ISSUE FOCUS FEED & ADDITIVE MAGAZINE October 2024 65 Milk production increased from 1 to 8 litres/cow/day, with an average increase of 13.5% in a shorter interval (181 versus 195 days pre-nu.biom BOS). In a laboratory study using 12 Friesian dairy cows, animals fed nu.biom BOS (8 and15 g/cow/day, pre calving and calving, respectively) for 105 days had significantly increased milk production, kg fat/day and kg protein/ day (P<0.05) versus controls (Vicente et al., 2024). SUMMARY Modern dairy production is facing a series of unprecedented challenges and the scenario is unlikely to change anytime soon. Producers need to rely on a toolbox of approaches to help them maximize efficiencies and economic returns. Postbiotics are an emerging technology that offers a stable, quick and focused solution to help manage intestinal health in ruminants, improve performance and health and contribute to reducing their environmental footprint. nu.biom BOS is at the forefront of this technology, using proprietary strains and production techniques to develop species-specific and production-specific postbiotics to address the needs for the modern dairy farmer. References 1. Aditya A., Rahaman S. O. & Biswas, D. (2022) Impact of Lactobacillus-originated metabolites on enterohemorrhagic E. coli in rumen fluid. FEMS Microbiol Ecol, 98(12). 2. Fernandez, E. M., Valenti, V., Rockel, C., Hermann, C., Pot, B., Boneca, I. G. & Grangette, C. (2011) Anti-inflammatory capacity of selected Lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide. Gut, 60(8), 1050-1059. 3. Fernández, C., Romero, T., Badiola, I., Díaz-Cano, J., Sanzol, G. & Loor, J. J. (2023) Postbiotic yeast fermentation product supplementation to lactating goats increases the efficiency of milk production by enhancing fiber digestibility and ruminal propionate, and reduces energy losses in methane. J Anim Sci, 101, skac370. 4. Golowczyc, M. A., Mobili, P., Garrote, G. L., Abraham, A. G. & De Antoni, G. L. (2007) Protective action of Lactobacillus kefir carrying S-layer protein against Salmonella enterica serovar Enteritidis. Int J Food Microbiol, 118, 264-273. 5. Guo, J., Zhang, Z., Guan, L.L. Yoon, I., Khafipour, E. & Plaizier, J.C. (2024) Postbiotics from Saccharomyces cerevisiae fermentation stabilize rumen solids microbiota and promote microbial network interactions and diversity of hub taxa during grainbased subacute ruminal acidosis (SARA) challenges in lactating dairy cows. Front Microbiol, 15:1409659. 6. Izuddin, W. I., Loh, T. C., Foo, H. L., Samsudin, A. A. & Humam, A. M. (2019) Postbiotic L. plantarum RG14 improves ruminal epithelium growth, immune status and upregulates the intestinal barrier function in post-weaning lambs. Sci Rep, 9, 9938 7. Mathur, H., Linehan, K., Flynn, J., Byrne, N., Dillon, P., Conneely, M., Grimaud, G., Hill, C., Stanton, C. & Ross, R.P. (2022) Emulsion-based postbiotic formulation is comparable to viable cells in eliciting a localized immune response in dairy cows with chronic mastitis. Frontiers in Microbiology, 13, p.759649. 8. Swanson, K. S, Gibson, G. R, Hutkins, R., Reimer, R. A, Reid, G., Verbeke, K., Scott, K. P, Holscher, H. D., Azad, M. B., Delzenne, N. M. & Sanders, M. E. (2020) The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics. Nat Rev Gastroenterol Hepatol. 17(11):687-701. 9. Vicente, F., Campo-Celada, M., Menéndez-Miranda, M., García-Rodríguez, J. & Martínez-Fernández, A. (2024) Effect of postbiotic supplementation on nutrient digestibility and milk yield during the transition period in dairy cows. Animals, 14, 2359. About Dr. David Harrington Dr. David Harrington is the Director of Product Management for nu.ance Biotechnology (Switzerland). He has over 25 years working in the animal health industry in the development and commercialisation of biologicals and feed additives for livestock.
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