Feed & Additive Magazine Issue 47 December 2024

ISSUE FOCUS FEED & ADDITIVE MAGAZINE December 2024 59 Punicalagins have been shown to help both acute and chronic inflammation through signaling pathways associated with autophagy, a process by which the body regulates inflammatory responses. • Mango leaf is the source of a bioactive called mangiferin, which is another powerful antioxidant shown to reduce oxidative stress by protecting the mitochondria and inhibiting metabolic processes that lead to inflammation. Mangiferin also increases levels of innate cellular antioxidants such as superoxide dismutase (SOD), catalase, and glutathione. Together, these three compounds form a triumvirate that provides defense against debilitating conditions that can lead to joint dysfunction because they all can keep oxidative stress in check. Oxidative stress, or the body’s inability to neutralize free radicals and maintain balance, is at the root of causes that threaten joint health. All these ingredients are offered by Layn Natural Ingredients as part of a much broader portfolio of standardized herbs for pet and human health. As a manufacturer-direct, vertically integrated company, Layn has been servicing the health and wellness industry for over two decades. Through its use of green technology using sustainably sourced biomass, Layn continues its research in polyphenols to develop new innovations for use in pet and animal nutrition. EXPANDING JOINT HEALTH SOLUTIONS TO INCLUDE HORSES While the primary focus of joint health supplements has traditionally been on dogs and cats, horses also face significant joint health challenges that require attention. Horses, particularly those involved in sports and performance, are highly susceptible to joint degeneration and stress-related injuries due to their size, activity levels, and the repetitive impact on their joints. Joint health in horses is a critical aspect of maintaining their overall well-being, especially as they age. Horses commonly suffer from osteoarthritis and other degenerative joint diseases (DJD), particularly in their knees, hocks, and fetlocks. These conditions can significantly impair a horse's mobility, performance, and quality of life. In addition to the benefits seen in smaller animals, the polyphenol-rich ingredients in TruGro® CARE Joint Health also hold promise for supporting joint health in horses. For instance, the antioxidant properties of pomegranate and mango leaf can help reduce oxidative stress in horses, which is a key factor in preserving joint integrity. Similarly, Epimedium’s icariin plays a vital role in supporting bone density and cartilage, which is particularly beneficial for horses subjected to the high physical demands of racing, jumping, or dressage.

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