ISSUE FOCUS 40 FEED & ADDITIVE MAGAZINE March 2024 This metabolite's structural similarity to oestradiol enables it to bind to specific cell receptors, potentially leading to various reproductive complications. However, disruptions in rumen function, often attributable to high dry matter intake in cows, can impede the detoxification process by rumen microbes. Moreover, certain mycotoxins, like patulin, possess antimicrobial or anti-protozoal properties, further hindering rumen microflora's ability to neutralize mycotoxins, consequently facilitating their absorption into the organism. MITIGATING RISKS Addressing mycotoxin contamination in ruminant feed necessitates a multifaceted approach, given the pervasive nature of multi-contamination. No single method ensures foolproof mycotoxin control. Therefore, implementing a robust risk management program becomes imperative, encompassing optimal agricultural practices in cultivation (such as high-quality seed selection, crop rotation, and effective management of crop residues), during harvest (adhering to proper harvesting procedures, removal of high-moisture plant parts), and in storage (regulating moisture levels, employing humidity control measures, and incorporating chemical preservatives). Notably, as many mycotoxins maintain stability throughout storage and processing, proactive measures are essential. Furthermore, integrating well-selected antibiotoxin solutions directly into feed presents a promising strategy to mitigate mycotoxin risks. These solutions protect the animals by providing different mode of action: adsorption of the consumed mycotoxins in the gastrointestinal tract, biodegradation, and bioprotection. This biological approach is promising because it is environmentally friendly and cost-efficient. PROMISING RESULTS A recent trial carried out on a commercial farm in 2021 in France showed positive results on the action of such in-feed solution. This study involved 70 lactating Holstein dairy cows fed a diet supplemented with Multiprotect Y, an anti-biotoxin solution, for 60 days. Analysis of mycotoxin contamination in the Total Mixed Ration (TMR) revealed low but multiple mycotoxin contamination (with DON, FUM, ZEA, H-T2 toxin and tenuazonic acid) throughout the study period . Supplementation with Multiprotect Y led to improvements in inflammatory status and liver functions in dairy cows. Furthermore, supplementation with Multiprotect Y resulted in increased excretion of tenuazonic acid, indicating improved liver function. Finally, a calculated gain of 0.8 kg milk per cow per day was observed with the supplemented diet, considering milk production persistency at 93.7%. The findings of this study demonstrate the beneficial effects of supplementing dairy cow diets with Multiprotect Y in improving immunity, sanitary status, and zootechnical performance. The results underscore the importance of monitoring biomarkers for evaluating mycotoxin exposure and understanding its effects on dairy cow health and productivity. About Anne-Laure Tournay Graduated with an Agricultural Engineering Master’s degree, Anne-Laure Tournay has a solid experience in marketing acquired within various international agricultural companies. She joined MiXscience in September 2019 as In Feed Solution Product Manager. She is in charge of the development and marketing of two solutions portfolios: the Rabbit range, and the Multiprotect range dedicated to issues related to biotoxins.
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