ISSUE FOCUS FEED & ADDITIVE MAGAZINE April 2024 51 Suppression of NE-caused lesions Day 13 % NE lesion-free 70 100 120 100 80 60 40 20 0 100 100 57 55 100 80 Day 15 Day 17 Day 20 Figure 2. Preventive effect of Formycine Gold Px concerning necrotic enteritis gut lesions FCR Daily gain g/bird/day 35 40 35 30 25 20 15 10 5 0 3,00 2,50 2,00 1,50 1,00 0,50 0,00 28 2,05 2,85 2,26 36 non-infected and non-treated animals infected and non-treated animals infected animals, 2.0kg Formycine Gold Px/t of feed Figure 3a and 3b. Performance-maintaining effect of Formycine Gold Px equipment helps to reduce/avoid exposure. A combination of free acids and acid salts provides optimal hygienic effects Additionally, another blend of organic acids (Acidomix AFG) shows the best effects against representatives of relevant feed-borne pathogens in poultry. In a test, 50 µl solution containing different microorganisms (reference strains of S. enterica, E. coli, C. perfringens, C. albicans, and A. niger; concentration 105 CFU/ml, respectively) were pipetted into microdilution plates together with 50 µl of increasing concentrations of a mixture of organic acids (Acidomix) After incubation, the MIC and MBC of each pathogen were calculated. The test results show (figure 4, Minimal Bactericidal Concentration) that 0.5% of Acidomix AFG in the medium (≙ 5kg/t of feed) is sufficient to kill S. enterica, C. albicans, and A. niger and even only 2.5kg/t in the case of E. coli. If the pathogens should only be prevented to proliferate, even a lower amount of product is requested (figure 5, Minimal Inhibitory Concentration - MIC). In addition to the direct antimicrobial effect, this product decreases the pH of the feed and reduces its buffering capacity. The combination of free acids and acid salts provides prompt and long-lasting effects.
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