ leading-edge technology across North America to ensure producers, feed mills and their customers get the right feed at the right time, and in the right quantities, for their operations. Integrating BinSentry technology with Cargill’s expertise in sustainable food production will open up exciting opportunities for the Brazilian agrifood sector, said Marcelo Dalmagro, Strategic Marketing and Technology Leader for Cargill Animal Nutrition in South America. “Cargill, a global leader with over 150 years of history, is proud to team up with BinSentry, a growing ag-tech innovator, to bring cutting-edge technology to Brazil that will help producers optimize their operations, increase the competitiveness of Brazilian agribusinesses and strengthen Brazil’s position as a leading exporter of pork and poultry,” pointed out Dalmagro. According to the announcement, BinSentry’s rugged, easyto-install sensors are now monitoring more than 25,000 feed bins for some of the largest swine and poultry producers in the United States and Canada. Read more>> Cargill and BinSentry partner to optimize Brazil’s animal feed supply chains Germany-based DostoFarm GmbH, a manufacturer of innovative solutions based on natural active ingredients for animal and human nutrition, recently revealed that PHYTOsolvan® Liquid, a natural solution that significantly improves well-being and stimulates feed intake by supporting animals' respiratory function, is now halal certified. According to the company, the new Halal certificate underlines DostoFarm's commitment to sustainable and ethical production. According to the statement by DostoFarm, the unique combination of thyme and aniseed essential oils and carefully selected herbal extracts in PHYTOsolvan® naturally supports the respiratory function of animals. The product enhances the palatability of the feed, contributing to better feed intake. In addition, the pleasant odour can help keep the airways clear and improve the odour of the barn. All ingredients in PHYTOsolvan® Liquid, a water-soluble feed supplement that can be easily administered via drinking water, are of natural origin and have been scientifically tested, the company says. According to the statement, thanks to no withdrawal time, PHYTOsolvan® can be used without any restrictions. Read more>> DostoFarm receives Halal certification for PHYTOsolvan product

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