INTERVIEW FEED & ADDITIVE MAGAZINE October 2024 69 ication programs, and extreme weather contribute to increased oxidation. These conditions amplify oxidative stress and the production of oxidants. To prevent harm, oxidants must be detoxified by antioxidants. If not managed, high concentrations or prolonged periods of oxidative stress can cause significant damage to the animal and a decrease in performance and product quality. At Cargill’s Micronutrition and Health Solutions (MHS), we have had great success mitigating this stress with our cost-efficient Proviox™ 50 solution. What is Proviox™ 50, and how does it improve oxidative status and support animal performance during periods of increased stress? To combat oxidative stress, antioxidants that neutralize ROS are essential. These antioxidants naturally occur in various components at different levels. We’ve developed Proviox™ 50 as a specific blend of plant-derived polyphenols with high antioxidant activity. This blend is specially selected for its components’ ability to work synergistically, enhancing the overall antioxidant effect. Proviox™ 50 neutralizes reactive oxidant species, improving oxidative status and supporting animal performance during stressful periods. By incorporating this blend into their feed formulations, animal farmers can effectively manage oxidative stress, supporting better health and performance for their animals. Results from 100+ in-vivo trials across different species - swine, poultry, ruminant, and aqua - have demonstrated that Proviox™ 50 can help: • Improve oxidative status and support performance during periods of stress. • Reduce feed cost by reducing the level of vitamin E required in the diet. • Support reproductive performance • Support immunity Proviox™ 50 supports animals throughout the whole lifecycle, especially during challenging production phases. It is safe, stable, and suitable for multiple species. How does Proviox™ 50 help reduce feed costs by reducing the required levels of vitamin E in the diet? Firstly, it is important to highlight the role of vitamin E in the feed formulation. Vitamin E acts as a free radical scavenger – in other words, it mitigates the negative impact of oxidation caused by stress. It is a vital part of many animal diets, and any supply disruptions can have a damaging effect on the industry. In terms of feed costs, a vitamin E supply disruption can – like we have seen recently – lead to skyrocketing prices. Because vitamin E is so important to managing the balance of oxidants and antioxidants in the body, farmers must either accept the high vitamin E prices or look to innovation to mitigate the rising costs.
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