ISSUE FOCUS 62 FEED & ADDITIVE MAGAZINE May 2024 Zinc chelates Published date Summary of EFSA Opinion 27 November 2009 23 March 2012 23 January 2013 10 November 2015 8 June 2017 25 July 2019 22 March 2021 21 February 2023 Studies involving piglets, laying hens, and dairy cows indicate this does not result in different Zn concentrations in muscle, liver, kidney, skin/fat, eggs, and milk compared to inorganic sources. Tissue deposition of this zinc source is expected to be similar to that of zinc sulfate. Data on Zn uptake and tissue deposition in species other than poultry do not suggest greater bioavailability than other authorized Zn sources. Tolerance studies indicate safety as a zinc source, with no distinct zinc deposition in edible tissues/ products compared to the standard inorganic source, Zn sulfate heptahydrate. Bioavailability comparable to Zn sulfate or ZnO in poultry, pigs, and ruminants. Based on Zn deposition across various tissues (e.g., tibia in chickens), it serves as a bioavailable Zn source, comparable to the standard inorganic Zn source, with no expected increase in zinc content in animal tissues and products. May contain multiple Zn species and not solely comprised of Zn mono-chelate of EDA; submitted combined tolerance, residue, or efficacy study in chickens for fattening was deemed invalid. Considering the deposition of Zn in edible tissues/ organs in chickens for fattening, the additive serves as a source of bioavailable Zn and is comparable to the standard inorganic Zn source. Zinc chelate of hydroxy analogue of methionine Zinc chelate of amino acids hydrate Methionine-zinc Zinc chelate of L-lysinate-HCl Zinc chelate of methionine sulfate Zinc chelates of lysine and glutamic acid Zinc chelate of ethylenediamine Zinc (II)–betaine complex Table 1. Zinc chelates and the summary of EFSA Opinions regarding their efficacy and bioavailability About Dr. Yron Joseph Y. Manaig Dr. Yron Joseph Y. Manaig, an animal nutritionist from Philippines/Spain, holds a master’s degree in animal nutrition from University of the Philippines Los Baños. He earned a European Joint Doctorate in Molecular Animal Nutrition (MSCA-ITN) from Universitat Autònoma de Barcelona (Spain) and Università degli Studi di Milano (Italy). Dr. Manaig specializes in swine nutrition, feed ingredient evaluation and formulation, and OMICS. He joined ANIMINE in 2023 and has been working with the R&D group since. About Marion Taris Marion Taris is currently the analytical project engineer of Animine Precision Minerals. She is a scientist specializing in chemical analysis. She studied chemistry and physics before specializing in chemical analysis. She graduated from the University of Pau (France). Between 2017 and 2021, she worked on the development of new strategies for the analysis of enzymes immobilized on electrodes for the French national center for scientific research (CNRS). Marion joined Animine in 2023 and has been working with the research and development group since.
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