ISSUE FOCUS FEED & ADDITIVE MAGAZINE November 2024 53 the sweet taste receptors in pigs and led to the development of two new saccharin-free products: Sucram Specifeek and Sucram M’I Sweet. Additionally, Sucram N-3D is a stevia-based high-intensity sweetener with aromatic enhancers and mouthfeel stimulators that is highly appealing to calves. The inclusion of aromatic molecules provides a noticeable vanilla and caramel scent, further improving the calf’s sensorial experience. Internal research has shown that Sucram N-3D increases feed attractiveness, feed intake and body weight gain in starter calf diets. ADM’s Sucram range of high-intensity sweeteners not only activates the sweet taste receptors T1R2 and T1R3 present on the tongue, thus triggering a sweet taste, but also activates the same receptors on the surface of gut enteroendocrine cells. These receptors release the glucose-like peptide-2 (GLP-2) hormone, which leads to increased absorption of glucose from the intestinal lumen1,2. The GLP-2 hormone is notably involved in tissue reparation and increases blood flow to the gut. It fosters gut maturation and integrity and improves digestion and absorption of nutrients. SUPPORT IMMUNE RESPONSE The immune system is comprised of a complex network of cells, tissues, organs and the substances they produce. Although animals are born with certain innate defenses, the immune system continues to develop over time, adapting to diverse antigenic exposure. Efficient immune responses can greatly limit potential invaders; however, young animals with relatively immature immune systems are more vulnerable to pathogenic challenges. Maternal antibodies are transferred through the placenta and colostrum to help ward off threats in young mammals until their own immune systems are stronger. Yeasts have been fed to animals for over 100 years due to their nutritional richness and also for their reported effects to support health and growth performance. Yeast cell walls contain various bioactive components such as b-glucans and mannan oligosaccharides, which have been demonstrated to have beneficial impacts across various species3,4. Several studies have shown that dietary b-glucans interact with intestinal cells effecting modulation of the intestinal immune response4-6. Mannan oligosaccharides have been demonstrated to bind and limit the colonization of intestinal pathogens with beneficial consequences related to gastrointestinal health and ensuing performance3. Pichia guilliermondii is a novel yeast with unique morphology, structure and consequent activity. Pichia guilliermondii supplementation during sow gestation and lactation has been demonstrated to have a beneficial impact on piglet improved resilience, health and growth to market weight7-14. Furthermore, a commercial farm trial has shown dairy calves supplemented with Pichia guilliermondii and challenged with coccidiosis had reduced oocyst shedding and fewer intestinal lesions15. During a coccidiosis challenge, damage to the intestinal wall impairs nutrient absorption, thus affecting feed conversion ratio (FCR) and growth performance. Field trials have shown Oilis LD, a bioactive additive incorporated in whole milk or milk replacers for young ruminants, could increase average daily gain and improve FCR. Oilis is made of specific phytogenic compounds shown to help protect the intestinal epithelium and reinforce the calf’s natural defenses. OPTIMIZE PERFORMANCE WITH BIOAVAILABLE NUTRIENTS Trace minerals are essential nutrients supporting a variety of metabolic processes across species, including growth, fertility and immunity. However, supplementation with inorganic mineral sources may be inefficient, due to mineral antagonisms, competition for absorption and interaction with feed components. Organically bound mineral sources can bypass many of these challenges and improve bioavailability for better nutrient absorption and retention. B-Traxim 2C is ADM’s range of organic trace minerals bound to glycine (also called glycinates), designed to deliver highly bioavailable and homogenous
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