Feed & Additive Magazine Issue 42 July 2024

July 2024 Year: 4 Issue: 42 Feed Additive INTERNATIONAL MAGAZINE FOR ANIMAL FEED & ADDITIVES INDUSTRY Mark van Nieuwland, dsm-firmenich Saving 1 ton of CO2e per cow per year with Bovaer® Liz Homer, Trouw Nutrition A holistic approach to sustainability from calf to 5th lactation Vivek Kuttappan, Cargill Innovative approach to develop effective feed ingredients www.feedandadditive.com Environmental Footprint of Livestock and Feed Industry Feed Yeast and Global Market Status

The livestock and animal feed industry plays a vital role in our global food security and nutrition. However, its significant environmental impacts such as greenhouse gas emissions, land use, water pollution and biodiversity loss cannot be ignored. In this month's issue, we will look at the environmental footprint of the livestock and feed industry and explore some of the efforts being made to ensure the sustainability of this critical industry and reduce its environmental impact. In recent years, important steps have been taken to reduce the carbon footprint of the livestock sector. Researchers are developing innovative solutions such as feed additives and new nutritional diets to reduce methane emissions. In particular, efforts are focused on reducing methane emissions from cows. The latest solutions in this area include algae-based feed additives, special probiotics, nutritional diet changes, genetic selection, etc. Internationally, legislative regulations to reduce the environmental impact of livestock farming activities and the animal feed industry is on the rise. Some regions, such as the European Union, have set targets to limit greenhouse gas emissions and promote sustainable agricultural practices. These regulations encourage the sector to move towards more environmentally friendly methods and direct investments. However, it is also important to protect farmers and producers while reducing environmental impact. Shifting to sustainable practices can cause additional costs and technical challenges. It is therefore essential to create a transformation plan that moves forward in a fair and inclusive way, with the participation of all stakeholders in the sector. In conclusion, the livestock and animal feed industry play a critical role in the transition to a sustainable future. Through innovative solutions, international regulations and collaboration with industry stakeholders, it is possible to support food security and nutrition while reducing the environmental impact of the sector. This joint effort will ensure a healthier planet and a safer food system for future generations. Hope to meet you in our next issue... Enjoy your reading! Publisher Muhammed Akatay [email protected] Responsible Manager Özlem Akatay [email protected] Editor-in-Chief Derya Yıldız [email protected] Editors Bahadır Büyükkılıç Burak Varol Zeynep Demirkaya [email protected] Communication & Marketing Lisa Atakul [email protected] Design Alper Kandemir [email protected] Web Design Caner Cem Pulat [email protected] Circulation and Data Responsible Amine Şengün [email protected] Ataturk St. Metropol Istanbul Ste. Block C1, No:376 Atasehir, Istanbul/TURKEY Phone: +90 850 220 5064 E-Mail: [email protected] Web: www.feedandadditive.com Publication Type: Periodic (Monthly) EDITOR Growth while Reducing Environmental Impact Derya YILDIZ © Three Plus Media | All rights reserved. Reproduction, in whole or in part, is prohibited without the written permission of the publisher. *DISCLAIMER: All views and ideas expressed in articles published in the magazine reflect the point of views of the author(s), not that of the Editor-in-Chief, Editors, Editorial Board or Publisher of Feed & Additive Magazine. The Editor-in-Chief, Editors, Editorial Board and Publisher assume no responsibility or liability in such cases. The publisher does not give any warranty and representation to the accuracy or completeness of the contents and data published in the magazine. All responsibility of the contents, articles and information published in the magazine belongs to the authors. The publisher and the authors cannot be held responsible for any damages resulting from the use of the whole or part of the content of the magazine. feedandadditive

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CON T E N T S 28 THE ROLE OF ENVIRONMENTAL ASSESSMENT IN DRIVING EFFICIENCY, PROFITABILITY AND SUSTAINABILITY Ben Braou, Alltech E-CO2 43 UNLOCKING RUMINANT POTENTIAL WITH VOLAC Sarah Banks, Volac International Ltd 52 NEXT GENERATION LOME: AN ADDITIVE FOR THE MASSES Cora Taylor, Volta Greentech 54 RECYCLABLE PLASTIC AND LESS TRANSPORTATION REDUCE CLIMATE FOOTPRINT OF COD PRODUCTS By Nofima 32 FROM CHINA TO CORNELL: PROPELLING INNOVATION IN METHANE EMISSION REDUCTION Joanne Sharpe, Cargill 46 REDUCING AMMONIA IN POULTRY PRODUCTION WITH CRISPR-CAS Robert Habgood, Folium Science 35 POULTRY UNDER PRESSURE: UNDERSTANDING & COMBATING THERMAL STRESS Etienne Effenberger & Dr. Melinda Culver, Biochem 49 HARNESSING SEAWEED'S POWER TO SLASH LIVESTOCK METHANE EMISSIONS AT SCALE Steve Meller, PhD, CH4 Global 40 SAVING 1 TON OF CO2E PER COW PER YEAR WITH BOVAER® Mark van Nieuwland, dsm-firmenich 26 ISSUE FOCUS ENVIRONMENTAL FOOTPRINT OF LIVESTOCK AND FEED INDUSTRY 56 A HOLISTIC APPROACH TO SUSTAINABILITY FROM CALF TO 5TH LACTATION Liz Homer, Trouw Nutrition 60 PET FOOD INDUSTRY'S ROLE IN SUSTAINABILITY Jim Lamancusa, Pet Sustainability Coalition SUSTAINABILITY

CON T E N T S 63 ENHANCING FEED PALATABILITY WITH SENSORY ADDITIVES Anne Manubens, Herbarom Laboratoire 70 INNOVATIVE APPROACH TO DEVELOP EFFECTIVE FEED INGREDIENTS Vivek Kuttappan, Cargill Animal Nutrition & Health 74 INSIDE A YEAST PLANT: PRODUCING QUALITY LIVE YEAST FOR ANIMAL NUTRITION Jean François Hupé & Catherine Desautels, Lallemand Animal Nutrition 78 NOVEL IMMUNOMODULATORS IN AQUACULTURE Pathinathan Philominal, Andhra Pradesh Fisheries University ARTICLES EU feed industry discusses feed autonomy and circularity 16 CH4 and CirPro: Methane-reducing feed additive increases feed efficiency 90 Adisseo to allocate €1 million to support research in feed industry 10 CPM opens its new state-of-the-art facility 15 Nutreco celebrates launch of its Garden of the Future 13 Anitox joins Iluma Alliance 18 Kemin unveils cloud-based technology for rendering operations 97 NEWS FRENCH FEED ADDITIVE COMPANY NUQO EXPANDS WITH NEW AFFILIATES Ewenn Helary, Nuqo INTERVIEW MARKET REPORT FEED YEAST AND GLOBAL MARKET STATUS 80 66

6 FEED & ADDITIVE MAGAZINE July 2024 Close to ten years ago, every country in the world came together to develop a shared ‘blueprint to achieve a better and more sustainable future for all.’ The outcome was 17 Sustainable Development Goals (SDGs) that would guide global efforts to build a society that can deliver continued progress for generations to come. Since then, the world has dramatically accelerated efforts to strengthen sustainability across industries. For the livestock sector, this offered an opportunity to showcase existing efforts and invest in new strategies for the future. Livestock health was always recognized by producers as an important sustainability pathway, improving efficiency and reducing productivity losses. For instance, the global beef sector has made it a pillar of their 2030 sustainability goals. However, animal health has been continually overlooked by policymakers when developing national strategies. The result is 20% of livestock production is still lost to disease each year, costing producers $300 billion and emitting higher emissions than needed. However, this is beginning to change. In 2022, the United Nations Food and Agriculture Organisation (FAO) urged nations to integrate animal health into their national climate commitments, calling it “vital for sustainable livestock production.” Last year, the UN further emphasized animal health when it released its global roadmap for ‘Achieving SDG 2 without breaching the 1.5 °C threshold.” The Roadmap recognized the importance of livestock to 1.7 billion farmers worldwide, and offered proven pathways for addressing its climate footprint including better genetics, feed, and animal health. In fact, an accompanying UN report calculated the effects of different steps to address livestock emission, finding that: - Productivity increases would reduce emissions 20% - Feed improvements by 12% - Better animal health by 10% - Improved genetics by 8% - Methane reducing feed additives by 5% This 50%+ combined reduction is in comparison to actions like diet changes in people, which the report found only reduced emissions by 4%. This growing recognition of the value of animal health and related technologies has the potential to dramatically improve livestock sustainability and decrease its carbon footprint. This will require increased use of veterinary vaccines, strong biosecurity protocols, improved feed and use of additives, better breeding practices and adoption of new digital technologies. Each area offers opportunities to cut emissions while also increasing productivity. VACCINES Disease prevention is the cornerstone of livestock health and sustainable production. When animals are healthy, they produce more with less feed, water and other resources, which means farmers can meet consumer needs with fewer animals at a lower climate footprint. Researchers have found that when disease strikes, it can increase emissions in beef cattle up to 113% and by 24% in dairy. Vaccination avoids this dramatic impact by stopping disease before it strikes. THE ROLE OF ANIMAL HEALTH IN SUPPORTING LIVESTOCK SUSTAINABILITY AND HELPING MEET CLIMATE GOALS Carel du Marchie Sarvaas Executive Director HealthforAnimals LEAD ARTICLE

FEED & ADDITIVE MAGAZINE July 2024 7 However, too many barriers still exist to vaccine uptake, ranging from lack of investment to cold chain infrastructure to slow regulatory approvals. Policymakers must come together in the coming years to work with vaccines manufacturers to develop new strategies for getting vaccines to more farmers and veterinarians in a faster, more effective manner. BIOSECURITY While vaccines are an essential tool, they are not available for all diseases and not every illness can be avoided. Biosecurity offers a complementary method for preventing disease through practices that keep disease off the farm altogether. These can be simple steps like boot sanitization stations, to more complex systems like indoor animal rearing and quarantines. This spectrum of biosecurity tools means there are opportunities for better prevention on farms of every size, sophistication, and system. A recent study found that prevention of highly pathogenic avian influenza (HPAI), which many countries achieve through biosecurity, reduces poultry emissions by approximately 11%. IMPROVED FEED AND NUTRITION The past decade has seen substantial improvements in understanding of the gut microbiome of animals and how it supports disease prevention. This has helped animal health companies develop a range of nutritional supplements that improve gut health, leading to lower levels of diseases like necrotic enteritis that sap productivity and increase the environmental footprint of production. Furthermore, an emerging area of feed additives like 3-NOP can reduce the amount of methane produced in the gut of a cattle, which U.S. Department of Agriculture funded research found led to a 25% reduction in cattle methane emissions. BETTER BREEDING Just like in people, an animal’s genetics can dictate whether it will be vulnerable to various health ailments. Breeding is therefore a critical component of any health strategy to help ensure that the animals that arrive on the farm have an innate resistance to certain diseases and can produce more efficiently in that region. Studies in Europe have shown that better genetics could reduce livestock emissions in the European Union by 8%, while in the Netherlands a focus on genetics could slash methane emissions by 24%. DIAGNOSTICS AND DIGITAL Increasingly sophisticated farms are shifting from not just preventing disease but predicting it and taking action before it has an opportunity to strike. For instance, widespread use of diagnostics across farms allows researchers to track the movement of disease across borders and support farms in taking preventative measures before it arrives on their doorstep. On the farm itself, new digital tools like smart sensors alongside 24/7 video and sound monitoring mean A.I.-driven tools can detect the very first cough or elevated temperature of a sick animal before a person can. Farms can then isolate sick animals and prevent the spread of disease that could wipe out a herd. ANIMAL HEALTH AND THE FUTURE AHEAD Animal health tools to strengthen, prevent disease, improve sustainability and reduce emissions in livestock are available. Global institutions are increasingly recognizing them as a key pathway in addressing both hunger and climate simultaneously. The next step is for governments to take the necessary local actions to ensure farmers, veterinarians and other animal keepers can access these technologies and have the necessary support to use them. This means: - Ensuring proper access to veterinary expertise to help with deployment; - Building regulatory systems that allow safe, effective animal health products to quickly reach those in-need; - Providing the appropriate support to help farms adopt animal health products that provide significant societal benefits; - Working directly with animal health companies to set long-term strategies that can help new vaccines and other products reach the market, particularly in outbreak scenarios. These actions will ensure that when world leaders measure global progress against the SDGs in 2030, animal health will have been one of the drivers of livestock’s contributions.

NEWS 8 FEED & ADDITIVE MAGAZINE July 2024 dsm-firmenich, innovators in nutrition, health and beauty, announced an agreement to sell its yeast extract business to Lesaffre, a key global player in fermentation and micro-organisms. Yeast extracts is part of dsm-firmenich's taste, texture & health business unit, with annual sales of about €120 million. As part of dsm-firmenich's tuning of its portfolio, the company de-prioritized certain business segments. The divestment from yeast extracts is an outcome of that strategic review process, which was announced on June 3. As part of the transaction, Lesaffre will enter into an agreement to supply yeast extracts to dsm-firmenich for its Savory business. In addition, dsm-firmenich and Lesaffre will enter a technology partnership for the development of yeast extracts. After the completion of the deal, dsm-firmenich will continue to supply yeast extracts produced in Delft to Lesaffre until the end of 2025, after which point the yeast extracts production in Delft will be discontinued. Lesaffre will ensure uninterrupted supply to yeast extracts customers and provide them with the same service levels and innovation support as today. Also, as part of the deal, some of the dsm-firmenich employees working on yeast extracts will transfer to Lesaffre. Read more>> Purdue University will partner with Elanco Animal Health and become part of Indiana’s new One Health Innovation District. The announcement was made at Indiana’s 2024 Global Economic Summit after Purdue President Mung Chiang and Elanco President and CEO Jeff Simmons signed a shared Memorandum of Understanding with the Indiana Economic Development Corp. to establish a globally recognized research innovation district dedicated to optimizing the health of people, animals, plants and the planet. Purdue and Elanco have committed to develop a new shared-use facility on 3 acres in the One Health Innovation District near the future Elanco global headquarters on the western edge of the White River in Indianapolis, US. The facility is designed to deliver and scale up innovation where industry and academia can collaborate including office, wet lab and incubator space. This is in addition to the nearly complete 220,000-square-foot corporate headquarters of Elanco Animal Health, with an expected opening date in the second quarter of 2025. Elanco also announced its commitment to purchase an additional 12 acres to the north of its existing footprint for future expansion and the development of the Epicenter for Animal Health. “Totality of Purdue to the totality of Indianapolis — that’s our pledge as the Indianapolis part of Purdue’s main campus officially launches on July 1,” said Chiang, Purdue President. “In the coming years, all programs at Purdue will find homes throughout our state’s capital city. Today’s announcement carries a special excitement for the partnership and the location. Purdue is excited to partner with Elanco and other collaborators to build out the ecosystem of One Health Innovation District, starting from the building announced and expanding to an entire district. Human health, animal health, plant health will be jointly advanced by the nation’s leading companies and our state’s top-ranked university.” Read more>> dsm-firmenich sells its yeast extract business to Lesaffre Purdue and Elanco partner for new innovation district

NEWS FEED & ADDITIVE MAGAZINE July 2024 9 Adisseo, one of the global leaders in animal nutrition and health, launched Secure Performance program. According to the company's statement, this innovative initiative addresses the resilience of poultry and swine in fluctuating and challenging contexts. In modern poultry farming, bacterial infections pose a significant threat to flock health. Adisseo emphasizes that it is commitment to addressing this challenge by developing effective prevention strategies to manage bacterial pressure and improve overall flock health. Similarly, swine farming faces persistent challenges such as temperature fluctuations, high-density environments, and emerging pathogens, which worsens the negative impact of bacteria. Additionally, the restrictions on antibiotic use further complicate pathogen management strategies at farm level. One approach to securing performance in challenging conditions is enhancing animal resilience. Adisseo reveals that it leverages its scientific and technical expertise to support poultry and swine customers in building resilience to thrive through challenges. By implementing tailored feed supplements strategies that ensure safer feed, and bolster gut health and immunity, the company works to significantly reduce the incidence and severity of bacterial infections in poultry populations. Julie Duong, Poultry Customer Solution Manager at Adisseo, emphasizes that: “Our Secure Performance program is dedicated to promoting efficient and responsible poultry farming through antibiotic reduction practices. By enhancing poultry resilience against bacterial pressure, Adisseo aims to ensure the health and productivity of poultry populations.” Read more>> Adisseo reveals its program for animal resilience Kemin Industries, a global ingredient manufacturer, announced the launch of CholiGEM™, an advanced rumen-protected choline supplement designed to address fatty liver and ketosis in lactating dairy cows, into the U.S. dairy market. Choline—one of the foundational ingredients of CholiGEM—is an essential nutrient for dairy cows with multiple functions for optimal milk production, reproduction, and health, especially during the critical transition period. It improves metabolic functions of the liver and increases milk fat yield and milk protein, Kemin explains. "Research shows that 50 – 60% of post-calving cows experience moderate to severe fatty liver," said Fei Sun, Ph.D., P.A.S., Dairy Marketing Manager, Kemin Animal Nutrition and Health – North America. "But if we can optimize liver health during the transition phase, we can significantly reduce metabolic disorders that compromise not only production, but overall animal health. That's where choline chloride, the key ingredient of CholiGEM, can help." According to a statement from Kemin, CholiGEM stands out with a typical 60% choline chloride content—significantly higher than the typical 28% currently available on the market. This higher content ensures a more flexible diet formulation during the critical transition period. Its superior bioavailability supports reducing fatty liver risks and ketosis occurrences, thereby enhancing overall dairy cow well-being pre- and post-calving. Read more>> Kemin introduces choline supplement for dairy cows in US

NEWS 10 FEED & ADDITIVE MAGAZINE July 2024 Adisseo, one of the global leaders in animal nutrition and health, announced the launch of the third edition of its International Research Grant, continuing its commitment to advancing collaborative research in the feed industry. Building on the success of the previous edition, this grant will allocate €1 million over the next three years to fund research projects addressing key challenges in animal nutrition. Through this initiative, Adisseo aims to foster international collaboration among leading laboratories and drive innovation in the industry. The selection process for this Adisseo Research Grant will be overseen by a prestigious Scientific Committee, with academic professors: Prof. Richard Ducatelle, Veterinary Pathology, Ghent University (Belgium), Prof. Yuming Guo, Animal Science and Technology, China Agricultural University, Beijing (China), Prof. Mike Kidd, Center of Excellence for Poultry Science, University of Arkansas (USA), Prof Defa LI, Professor, China Agricultural University, Beijing (China), Prof. Bruno Silva, Professor, UFMG Universidade Federal de Minas Gerais (Brazil), Dr. Japp Van Milgen, Senior Scientist, INRAe (France); and feed industry representatives: Dr. Jaume Coma, Corporate Director for Vall Companys (Spain), Dr. Carlos Kippert, Technical Advisor in Swine for BRF (Brazil), Dr. Marco Penz, Key Account Dir for Cargill (Brazil), Dr. Ferry Poernama, R&D Director for JAPFA (Indonesia), Dr. Pairat Srichana, R&D Director for CP (Thailand), Dr. Tom Weber, Technical Manager for Kent Nutrition Group (USA). Read more>> Novus International, Inc., an intelligent nutrition company providing solutions for the global animal agriculture industry, recently moved its global headquarters in Missouri, US. The company has explained that it is focusing on research, new product development, and innovation in its new global headquarters. “America’s heartland has been home to our global headquarters since our founding in 1991. It was important for us to stay in Missouri and remain centrally located to our customers throughout the U.S.,” says Dan Meagher, Novus President and CEO. “While the new building is perfect for today’s Novus, the improvements we’ve made in the new lab at HQ are helping us plan for the animal agriculture industry of tomorrow.” Located at 17988 Edison Ave., in a suburb of St. Louis, the already existing building was redesigned with the future in mind. “The new space is more focused on R&D and efficiency to help further our commitment to innovation,” adds Paula Fisher, Manager of Analytical Services and R&D at Novus. “It’s a space that truly provides us the opportunity to develop and formulate intelligent, next-generation solutions to support the ever-changing landscape of our customers in the animal agriculture industry.” Read more>> Adisseo to allocate €1 million to support research in feed industry Novus moves its new global headquarters

NEWS FEED & ADDITIVE MAGAZINE July 2024 11 Adisseo, Your Partner in Problem-Solving, By focusing on enhancing animal resilience and offering comprehensive and tailored solutions to combat stressors, Adisseo aims to be your trusted partner in addressing the challenges of modern animal farming. Resilience: Thriving through Challenges SECURE PERFORMANCE www.adisseo.com Ensure feed safety and quality Cope with the environmental challenges Optimize gut’s functions

NEWS 12 FEED & ADDITIVE MAGAZINE July 2024 Hungarian insect producer Agroloop agreed with Germany-based WEDA Dammann & Westerkamp on the feeding technologies of its new black soldier fly larva (BSFL) rearing facility to be established for animal feed. The plant for the industrial production of the feed insect is currently being built near Budapest Airport, and will go into operation in Autumn 2024. Agroloop Hungary is significantly increasing its existing larvae breeding capacities for the European market with the plant investment of more than 20 million euros. By the end of this year, the agrotech company is expected to receive 120 tonnes of raw material per day, of which 6,000 tonnes of soil improver granules, nearly 3,000 tonnes of feed protein and more than 600 tonnes of feed fat will be produced annually – producing around 10,000 tons of end product in its 13,000 square metre plant. High-quality insect-based feed proteins are increasingly being used as a health-promoting source of protein for the pet food and livestock feed segment. In view of a rapidly growing world population, the global demand for animal proteins is expected to increase by around 100% by 2050. It is estimated that the insect feed market will reach a total annual turnover of €2 billion by the end of the decade, producing 1 million tonnes of insect meal per year. Read more>> Agroloop builds BSFL factory for animal feed NAIC to serve as innovation hub for insect protein industry NRGene Canada, NRGene's Canadian subsidiary, announced the opening of the North American Insect Center (NAIC). This research center for collaborative innovation was established together with the Swiss technology group Bühler marking a significant milestone in the advancement of insect protein production in North America. The North American Insect Center (NAIC) is located at NRGene Canada's facility in Saskatchewan. This cutting-edge center will serve as a testing and demonstration facility for both companies' customers, offering them the opportunity to evaluate the performance of chosen Black Soldier Fly (BSF) varieties on the by-product streams available to the customers. The NAIC will allow customers to assess BSF varieties, operational parameters, and practices for efficient industrial-scale production. NRGene Canadian emphasizes that this collaborative approach enables informed decisions and maximizes BSF's potential as a sustainable protein source. The center will serve as a hub for innovation, supporting the growth of the insect protein industry in North America. Additionally, the center will offer workshops, training sessions, and seminars to educate the industry stakeholders on the benefits and best practices of insect protein production. Read more>>

NEWS FEED & ADDITIVE MAGAZINE July 2024 13 Nutreco celebrated the opening of its Garden of the Future, the new hub for its Phytotechnology program. Located in Thurgau, Switzerland, the groundbreaking facility gathers all of Nutreco’s phytotechnology activities, from discovery and experimental cultivation to plant development and production, under one roof. The two-day grand opening event showcased the work being done at the Garden of the Future for customers and journalists through garden tours, presentations and workshops by members of the company’s exploration team. Nutreco’s new CEO David Blakemore offered opening and closing remarks and its Chief Science Officer David Bravo was the keynote speaker on both days. The Garden of the Future facility includes access to a 500 square meter experimental greenhouse for plant breeding and propagation, a 5,000 square meter vegetative mass propagation greenhouse, around 30 hectares of cultivation space and a “Future Garden” to display the facility’s novel plants. Nutreco’s Garden of the Future is led by its Director Dr. Bernd Büter, who is also Director of the company’s Phytotechnology Program. Dr. Karin Berger, Phytotechnology Discovery Director, serves as ethnobotanist, responsible for screening the plants and confirming their efficacy. Read more>> Nutreco celebrates launch of its Garden of the Future Supplant D Health and performance go hand in hand • Improved health status • Stable rumen environment • Smoother transition • Reduced somatic cell count agrimprove.com Aromabiotic® Cattle

NEWS 14 FEED & ADDITIVE MAGAZINE July 2024 Nofima, a leading food research institute that conducts research and development for the aquaculture industry, the fishing industry and the food industry, examined consumers' beliefs and thoughts regarding salmon. Katerina Kousoulaki, a senior scientist at Nofima, is currently leading a project aimed at creating sustainable salmon feed from algae and insect meal. In the future, the salmon industry will require a greater diversity in sustainable raw materials which are beneficial to both salmon and the environment than current options, and microalgae and insects are promising raw materials. This is why Kousoulaki has been listening in on focus groups where French consumers of salmon have discussed their beliefs and thoughts. “The respondents loved eating salmon, but did not know much about the fish,” says Kousoulaki. “My impression is that we need to educate the consumers.” It turns out that consumers know very little about Norwegian salmon. What's more, they think they “know” several things that are in fact wrong. “Everyone was sure that farmed salmon contains lots of antibiotics – which is not correct. They like to eat salmon, but they don’t know much about how it is produced,” she states. According to Kousoulaki, when the existing knowledge is lacking, it makes it even more challenging to talk about feed with new raw materials. “If you ask people what salmon eat in the wild, many will answer ‘algae’ and ‘shrimp’. However, salmon don’t eat algae, and they don’t eat much shrimp, either. They mainly feed on fish, and upriver they feed on insects,” Katerina Kousoulaki explains. “Many of the surveyed consumers had a positive attitude towards using algae in fish feed, but did not think that insects were a natural food for the salmon.” Read more>> Kemin Industries launched FORMYL™, an innovative feed additive designed to enhance swine health and productivity, in the United States. The cutting-edge solution from the Kemin Animal Nutrition and Health – North America business unit reportedly uses a proprietary blend of encapsulated calcium formate and citric acid, ensuring optimal delivery and efficacy. According to the statement from Kemin, FORMYL offers numerous benefits and features, including: • Effective feed acidifier to address pathogens and promote a healthy gut environment • Non-antibiotic solution of formic acid contributes to minimizing the presence of Enterobacteriaceae challenges and Escherichia coli • Encapsulation technology that ensures safer handling and maximum impact in the animal Calcium formate was recently approved in the U.S. for use as a feed acidifying agent in complete swine and poultry feeds. Research has shown calcium formate is a highly effective feed acidifier and antimicrobial agent that can combat pathogens by damaging their cell membranes. Read more>> Nofima: Consumers distrust use of insects and microalgae in salmon feed Kemin introduces new feed acidifier for swine health in US

NEWS FEED & ADDITIVE MAGAZINE July 2024 15 Superior & Sustainable Animal Feed Solutions We build equipment that just runs. CPM is the world’s leading provider of innovative and automated solutions for new equipment and aftermarket. CPM Holdings Inc., one of the leading global suppliers of process equipment, engineered technologies and related aftermarket parts and services, unveiled its new state-of-the-art facility to serve the animal feed, oilseed, alternative fuel and other industries. The new site in Waterloo, Iowa, US, produces a wide variety of equipment including pellet mills, flaking mills, hammermills, roller mills, pellet crumblers and related aftermarket parts. The 172,960-squarefoot building includes space for advanced manufacturing, modern workspaces and offices, testing and application development, and equipment and parts engineering and design. The facility houses 177 employees and led to the creation of 20 new jobs. The facility’s new state-of-the-art testing lab features a larger space for maneuverability and ease of use, upgraded ‘clean lab’ with private customer room, and wall-to-wall windows for full viewing of the testing area from the clean lab office area. “CPM is committed to continuing our legacy of leadership from our new state of the art facility in Waterloo,” said David Webster, Chief Executive Officer (CEO) of CPM. “We’re proud of this impressive new facility which will enable us to maintain our product leadership through development of new products and bringing new innovations into our markets. Our commitment is to provide the best solutions and service for our customers. Our new facility will be a key piece in executing on our mission to feed, fuel, and build a better world.” Read more>> CPM opens its new state-of-the-art facility

NEWS 16 FEED & ADDITIVE MAGAZINE July 2024 Research conducted by Selko, the feed additives brand of Nutreco, shows how the source of trace minerals can support monogastric animals’ immune response in livestock production. The findings further reveal that combining more bioavailable trace mineral sources in poultry diets may improve flock performance and zootechnical variables. The findings will be presented at the European Poultry Conference (EPC), 24-28 June in Valencia, Spain. Steering immune responses under an LPS challenge: During EPC, Gavin Boerboom, Selko’s Global Program Manager for Minerals, will share findings from trials that looked at the efficacy of IntelliBond trace minerals in supporting birds under an LPS challenge compared to birds receiving inorganic sources of zinc and manganese. Boerboom will comment on findings revealing how physiological activities inside the bird, including the superoxide dismutase (SOD) response, are elicited by trace mineral source. His remarks will shed light on internal processes that drive functions linked with performance improvements including improved uniformity and resilience. “The more we discover about how nutrition influences the animal’s immune response, the more we can use the diet to address production stressors such as a disease challenge or heat stress,” Boerboom said. Selko’s research expands on previous IntelliBond trace mineral studies evaluating how trace mineral source affects critical functions that drive performance. While earlier studies have shown that feeding a less soluble, higher-quality source of zinc, manganese and copper trace mineral can help support reproduction, growth and immunity, new findings help explain the mode of action driving improved immune response and resiliency. Read more>> Selko to share how trace minerals support immune response at EPC The European Feed Manufacturers’ Federation (FEFAC) held its 68th Public Annual Meeting on 31 May 2024 in Brussels (ACE Events), attended by 121 participants. The main theme of this year's Public Annual Meeting was "How to boost EU feed autonomy and strengthen Circularity of the EU feed and& livestock sector?” in the context of the new EU Strategic Agenda 2024 – 2029. The programme featured keynote contributions from Pierre Bascou, DG AGRI Acting Deputy Director General and Patrick Pagani, Copa-Cogeca Deputy Secretary General, as well as two panel sessions focusing on the EU feed protein autonomy and reductions of carbon emissions in the livestock sector. “It is clear that the feed sector has a crucial role to play in supporting a vibrant European livestock sector that can improve its performance on elements such as reduced strategic import dependencies, reduced carbon emissions and increased circularity. FEFAC, therefore presented its 12 key recommendations for the EU Strategic Agenda 2024-2029 regarding the livestock sector to the Belgian EU Council Presidency,” said Pedro Cordero, FEFAC President. Read more>> EU feed industry discusses feed autonomy and circularity

NEWS FEED & ADDITIVE MAGAZINE July 2024 17 At Phileo, we believe in microorganisms and fermentation technologies to make a difference for a more sustainable future. By mastering microbiota and immunity, we offer our partners beneficial probiotics and functional ingredients to improve animal health and performance through nutrition. Act with nature for animal care. Life science to improve animal health and performance

NEWS 18 FEED & ADDITIVE MAGAZINE July 2024 Feed safety specialist Anitox is now part of Iluma Alliance, the global business ecosystem dedicated to creating value for the feed and food industry. Confirming the transaction, Anitox CEO Chris Tecca explains: “We are delighted to be joining Iluma Alliance, an organization which proactively contributes to a better-nourished world through investment in new technologies and evidence-based solutions." “Anitox will continue to operate independently, focusing all our attention on delivering exceptional customer value in our specialism: protecting feed mills and animal feeds from harmful bacteria and viruses to improve productivity and biosecurity. Our identity, brands including Termin-8 and Finio, teams and geographic footprint are all preserved. As a result of this move, and the innovation at the heart of Iluma Alliance, the future looks very bright indeed,” Tecca adds. Read more>> Anitox joins Iluma Alliance Thanks to the cooperation between value chain partners in the Scottish aquaculture industry, salmon sold with the prestigious ‘Label Rouge’ (Red Label) can now be fed diets containing insect-derived ingredients during the juvenile stages. Label Rouge production represents 12% (8,900T) of Scotland’s salmon exports, a significant and growing segment of the industry. It is thus the ideal breeding ground to support premium responsibly sourced ingredients. This endorsement was achieved in an initiative that brought together INAO, the French Label Rouge regulatory authority; Landcatch, the Hendrix Genetics’ genetics brand for salmon breeding; Scottish Quality Salmon which acts as the management organisation (ODG) for Scotland's salmon producers and companies; and the leading company in insect ingredients worldwide, Protix. The internationally recognised Label Rouge requires compliance with stringent standards to ensure the best quality products for consumers. This includes specifications for feed that limit the types and amounts of ingredients that farmers can use across the lifecycle of the salmon. In a recently approved update to these specifications, insects can now be included in the diets of juvenile (freshwater) salmon – marking a significant shift for the Scottish industry towards a feed and food system with a lower footprint. This important watershed comes at a time when the industry is also increasingly putting larger smolt to sea. Novel ingredients broaden the ingredients basket and are an important instrument in the sector’s toolkit as they push towards carbon neutrality by 2045. Protix points out that its insect meals have a carbon impact almost 89% lower than a similar soy alternative (soy protein concentrate) per kg, while being a closer analogue to the salmonids’ natural diets. Feed represents up to 80% of the carbon impact of the salmon sector, and innovation in this space drives demonstrable impact. Read more>> Salmon produced under Label Rouge standard to be fed insects

NEWS FEED & ADDITIVE MAGAZINE July 2024 19 Safer ingredients for safer feed. Saving feed ingredient processors millions in lost productivity dsm-firmenich, an innovator in health, nutrition, and beauty, and BESTMIX Software, one of the leaders in feed and pet food production solutions, announced their strategic partnership to measure and manage the environmental footprint of animal feed. Roughly one-third of the world’s greenhouse gas emissions come from food production. Companies along the feed and food value chain are increasingly called upon to measure, report and reduce their environmental footprints because of their own sustainability commitments, regulatory requirements and consumer preferences—requiring considerable amounts of data. The partnership links BESTMIX® Software's feed formulation with the Sustell™ full life cycle assessment (LCA) platform, allowing customers to generate and share their feed footprints easily. With this solution, feed producers, who play a major role in enabling sustainable animal protein, can report the environmental impact of their feed with the click of a button, leveraging existing data in their trusted BESTMIX software suite. This integration assists feed producers in addressing future demands of feed labelling, while simultaneously helping farmers accurately quantify the environmental impact of products such as eggs, meat, milk, and farmed seafood. Read more>> dsm-firmenich and BESTMIX Software team up for sustainable feed production

NEWS 20 FEED & ADDITIVE MAGAZINE July 2024 Eurofins Agro Testing Wageningen, a laboratory specializing in forage, feed, soil, water, manure and compost analysis, announced an international collaboration with trinamiX, a developer of cutting-edge biometric and mobile NIR spectroscopy solutions. The collaboration aims to optimize forage analyses without the need to send samples to a laboratory. The partnership brings together Eurofins Agro Testing’s expertise in state-of-the-art analysis, its global network of laboratories and extensive knowledge of the agri-food industry with trinamiX’s technology to offer on-the-spot analytics in a fraction of the time it takes for a traditional sample to be analysed. Hans Martin, Managing Director Eurofins Agro Testing Wageningen, emphasizes that its customers rely on best-in-class laboratory services to run their businesses profitably and sustainably. Combining this analytical data with trinamiX’s technology is the best way for the industry to improve livestock health and productivity. According to the companies, the collaboration is set to revolutionise the way feed suppliers, nutritionists, and farmers capture feed data to enable more accurate nutrition management. Bringing trinamiX’s technology and Eurofins Agro Testing’s analysis together in this partnership is set to provide high quality analysis with the flexibility to provide data and insight anywhere in the world. Read more>> Eurofins and trinamiX join forces for feed efficiency A University of New England controlled cattle study found the methane yield was slashed by 81 per cent when trial cattle had access to water troughs dosed with Rumin8’s methane reducing livestock supplements, indicating a new tool is emerging to help cattle farmers who rely on grazing production systems to lower their methane emissions. Delivery of Rumin8’s water-based formulation to cattle through water troughs opens up opportunities to reduce methane emissions from cattle in either remote, rangeland operations, or those with few animal handling touch points, such as pasture/ grass-based cattle production systems. At any one time 96% of the cattle population in Australia, the United States, Brazil and New Zealand graze grass. There are currently no methane-reducing additives commercially available for these cattle. “We are very pleased with these results as they build on the significant trial data set that Rumin8 has generated with a range of formulations in a variety of production systems over the past three years," says David Messina, Rumin8 Chief Executive Officer. “With so many cattle grazing grass around the world, the 81 per cent methane yield reduction achieved through water-based delivery was truly exciting, both in terms of addressable market and the positive climate impact this has the potential to create." Read more>> New Study: Water supplemented with Rumin8 reduces methane by 81%

NEWS FEED & ADDITIVE MAGAZINE July 2024 21 This new science changes everything we thought we knew about choline’s impact on the cow and her calf. The ReaShure family of products is the original and most researched rumen-protected choline source, so you can be sure you’re getting the benefits you expect. Trust ReaShure and Balchem to deliver, across generations. Visit Balchem.com/ReaShure-XC to learn more. “ Choline is a Required Nutrient for Essentially Every Cow SCIENTISTS SAY: Is choline essential or required? I think it’s required and we should be framing out a requirement in our nutrition models. -Dr. Mike Van Amburgh, Cornell Nutrition Conference, 2022 Choline plays an important role in metabolic health. Multiple studies have shown ReaShure’s impact on transition cow health. -Dr. Marcos Zenobi, Research Study from 2018 “ “ “Certainly, Rumen-Protected Choline appears to have some new opportunities to be placed in high- producing dairy cow rations and may impact animal health during the transition. -Dr. Mike Hutjens, Mikehutjens.com Even in very high-producing cows, we saw a milk response of approximately 2,3 kg/cow/day after supplementation. -Dr. Heather White, Tri-State Dairy Nutrition Conference, 2023 Choline dramatically increased colostrum yield – an 85% increase in our study. -Dr. Barry Bradford, Tri-State Dairy Nutrition Conference, 2023 “ “ All trademarks are property of Balchem Corporation © 2024 Balchem Corporation. All rights reserved. 2405-001 Balchem ANH – EMEA Region Balchem Italia Via del Porto Snc 28040 Marano Ticino (NO) Italy Phone +39 0321 9791 E-mail [email protected] Website Balchem.com

NEWS 22 FEED & ADDITIVE MAGAZINE July 2024 Lallemand Animal Nutrition and the French research institution INRAE (National Research Institute for Agriculture, Food and Environment), through the MEDiS Research Unit located in the Clermont-Auvergne-Rhône-Alpes Research Center in France, renewed their 30–year research partnership with the signing of an Associated Partnership Laboratory (APL) agreement. This new agreement includes research into microbial solutions used in ruminant nutrition and health. Based on a common roadmap for five years, the APL will enable INRAE and Lallemand Animal Nutrition to pool their material and human resources around a co-designed research and technology program. This is a new type of partnership at INRAE, which aims to accelerate the development of innovations with flexibility and adaptability. The general objective of the APL is the study of the digestive microbiota of the ruminant and its interactions with microbial solutions developed by Lallemand and/or the APL, the characterization of the modes of action of these solutions, the technological developments allowing this characterization, and the isolation and screening of new microbial solutions for ruminant nutrition and health in the context of a changing environment and consumer concerns surrounding the sustainability of ruminant production, and on food safety. Read more>> Lallemand renews research partnership with French institute dsm-firmenich, an innovator in health, nutrition, and beauty, launched a shrimp module for Sustell™, allowing shrimp farmers to map, reduce the full environmental footprint of their operations and meet environmental sustainability targets. The new module offers on-demand environmental footprinting for shrimp production of all stages, from hatchery, to nursery, to grow out, in addition to a feed module which is a critical contributor to LCA in any animal farming system, explained dsm-firmenich. The new module was developed in collaboration with Grupo Almar, from Ecuador, one of the top 5 global shrimp producers who will be applying this technology across their farms as they look to deliver on their sustainability ambitions. “When we partnered with dsm-firmenich last year, we knew we wanted to implement technologies that help us improve the environmental sustainability of our shrimp production. We knew when we chose Sustell™ we would be able to go beyond measurement by taking ownership of our full environmental footprint, and now, with the new module for shrimp, we are able to take our sustainability efforts one step further,” said Wolfgang Harten, General Manager/COO of Grupo Almar. Read more>> dsm-firmenich unveils new module in Sustell for shrimp

NEWS FEED & ADDITIVE MAGAZINE July 2024 23 LEVUCELL SC rumen specific live yeast improves milk yields up to 6% and feed efficiency up to 7%. We have the science to prove it. LEVUCELL SC. No other yeast works the same. Not all products are available in all markets nor all claims allowed in all regions. naturally more productive

NEWS 24 FEED & ADDITIVE MAGAZINE July 2024 The 15th edition of AquaVision, organized by Skretting and its parent company Nutreco since 1996, gathered some 450 participants from more than 40 countries in Stavanger, Norway. The event addressed challenges and new opportunities for the aquaculture industry, such as sustainability, market disruptions, innovation and artificial intelligence. On the opening day of the event, new Nutreco CEO David Blakemore, having assumed the role just 10 days before, introduced himself to the room, and talked about Nutreco's role in feeding the world's rapidly growing population. "In Nutreco we have over a century of experience providing high-quality nutrition to the animal and aquaculture industry. Feeding the Future is not just our purpose, it's also our passion and responsibility," said Blakemore. The next speakers after David Blakemore dived into the topic of sustainability. Gonzalo Muñoz, UN Climate Change High-Level Champion for COP28, IUCN President, concisely summarised the severity of this challenge when he said early on in his presentation: "Getting to net zero by 2050 is massive. We've been really slow and things need to change exponentially." The stage for the second session on market disruptions was set by none other than the world-renowned economist Professor Paul Krugman. He gave a very interesting overview of the state of the world economy today, talking about the economic impacts of Covid-19 ("we've bounced back very quickly"), inflation, the influence of technology and artificial intelligence, climate change, globalisation, and of course, politics. Read more>> Aquaculture's challenges and opportunities discussed at AquaVision 2024 IFF announced EU-wide regulatory approval for two of its groundbreaking feed solutions for poultry. The company explained that Axtra® XAP – a multi-enzyme blend and Syncra® AVI – an enzyme-probiotic complex from Danisco Animal Nutrition & Health, IFF’s Health & Biosciences business unit, are formulated to meet the challenges of modern poultry production and deliver measurable performance improvements. “Obtaining full EU authorization empowers us to unleash the remarkable potential of these two exceptional in-feed products to poultry producers across the region,” said Jose Luis Ecija Roux, Marketing Director EMEA, Danisco Animal Nutrition & Health. “Axtra® XAP and Syncra® AVI have demonstrated their pivotal role in advanced feed strategies, and we look forward to helping our customers in maximizing this unprecedented opportunity.” According to a statement from IFF, Axtra® XAP, a high-performance xylanase, amylase and protease enzyme combination, increases energy efficiency and improves bird performance in both corn-based and mixed-grain diets. Through optimized nutrient availability, this unique feed solution enables greater flexibility in dietary formulations, significantly reduces feed costs and improving profitability1. Additionally, Axtra® XAP allows producers to adapt their operations to meet consumer demands and industry trends, including free-range production and the use of all-vegetable dietary ingredients. Read more>> IFF unveils approval of two feed solutions for poultry

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