ISSUE FOCUS FEED & ADDITIVE MAGAZINE March 2024 53 OUR APPROACH While studying the adverse effects of mycotoxins on ruminal conditions and digestibility, we were able to demonstrate the protective efficacy of Mycofix®. Although numerous products in the market assert their ability to bind mycotoxins, the mycotoxins investigated in the recent scientific trials vary significantly and cannot be effectively addressed using a one-size-fits-all approach. CONCLUSION Mycotoxins have the potential to limit both beef and dairy productivity through various mechanisms: (1) diminished feed intake, suppressed microbial activity, and (2) reduced digestibility of DM (Dry Matter) and (3) NDF (Neutral Detergent Fiber). For ruminant experts seeking improved productivity, a key piece of advice is to first ascertain whether mycotoxins are constraining the achievement of your goals. Once mycotoxins have been addressed, consider implementing the right management, nutritional, and technological strategies to enhance performance. References 1. Duringer, J.M., Roberts, H.L., Doupovec, B., Faas, J., Estill, C.T., Jiang, D. and Schatzmayr, D., 2020. Effects of deoxynivalenol and fumonisins fed in combination on beef cattle: health and performance indices. World Mycotoxin Journal, 13(4), pp.533-543. 2. Gallo, A., Minuti, A., Bani, P., Bertuzzi, T., Cappelli, F.P., Doupovec, B., Faas, J., Schatzmayr, D. and Trevisi, E., 2020. A mycotoxin-deactivating feed additive counteracts the adverse effects of regular levels of Fusarium mycotoxins in dairy cows. Journal of Dairy Science, 103(12), pp.11314-11331. 3. Kiyothong, K., Rowlinson, P., Wanapat, M. and Khampa, S., 2012. Effect of mycotoxin deactivator product supplementation on dairy cows. Animal production science, 52(9), pp.832-841. 4. Wu, W., Zhou, H.R., He, K., Pan, X., Sugita-Konishi, Y., Watanabe, M., Zhang, H. and Pestka, J.J., 2014. Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicological Sciences, 138(2), pp.278-289. About Ignacio Artavia Ignacio Artavia holds a bachelor's in Agriculture Sciences and a master's in Sustainable Animal Nutrition and Feeding. He´s the global marketing manager for ruminants at dsm-firmenich, and has supported farmers, nutritionists, and health experts to overcome the negative impact of mycotoxins in different parts of the world. DM digestibility NDF digestibility 60 55 50 45 40 35 75 70 65 60 55 50 52,3b 71.0b 67,3c 72,4a % % 42,8c Control MTX MTX + MPL Control MTX MTX + MPL Treatments (21 days each) Control MTX MTX + MPL Don (ppb) 300 800 800 1100 1100 0 35 100 0 Fum (ppb) MPL (g/head/day) 53,6a
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