ARTICLE 68 FEED & ADDITIVE MAGAZINE March 2024 Depending on your region, you also can use an innovative probiotic, PROTERNATIVE, to help calves become more resilient in the face of stress, which helps them reach their highest potential, maintain performance and help support well-being. The probiotic effects of PROTERNATIVE are derived from the live yeast, and it helps balance the calf gut microbiota, interacting with the gut epithelium and promoting the gut immune system production of immunoglobulin. The effects were observed in a study where the IgA production was followed into ileum and colon during supplementation with the live yeast. CONCLUSION In calves, the first months of life are critical for future production. Nutrition management is key to limiting the impact of early stresses on the digestive system and ensuring optimal rumen development. In addition to good management practices, producers can include beneficial nutritional tools to help maintain calf health, support starter intake and reinforce rumen papillae development for optimal adult performance. Well-researched tools include probiotic live yeast such as LEVUCELL SC and innovative yeast fractions such as YANG. References 1. Abuelo A., C. Faith, A. Hanes, J. L. Brester. 2021. Impact of 2 Versus 1 Colostrum Meals on Failure of Transfer of Passive Immunity, Pre-Weaning Morbidity and Mortality, and Performance of Dairy Calves in a Large Dairy Herd Animals11(3), 782. 2. Bach A. and Ahedo J. 2008. Record Keeping and Economics of Dairy Heifers. Vet Clin Food Anim 24: 117–138 3. Bittar C.M. and Ferreria L. 2007. Avaliação da suplementação com culturas de levedura (Saccharomyces cerevisae) para bezerros leiteiros: crescimento do trato digestório e desenvolvimento do rúmen . Annual Meeting of the Brazilian Society of Animal Science (poster) 4. Chaucheyras-Durand F. and G. Fonty. 2001. Establishment of cellulolytic bacteria and development of fermentative activities in the rumen of gnotobiotically-reared lambs receiving the microbial additive Saccharomyces cerevisiae CNCM I-1077. Reprod. Nutr. Dev. 41: 57-68 5. Chaucheyras-Durand F. and G. Fonty. 2002. Influence of a probiotic yeast (Saccharomyces cerevisiae CNCM I-1077) on microbial colonization and fermentations in the rumen of newborn lambs. Microb. Ecol. Health Dis. 14:30-36. 6. Dairy Calf and Heifer Association (DCHA) Gold Standards, Second edition (2016) 7. Urie N.J., E. Lombard, C.B. Shivley, C.A. Kopral, A.E. Adams, T.J. Earleywine, J.D. Olson, F.B. Garry. 2018. Preweaned heifer management on US dairy operations: Part V. Factors associated with morbidity and mortality in preweaned dairy heifer calves. Journal of Dairy Science 101(10):9229-9244. Learn more about interleukins: Interleukins act as mediators to modulate the immune response. IL-10 is an anti-inflammatory cytokine. IL-6 is involved in pro-inflammatory responses. Figure 4. Interleukins gene expressions coming from gut sample of preweaned calves. Figure 5. Immunoglobulin concentration (measured through SIgA concentration into ileum and colon)
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