ARTICLE 84 FEED & ADDITIVE MAGAZINE December 2024 fects of a specific lower gut live yeast supplementation, from a Saccharomyces c. boulardii yeast CNCM I-1079 (PROTERNATIVE). The results showed that cows supplemented from 1 month before calving to 2 months after calving show mitigation of the negative consequences of transition at the gut level. The yeast maintained and strengthened intestinal barrier function, and gut integrity and improved the microbiota balance while mitigating the immune response. The yeast also promoted energy allocation towards milk quality while minimizing inflammatory responses. CONCLUDING REMARKS Although dairy cow transition challenges might sound inevitable, an effective management approach goes a long way in mitigating the problems. A holistic solution approach aims to limit inflammation, extract more energy from the diet, and limit lipid mobilization and oxidative stress during the transition period. Proper management of inflammation and maintenance of epithelial integrity during the transition period helps improve cow health and performance, yielding high economic outcomes. Nutritional feed additives such as live yeast are key management solutions that can help, among other management actions, to ensure a smooth transition period in dairy cows. Not all products are available in all markets nor associated claims allowed in all regions. References 1.Abuelo A., Joaquín Hernández., José L. Benedito., Cristina Castillo., 2019. Redox Biology in Transition Periods of Dairy Cattle: Role in the Health of Periparturient and Neonatal Animals. Antioxidants 8, 20. 2.Cobirka M., Vladimir Tancin., Petr Slama., 2020. Epidemiology and Classification of Mastitis. Animals 10, 2212. 3.Goff, J. P. (2008). The monitoring, prevention, and treatment of milk fever and subclinical hypocalcemia in dairy cows. The veterinary journal, 176(1), 50-57. 4.Horst E. A., Kvidera S. K., Baumgard L. H., 2021. Invited review: The influence of immune activation on transition cow health and performance—A critical evaluation of traditional dogmas. J. Dairy Sci. 104, 8380–8410. 5.LeBlanc S. J., Lissemore K. D., Kelton D. F., Duffield T. F., Leslie K. E., 2006. Major Advances in Disease Prevention in Dairy Cattle. J. Dairy Sci. 89, 1267–1279. 6.Pineda A., Jantzi S., Dekraker K., Cartwright S., Boerefyn M., Villot C., Kvidera S. K., Steele M. A., 2024. Effects of live yeast Saccharomyces cerevisiae boulardii CNCM I-1079 supplementation during the late dry and early postpartum periods on feed intake and production responses. American Dairy Science Association Conference (ASDA). Oral Presentation. 7.Rasmussen, Philip; Barkema, Herman W.; Osei, Prince P.; Taylor, James; Shaw, Alexandra P.; Conrady, Beate et al. (2024): Global losses due to dairy cattle diseases: A comorbidity-adjusted economic analysis. In Journal of dairy science 107 (9), pp. 6945–6970. DOI: 10.3168/jds.2023-24626. About Clothilde Villot Clothilde Villot is working for Lallemand Animal Nutrition as an R&D Program Manager for silage and ruminants. With a strong background in animal science, her role is to ensure that cutting-edge research translates into tangible improvements on farms.
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