Feed & Additive Magazine Issue 37 February 2024

February 2024 Year: 4 Issue: 37 Feed Additive INTERNATIONAL MAGAZINE FOR ANIMAL FEED & ADDITIVES INDUSTRY Kevin Perryman, Selko The role of minerals in rumen digestion Dr. Hugo Romero, Novus Why does hatchability decrease and how can it be increased? Dana Tomlinson, Zinpro The essential nutrients that drive fiber digestibility www.feedandadditive.com Digestibility & Feed Conversion Ratio & Precision Nutrition Global Feed Enzymes Market

Farmers' voices are echoing loud and clear in the heart of Europe. Recent farmers’ protests across the continent shed light on the challenges facing the agriculture industry and its wider impact on society. At the root of the problems are countries' agricultural policies, environmental regulations and increasing economic challenges. Farmers are calling for the attention of both policymakers and the public, reminding them of the reforms that will shape the future of agriculture and calling for more sustainable and humane practices. These concerns driving farmers to action cannot be ignored. Pressured by low crop prices, rising input costs and tightening environmental regulations, many farmers fear losing their livelihoods. Drought and volatile markets rub salt to the wound. Still, their demands go beyond short-term solutions. They want fairness in the food chain, sustainable practices and recognition of their strategic role as stewards of the land. Understanding their demands and focusing on solutions will not only benefit farmers and their livestock, but also contribute to sustainable food production and the overall health of the planet. These protests also provide an important opportunity for experts in the animal nutrition industry to reconsider many issues and redesign the role of the industry. For example, prioritizing sustainable feed sources and promoting local production could be an important topic to consider. Encouraging investments in alternative feed sources such as insects, algae and fermentation products, which have great potential, could facilitate farmers' access to new sources that are economical and beneficial. Diversifying feed ingredients and minimizing food waste through different options can increase the resilience of farms and reduce environmental impact. Similarly, promoting precision nutrition is also one of the leading options. Tailoring rations to the individual needs of animals can optimize health, reduce waste and address ethical concerns. And of course, the most important issue should be to defend fair competition. Supporting policies that ensure farmers receive a fair share of the food value chain is the most valuable support for their indispensable role in our lives. A fair system where farmers are compensated for their valuable labour and treated with the respect they deserve is possible. It should be possible... Enjoy your reading! Hope to see you in the next issue! Publisher Muhammed Akatay [email protected] Responsible Manager Özlem Akatay [email protected] Editor-in-Chief Derya Yıldız [email protected] Editors Bahadır Büyükkılıç Burak Varol [email protected] Communication & Marketing Lisa Atakul [email protected] Design Alper Kandemir [email protected] Web Design Caner Cem Pulat [email protected] Circulation and Data Responsible Amine Şengün [email protected] Ataturk St. Metropol Istanbul Ste. Block C1, No:376 Atasehir, Istanbul/TURKEY Phone: +90 850 220 5064 E-Mail: [email protected] Web: www.feedandadditive.com Publication Type: Periodic (Monthly) EDITOR Farmers’ Protests: A Call for Sustainable Animal Nutrition Derya YILDIZ © Three Plus Media | All rights reserved. Reproduction, in whole or in part, is prohibited without the written permission of the publisher. *DISCLAIMER: All views and ideas expressed in articles published in the magazine reflect the point of views of the author(s), not that of the Editor-in-Chief, Editors, Editorial Board or Publisher of Feed & Additive Magazine. The Editor-in-Chief, Editors, Editorial Board and Publisher assume no responsibility or liability in such cases. The publisher does not give any warranty and representation to the accuracy or completeness of the contents and data published in the magazine. All responsibility of the contents, articles and information published in the magazine belongs to the authors. The publisher and the authors cannot be held responsible for any damages resulting from the use of the whole or part of the content of the magazine. feedandadditive

Optimizing rumen digestibility is a priority when working to maximize the productivity, efficiency, and sustainability of high performing dairy herds. Selko® IntelliBond® is the first family of improved trace mineral nutrition products to support livestock producers with improving NDF digestability while lowering the carbon footprint. Improve NDF digestibility while lower your premix sustainability footprint? IntelliBond, the first trace mineral source with a verified Life Cycle Assessement Learn more, visit www.ruminants.selko.com

4 FEED & ADDITIVE MAGAZINE February 2024 As an association, FEFAC wants to be the voice of the European compound feed and premix industry. In that sense, our main challenge is to engage the current and potential new members in the common targets for the feed industry in Europe, defining our statements in a way that makes the members feel comfortable. Our purpose is to give more value to what we do as a responsible and essential activity, highly regulated and controlled, as well as to what we contribute to society in terms of employment, sustainability, circularity, support for livestock and aquaculture production, which is our reason for being and a key element for life in rural areas, and therefore our contribution to the production chain of safe, healthy, and nutritious food for the people. I am deeply convinced that we should be aligned and well-coordinated not only internally but also with the rest of the players in the food chain (suppliers, farmers, etc.) to give a common message. This common message has more strength and is heard more clearly by both policymakers and the rest of society. Part of our mission is to contribute to the development of harmonized and reasonable regulatory frameworks. Through a true cross-sectoral partnership in close cooperation with policymakers, we should go one step up. That means increasing the productivity and sustainability of our activities, collecting and managing data to determine our impact using a fact-based approach, and implementing actions to go into a new era of protein production in Europe. All the initiatives to reduce our impact and external dependency are more than welcome. Innovation is more relevant than ever, as we should speed up the solutions. This is something that takes time and needs public and private resources and legislative support, but is doable. Sustainability and circularity are two of the main topics in which we want to be very active. FEFAC has a great opportunity to play a relevant role by providing tools and support together with our supply chain partners, which will enable the EU livestock and aquaculture sector to achieve most of the relevant objectives of the EU sustainability expectations. However, this cannot imply a radical reduction or elimination of animal protein production. We must contribute to implementing the best production practices that are sustainable, not only from an environmental point of view but also from a socioeconomic perspective. Europe should not repeat mistakes from the past, where production sectors were simply exported and import dependency increased. In that sense, FEFAC welcomes the Open Strategic Autonomy proposed during the Spanish Presidency, which was well received in the Granada Declaration by all the member states. 2023 was a year of transition, with a number of achievements at the global level, like COP28, and at the European level, the adoption of important legal acts such as the deforestation regulation, which is a breakthrough in the way the EU wants to position itself in sustainable trade development while looking for EU strategic autonomy. 2023 saw FEFAC taking a step in the implementation of the FEFAC Feed Sustainability Charter 2023, which was published in 2020, with the publication “Advanced Animal Feed Strategies to Support the Transition towards More Sustainable and Circular Livestock and Aquaculture Production”. The objective is to facilitate access for chain partners and decision-makers to sound scientific-based information on the techniques themselves, how they work, and for which species, as well as some considerations on the economic impacts and trade-offs. Practical case studies showcasing existing animal feeding strategies are now available online on the FEFAC website. Regarding circularity, we should recognize that the feed A NEW ERA OF PROTEIN PRODUCTION IN EUROPE Pedro Luis Cordero Castillo FEFAC President CESFAC (Spain) Vice-President LEAD ARTICLE

FEED & ADDITIVE MAGAZINE February 2024 5 industry is always at the forefront of the circular economy and the optimization of available resources. There are some fundamental aspects on which the sector should focus. First, to communicate as much as possible about the “circular” concept. Co-products are the resulting feed materials derived from a process where the main activity is geared towards the production of a different consumer product, such as beverages, food, biofuels, or other industrial applications. Their existence is an unavoidable consequence of the lead process, but they are nonetheless extremely valuable in animal nutrition. The European feed industry takes great pride in the knowledge, understanding, and technical capacity that it has built up on how to recover nutrients from these non-human edible materials. Linked to this approach to human inedible feed, FEFAC has highlighted the role of the compound feed sector in the circular economy thanks to the use of co-products. Using it, the compound feed sector makes a fundamental contribution to sustainable food systems, reducing food waste along the supply chain and keeping valuable nutrients that would otherwise be lost. This is a concept that our grandparents knew very well and that our industry develops professionally, ensuring the nutritional value, quality, and safety of these co-products. Secondly, FEFAC invites regulators to proceed with a systematic review of legislative bottlenecks in the EU regulatory framework that currently restrict a higher level of circularity in EU food systems through innovative animal nutrition solutions that can benefit sustainability targets. Last but not least, we should highlight that the role of the animal nutrition industry and livestock sectors in the circular economy, with their capacity to absorb residual biomass from other (industrial) food and non-food sectors, should not enter into competition with the efforts to enhance the sustainability of energy production with the use of advanced biofuels that can impact the competitive access of the feed sector to residual biomass flows in the future. This is particularly relevant due to the current circumstances of the Ukraine war’s impacts on energy costs in the EU. FEFAC also raised further attention to the possibly conflicting dynamics between increased biomethane production and increased circular feed availability. Due to stimulation policies, there is a perceived risk that there are financial incentives that divert the resources we consider circular feed towards biomethane production as a form of renewable energy. FEFAC has initiated discussions with a wide variety of stakeholders to discuss the development of an EU biomass factsheet and to bring more transparency to the discussion. There are other relevant topics or bottlenecks on which we also want to be very active. In July 2023, the European Commission published its proposal on the NGTs regulation, amending the current one from 2017. In principle, FEFAC welcomes the differentiation of conventional-like NGTs from classical GMOs and the exemption from authorization and labelling requirements for a group of those NGT plants (category 1) for which no risk assessment has to be made and they can be labelled in the same way as conventional plants. This is a relevant advance, but we are still concerned by the practical enforcement of the proposed measures for another group of them (category 2), in particular those for which no method of detection is available, and, in addition to that, the use of the NGT´s in organic production. However, it remains a sensitive topic, with a lot of resistance from some civil society organizations. We will need academic experts to proactively engage in the public debate to demonstrate the benefits of what these kinds of innovations can offer to be able to see a favourable political environment develop in favour of a political agreement that indeed would allow NGTs in European agriculture to make a positive contribution. The EU feed market in 2023 reflected continued political and market crisis management pressures and a growing demand for providing sustainable feed solutions to address market dynamics and regulatory considerations. These trends are a response to the adverse impacts of climate change on the supply of raw materials, such as droughts and floods, and on animal production capacity, including Avian Influenza (AI) and African Swine Fever (ASF). Additionally, national policies ranging from greenhouse gas reduction goals to nitrate emission regulations have contributed to these shifts. In these six months as president, many challenging things have happened in our market due to geopolitical matters, climate change impacts, etc. The current situation in the Ukraine war, the instability and uncertainty of the markets, some potential disruptions (one more) in the supply of certain raw materials or products due to the recent conflicts in the Middle East, EU regulations that impact our sector or related sectors, and the extremely high pressure on animal production, among others, are important enough reasons to dedicate time to all of them. Together with the FEFAC team and our colleagues in the different bodies of the association, we will try to improve our support for this strategic sector for the benefit of our EU citizens.


CON T E N T S 66 INFLUENCE OF FEEDING LEVEL ON ENERGY DISTRIBUTION Megha S Vinod, Central Institute of Fisheries Education, Mumbai 72 INSECT MEAL: AN ALTERNATIVE FEED RESOURCES FOR POULTRY Priyanka Kumari & Pranit V. Mankhair & Pankaj Kumar Singh Bihar Veterinary College, Bihar Animal Sciences University ARTICLES MARKET REPORTS GLOBAL FEED ENZYMES MARKET 76 GRAIN REPORTS GLOBAL CORN SUPPLY AND DEMAND & 2024 EXPECTATIONS 80 Novonesis becomes a leading global biosolutions partner 16 Dairy farmers get carbon-asset payments for emissions reductions 84 dsm-firmenich extends Sustell to cover sea bass and sea bream 10 Adisseo announces new plans for methionine production 14 Kemin achieves FDA approval for chromium propionate 12 Selko launches natural performance enhancer Fytera Perform 22 NEWS EntoGreen to produce 25 tons of larvae per day with WEDA feeding system 88 Darling Ingredients completes acquisition of Miropasz 97 57 BENEFITS OF AQUATIC ANIMAL WELFARE FOR SUSTAINABILITY Christine Xu & Sophika Kostyniuk, Aquatic Life Institute 62 THERE’S A FUTURE FOR PALM OIL IN THE DAIRY SUPPLY CHAIN, BUT SUSTAINABLE SOURCING MATTERS Dr Richard Kirkland, Volac & Catherine Barton, Chester Zoo. SUSTAINABILITY

NEWS 8 FEED & ADDITIVE MAGAZINE February 2024 ADM, a global leader in sustainably sourced solutions from nature, loaded and shipped its first vessels of verified, fully traceable soybeans from the U.S. to Europe. With the completion of the initial phases of the programme, and in anticipation of the new EU deforestation regulations becoming effective at the end of the year, ADM now intends to expand these capabilities to other key locations across North America in the 2024 growing season. “At ADM, our future and success depend on the farmers we work with and for, which is why we’re committed to helping support their businesses and their legacies by ensuring that global markets remain open to U.S. agricultural products,” said Matt Hopkins, ADM’s vice president, North America River, and Export. “This programme, along with our comprehensive plan to achieve 100% deforestation-free supply chains by 2025, demonstrates the value of ADM’s irreplaceable global footprin1t and our investments in climate-smart and regenerative agriculture.” “While there are still issues – including how full compliance will be defined, measured, and enforced – to work through in advance the EU’s deforestation regulations, we are confident in our ability to continue to deliver to customers in Europe,” said Jon Turney, ADM’s vice president, EMEA Crush. “We will continue to work with stakeholders – including farmers, government, and industry – across our supply chains in the U.S. and other key regions between now and the new regulations coming into effect on December 31.” Read more>> ADM expands traceable soybean pilot Ÿnsect receives approval to commercialize mealworms in US Ÿnsect, one of the strongest players in the production of insect-based proteins, has been granted authorization by the AAFCO (Association of American Feed Control Officials) to use defatted mealworm proteins in dog nutrition. It is the first time that mealworm-based ingredients for pet foods have been approved in the USA. The authorization follows two years of evaluation by AAFCO, the organisation responsible for the safety of animal food in the USA. Approval was granted to Ÿnsect based on a comprehensive scientific dossier that included a 6-month trial introducing mealworm-derived ingredients into the diet of dogs. The results demonstrated the safety of the product and its nutritional benefits. A further study commissioned by Ÿnsect with Professor Kelly Swanson from the Animal Sciences Laboratory at the University of Illinois' Urbana-Champaign, proved that the protein quality of defatted mealworm flour from Tenebrio molitor was comparable to high-quality animal proteins traditionally used in pet food manufacturing, such as beef, pork, and salmon. “We are very proud to have obtained the very first authorization for the commercialization of mealworm-based ingredients for pet food in the United States. It is the recognition of over 10 years of research for the benefit of animal health. This authorization opens the doors to the immense American market just as we are preparing to deliver our first pet food customers from our Amiens farm,” said Shankar Krishnamoorthy, CEO of Ÿnsect. Read more>>

NEWS FEED & ADDITIVE MAGAZINE February 2024 9 Ittinsect secures €600,000 in funding for sustainable protein production Ittinsect secured over €600,000 in non-dilutive funding from Invitalia, Italy’s Development Agency. This funding will facilitate the construction of a pilot plant capable of producing 2,300 metric tons of sustainable proteins annually. This marks a key step toward the biotech company's goal of scaling up to an industrial-scale production of proteins derived from 100% circular economy processes by 2025. This initiative highlights the importance of scaling up sustainable aquafeed for safeguarding our oceans, according to the company. Ittinsect will deploy €602,500 to build a section of its inaugural production facility. The facility will prove both the technical and economic advantages of Ittinsect's products at scale, laying the groundwork for the company's first industrial plant. This scale-up will also bolster the recruitment of specialized personnel and the pursuit of new patents, solidifying Ittinsect's position as the preeminent innovator in the market. Ittinsect’s CEO, Alessandro Romano, underscored the significance of national support from Italy’s National Development Agency, stating, "We are honored to secure this funding, building upon the trust already received from the Lazio Region during the project's pre-seed phase. The backing from Invitalia confirms the regional interest has transcended into a national one. Our goal is now to extend public support to an international level." Read more>> Cargill launches new non-invasive NIR technology REVEAL™ Layers Cargill launched REVEAL™ Layers, a first-of-its-kind, non-invasive NIR technology to monitor the body condition of poultry. This patent-pending breakthrough technology empowers producers to optimize laying persistency and egg production. Using Cargill’s innovative, non-invasive Near-InfraRed (NIR) technology, producers and nutritionists have immediate access to body composition assessments of their hens. This allows them to make real-time decisions regarding diets to support their flocks’ long-term production and performance. It is believed that overdeveloped fat pads in laying hens are problematic for long-term egg production and optimal liver function. Cargill’s REVEAL™ Layers uses NIR light technology to measure the bird’s fat pads. The results are then uploaded and analysed, providing producers and nutritionists with actionable data which can be used to adapt the diet to achieve the optimal layer body composition. Not only could this trim feed costs, but it can also maximize egg production and boost profitability, setting a new standard in supporting the long-term performance of laying hens. “REVEAL™ Layers is part of Cargill’s holistic approach to monitor body fat and egg production, supporting the producer and nutritionist to make educated decisions regarding the diet. As we navigate the challenges of feeding a growing global population, these insights pave the way for more sustainable and efficient poultry production,” explains Lieske van Eck, Senior Scientist at Cargill. Read more>>

NEWS 10 FEED & ADDITIVE MAGAZINE February 2024 dsm-firmenich, the leading innovator in health, nutrition, and beauty, launched a marine fish module for Sustell™, allowing aquaculture producers of sea bass and sea bream to map the full environmental footprint of their operations. In 2022, dsm-firmenich launched Sustell™ for salmon, with leading salmon producer Bakkafrost as a development cooperation partner. Backed by robust methodology, ISO certification, and data connectivity, Sustell™ is the leading life cycle assessment (LCA) solution for animal protein, according to the company. dsm-firmenich emphasizes that Sustell™ provides the food value chain with a credible, science-based approach to collecting farm data, measuring the environmental footprint, and mapping a course for further development of the animal protein industry. Louise Buttle, Sustell™ lead for Aqua & Global Key Account Manager at dsm-firmenich, stated, “Now marine fish producers of species such as salmonids, seabass, and sea bream can conduct full life cycle assessment at scale, ensuring a strong return on investment and providing a credible and accurate footprint and a great user experience! Extending the Sustell™ platform to include sea bass and sea bream is a demonstration of dsm-firmenich’s commitment and continued innovations to further develop the sustainable production of seafood through aquaculture.” Read more>> dsm-firmenich extends Sustell to cover sea bass and sea bream Business Finland has conditionally approved a recycling and reuse investment grant of more than €12 million for biotech startup Enifer to build its first commercial-scale PEKILO® mycoprotein ingredient factory. The funding comes from the European Union NextGenerationEU recovery instrument. It will support building first-of-its-kind industrial facilities promoting the reuse and recycling of industrial by-products and waste streams, hence aligning with the EU’s circular economy action plan and the Sustainable Growth Programme for Finland. The commercial-scale factory will produce Enifer's unique PEKILO® mycoprotein ingredients, which are made using fungal fermentation. The PEKILO® fermentation process has a long legacy; it was originally developed by Finnish forest industry engineers in the 1970s. As the world’s first commercial mycoprotein production process from 1975 to 1991, it converted forest industry by-products into sustainable feed protein for the domestic market. The new facility will have a production capacity of 3 million kilograms a year of sustainable, locally sourced protein -roughly equivalent to the protein content of meat from 30,000 cows- but with at least 20 times lower carbon emissions and considerably lower water and land use. The factory is currently projected to cost €30 million to build and is expected to be completed by the end of 2025, with production ramp-up occurring in 2026. Read more>> Enifer builds first-of-its-kind mycoprotein ingredient factory

NEWS FEED & ADDITIVE MAGAZINE February 2024 11 Learn more at dsm.com/anh Symphiome™ Microbiome managed precisely When it comes to optimal gut health, the microbiome should function like an orchestra playing in perfect harmony. Conducting this orchestra is Symphiome™, a unique firstof-its-kind Precision Biotic. Symphiome™s unique mode of action increases metabolic functions intrinsic to the bird’s microbiome that detoxify unabsorbed amino acids and leaked host protein independent of the microbiota composition. Symphiome™ is the first-of-its-kind Precision Biotic that optimizes your birds’ resilience to enteric stress, aids in nutrient utilization, improves welfare, and reduces emissions. Symphiome™. Microbiome managed precisely Improves Welfare Optimizes Resilience to Enteric Stress DIGESTIVE Reduces Emissions Aids Nutrient Utilization If not us, who? If not now, when? We Make It Possible

NEWS 12 FEED & ADDITIVE MAGAZINE February 2024 Kemin Industries, a global ingredient manufacturer that strives to sustainably transform the quality of life every day for 80 percent of the world with its products and services, conducted extensive research that served as the basis for the U.S. Food and Drug Administration (FDA) Center for Veterinary Medicine's approval of the use of chromium propionate as a source of chromium in growing turkey diets. With this approval, chromium propionate is now approved for use in swine, broiler chickens, cattle, horses, and growing turkey diets. KemTRACE® Chromium from Kemin is the only FDA-reviewed source of chromium propionate on the market today and has been fed to millions of animals around the globe. According to the Kemin statement, KemTRACE Chromium is a highly bioavailable, organic source of chromium propionate that helps stabilize insulin receptors in animals, improving glucose utilization and reducing the negative impacts of stress. Every cell in the animal relies on glucose to fuel its function and growth, so maximizing cells' utilization of glucose may result in improved immune response and overall health and performance. "We are thrilled that the use of chromium propionate in animal diets continues to expand in the U.S. and beyond," said Kristi Krafka, Vice President of Regulatory Affairs and Quality Assurance, Kemin Animal Nutrition and Health – North America. "Kemin has spent decades advancing the nutrition and performance of livestock and poultry through novel feed ingredients and is now able to offer safe, effective KemTRACE Chromium to turkey producers, nutritionists, and veterinarians." Read more>> Kemin achieves FDA approval for chromium propionate Protix to construct new production plant in Poland The European Investment Bank (EIB) has committed to supporting Protix in the expansion of its sustainable protein production. The signing of the loan agreement marks a significant milestone, providing Protix, a producer of sustainable protein used for animal feed and pet food, with up to €37 million in additional funds for its international rollout. This agreement is in line with the InvestEU objective of a Sustainable Bioeconomy and Circular Economy and was made possible with the support of the InvestEU programme, which aims to trigger more than €372 billion in additional investment in the European Union over the period 2021-27. EIB Vice President Teresa Czerwińska said: “Supporting innovative solutions is one of the priorities of the European Investment Bank, and we are pleased to start collaborating with Protix. This financing is supported by the InvestEU programme and will enable the company to expand its activities and to apply its technologies, which contribute to the sustainable development of solutions within the bioeconomy sector.” Protix CFO Lynn De Proft said: “We are thrilled about this agreement with the EIB, not only for the opportunities it brings for further expansion but also as a resounding affirmation. This support reinforces the fact that our industry is not just here to stay but is poised for significant growth. Following our expansion to the United States and now our ability to do the same in Poland, we are excited to accelerate our mission to bring the food system back in balance with nature." Read more>>

NEWS FEED & ADDITIVE MAGAZINE February 2024 13 Bond Pet Foods shipped its first two metric tonnes of animal protein created through fermentation to Hill’s Pet Nutrition, which will begin to formulate test products using the innovative, more sustainable ingredient for regulatory review and market evaluation. Separately, the companies announced a second joint development agreement to create an additional animal protein for potential use in Hill’s products. The collaboration between Bond and Hill’s, announced in late 2021, aims to develop a source of more sustainable animal protein to fulfil the dietary needs of dogs and cats. The two metric tonnes produced by Bond represent a major milestone towards commercialising its fermentation technology for pet food applications. The scale of the delivery will allow Hill’s to formulate a variety of products at its Pet Nutrition Centre in Topeka, KS, for evaluation. That data will be used for the ingredient’s eventual review by the U.S. Food and Drug Administration’s Centre for Veterinary Medicine, as well as to prepare prototypes for market evaluation. “Hill’s is known for its leadership in precise, complete, and balanced, science-based nutrition. We are excited to continue our relationship with Bond and support their truly novel approach to producing animal proteins in a more sustainable way that meets our high-quality standards,” said Dave Baloga, Executive Vice President of Science & Technology for Hill's Pet Nutrition. Read more>> Fermentation-based animal protein being tested in pet food Selko, the feed additives brand of Trouw Nutrition, presented data from a trial evaluating the performance and economic effects of different water acidification strategies during the International Production & Processing Expo (IPPE) on January 30, in Atlanta, GA, U.S.A. While water acidification is a common practice used on poultry farms to support zootechnical performance, the application strategy varies across operations. Some farms provide flocks with a continuous supply of acidified drinking water, while other farms apply drinking water acidifiers on an intermittent schedule. Selko conducted a trial to compare the performance effects and economics of a synergistic blend of free and buffered organic acids (Selko AlpHa) applied in drinking water on a continuous or intermittent basis. The organic acid blend that reduces the pH of drinking water is designed to support nutrient digestibility and a stable intestinal microbiota. Performance improvements were considered through an economic lens to evaluate the return on investment of continuous application, partial application, and no application. During an oral presentation at IPPE regarding the trial, Global Category Manager Health & Performance José Manuel de la Fuente noted, “Trial findings show that supplementing poultry drinking water with the organic acid blend enhanced broiler performance without negatively affecting birds’ water intake.” He also remarked on the benefits of supplementing across the full cycle, stating, “Despite the lower initial investment with the reduced application of organic acid compared to application across the entire cycle, the economic return is considerably better for a continuous use strategy.” Read more>> Selko shares performance and economic effects of different water acidification strategies

NEWS 14 FEED & ADDITIVE MAGAZINE February 2024 Following several acquisitions, including Klifovet, Pen & Tec Consulting, and Ondax Scientific, Argenta rings in the new year by bringing its businesses together under one, energised brand. The combined identity reflects the company’s enhanced offering to customers, providing them with unparalleled, comprehensive support right across the animal health product development cycle from ‘molecule to market.’ According to the company's statement, Argenta already held a unique position as the world’s only combined CRO and CDMO dedicated to animal health, partnering with clients big and small for more than 17 years on the pathway from concept to market. The acquisition of Klifovet, Pen & Tec Consulting, and Ondax Scientific has strengthened this offering, and joining together under one brand reflects a determination to maximise the group’s collective capabilities and global footprint to help more clients improve the health of pets and livestock, and achieve their commercial goals. Argenta stated that the good news for customers is that there will be no changes to legal entities and who they do business with, and they’ll continue to work with the same experienced contacts at Argenta but will now have easier access to a greater range of expertise and capabilities as their requirements evolve. “As we’ve grown in recent years, we’ve brought some great companies into the group, expanding our offering to customers and strengthening Argenta’s position as the world’s only combined CRO and CDMO dedicated to animal health,” said Will Downie, CEO of Argenta. Read more>> Argenta combines legacy brands to further advance animal health Adisseo announces new plans for methionine production Adisseo, one of the world's leading manufacturers of feed supplements for animal nutrition, is planning to concentrate all its French powder methionine production at Roches-Roussillon. This project aims to safeguard the competitiveness of Adisseo's methionine activities in Europe by adapting its industrial facilities to an increasingly competitive environment. In this context, it is planned not to restart the powder methionine workshop at the Commentry site, which has already been shut down since October 2022 because of the structural deterioration in market conditions. In its statement, the company emphasized: • Worldwide, methionine production capacity has been growing faster than demand, leading to a mismatch between supply and demand, particularly in Europe, where demand for powdered methionine is falling. • The utilization rate of industrial tools worldwide is set to fall by around 15% between 2023 and 2026, to 80%, compared with almost 95% in 2018. After taking the time to conclude that no option would restore this plant's competitiveness, Adisseo is forced to decide not to restart it. As a result, 47 net jobs are to be cut at the Commentry site, out of a total workforce of 335 (as of December 1, 2023). To provide the best possible support for each employee concerned, an internal redeployment and voluntary redundancy plan would initially be set up, and the measures of a robust job protection plan would be negotiated with the trade unions. Read more>>

NEWS FEED & ADDITIVE MAGAZINE February 2024 15 Globe Buddy introduces new dog food with insect protein Danish pet food company Globe Buddy introduced a super-premium dog food based on a novel and sustainable source of protein: insects. The brand wants to inspire a positive change and help dog owners live greener pet lives. “We have made it easy to feed your furry friend a healthy and tasty diet while doing some good for the planet, simply by reducing the climate impact of dog food,” said Bjarne Gravesen Jensen, CEO and co-founder of Globe Buddy. According to the company's statement, the insect-based dog food Globe Buddy Brown features protein from the black soldier fly larvae, which is good for all dogs, especially those with sensitive digestion or intolerances to traditional meats. It is also a win for the climate. Using insect protein in pet food reduces carbon emissions. The carbon footprint of the ingredients in Globe Buddy's new product is just over half that of the ingredients used in the market's average dog food, according to calculations performed by the consultancy firm Viegand Maagøe on behalf of Globe Buddy. The insect-based product comes with a third-party-verified carbon footprint, something that is still rarely seen in the pet food industry. “While many companies have brought what are claimed to be green pet foods to market, we saw a need among pet parents for increased transparency in the environmental sustainability of their dog’s food. Our brand aims to address this unmet need,” said Bjarne Gravesen Jensen. Read more>> Supplant D Optimizing broiler performance • Improving feed intake. • Better feed conversion. • Reduced mortality. • Higher ROI agrimprove.com M-prove

NEWS 16 FEED & ADDITIVE MAGAZINE February 2024 The proposed combination of the legacy companies Novozymes and Chr. Hansen has been successfully completed, establishing the company Novonesis. The company stated that Novonesis is a world-leading biosolutions partner for better business, healthier lives, and a healthier planet. The combined company brings together 10,000 people worldwide and an expertise that spans more than 30 different industries. Novonesis is already assisting companies around the world in meeting both business needs and the needs of the planet. Ester Baiget, President and CEO of Novonesis, says: "We have successfully combined Novozymes and Chr. Hansen, and today we come together as one leading global biosolutions partner. Novonesis combines our joint strengths and the wonders of biology, and we are set to lead a new era of biosolutions. We will innovate and develop transformative biosolutions that improve the way we all produce, consume, and live. And we have gathered the brightest minds, and together with my 10,000 colleagues, we will unlock the limitless potential of biosolutions." "I am pleased to witness the realization that Novozymes and Chr. Hansen’s combination creates a true global biosolutions leader. We will continue to create powerful biosolutions for our customers and partners based on our more than 100 years of innovation and application expertise. Together, we will serve as a growth partner to our customers, a value creator to our shareholders, and a company that has a significant, positive impact on society and the planet. Novonesis builds on a shared heritage of sustainability leadership and will keep leading the way,” adds Cees de Jong, Chairman of Novonesis. Read more>> Novonesis becomes a leading global biosolutions partner Focusing on developing and delivering innovative programmes to efficiently produce safer food, Anitox focused on antibiotic removal and productive poultry production and launched a new feed mill biosecurity digital application during IPPE 2024. Additionally, Dr. Enrique Montiel, Anitox Global Director of Nutrition and Live Production, presented during the IPPE TechTalk series on “The Challenge of Removing Antibiotics: Innovative Interventions for Productive Poultry Production”. “The removal of antibiotics from food-producing animals has called for substantial changes, leading to a transformation in key aspects of poultry production. The poultry industry is challenged with finding new and improved management practices and ways to prevent disease while Anitox focuses on antibiotic removal and launches new biosecurity app at IPPE

NEWS FEED & ADDITIVE MAGAZINE February 2024 17 Safer ingredients for safer feed. Saving feed ingredient processors millions in lost productivity also continuing to improve overall performance and profitability. The continued development of chemical, biological, and physical interventions for disease prevention from placement to processing has aided in the shift to antibiotic-free production. A greater understanding of the importance of the microbiome on intestinal health, productivity, immune responses, and the control of pathogens of avian and human importance has led to targeted intervention strategies. Feed not only impacts the microbiome due to microbial loads but also serves as a delivery system for interventions during growth,” says Dr. Montiel. Referring to the free feed mill biosecurity audit application, Dr. Montiel said: "We continue to invest in research uncovering how these alternatives support poultry performance. However, the work doesn’t stop there. Managing microbial risk and safeguarding the food chain require multiple points of intervention. In October 2023, our work led to the launch of an inaugural, free Feed Mill Biosecurity Audit app specially designed to help mill managers identify areas of concern in feed mills, implement good manufacturing practices, and adhere to regulatory biosecurity requirements.” Anitox notices that the app is available for free on iOs and Google Play Stores, and the data collected is protected and private, with Anitox relinquishing the right to track user-given audit data. Dr. Montiel explained: “Creating meaningful biosecurity programmes through auditing feed mills and gathering supporting data can be a tedious, though essential, task. For years, our feed mill technologists have been inspecting facilities with our partners, collecting evidence, and generating reports for regulatory and compliance bodies worldwide. This process has become much easier for our partners to manage with the introduction of the new Feed Mill Biosecurity Audit app.” Read more>>

NEWS 18 FEED & ADDITIVE MAGAZINE February 2024 Athian announced the first sale of verified carbon credits in the groundbreaking livestock carbon insetting marketplace to Dairy Farmers of America (DFA), the largest U.S. milk marketing cooperative. Texas dairy farmer Jasper DeVos utilized Athian’s first accepted protocol to generate carbon credits by reducing enteric methane and improving feed utilization through the use of an innovative feed management product and quantification tool from Elanco Animal Health, resulting in nearly 1,150 metric tons of carbon dioxide equivalent (CO2e) reduction. If the entire U.S. dairy industry leveraged this same intervention, it could avoid 4.7 million metric tonnes of CO2e emissions annually from enteric, feed, and manure emissions, accelerating the impact animal agriculture has on being part of the climate solution. DFA is proud to lead the way as the first U.S. dairy cooperative to establish a science-based target (SBT) with the goal of reducing greenhouse gas emissions across the supply chain by 30% by 2030. As part of an industry-wide collaboration on environmental sustainability through the Innovation Centre for U.S. Dairy, DFA is a key contributor to the dairy industry’s commitment to become greenhouse gas neutral or better by 2050. "Dairy farmers raise their families and their herds on the same land. They have always been the true stewards of the land, the air, and the water and, as a result, have been consistently reducing their carbon footprint, year in and year out, decade after decade. However, the necessary systems have not been in place to quantify their tremendous environmental progress in a manner that would compensate for the ongoing investments they have made over generations. The marketplace can now finally allow farmers to realise financial benefits from their initiatives,” said Dennis Rodenbaugh, President and CEO of Dairy Farmers of America (DFA). Read more>> Dairy Farmers of America purchases first verified carbon credits Dr. Chet Wiernusz from Elanco Animal Health Incorporated, presented data showing a direct correlation between the use of chlorine dioxide in drinking water and poultry health during one of this year’s TECHTalks at IPPE 2024. Specifically, producers learned about the benefits of chlorine dioxide, including a decreased pathogen load, improved live performance in poultry and benefits in gut health, compared to producers who use alternate water treatment solutions or leave water untreated. The insights shared by Dr. Wiernusz are based on recent studies and years of experience working with chlorine dioxide. “Water is one of the most important nutrients for poultry. Although the need to provide birds with access to water is understood, providing birds with access to high-quality water is less understood because it is difficult to quantify,” said Dr. Chet Wiernusz, technical advisor for Elanco Animal Health. “A recent study of broiler and turkey data suggest that bird body weight and feed conversion were consistently improved after water treatment with Chlorine Dioxide.” Read more>> Elanco present data on use of chlorine dioxide in drinking water

NEWS FEED & ADDITIVE MAGAZINE February 2024 19 Amlan® International, the animal health business of Oil-Dri® Corporation of America, showcased its commitment to advancing animal health and feed technology through multiple onsite presentations at the International Production and Processing Expo (IPPE). The Amlan team engaged with an international audience of animal production professionals, sharing comprehensive insights into its range of mineral based feed additives with attendees, media, and fellow exhibitors. NeutraPath®, natural pathogen control, was featured in the expo’s new product showcase and was the primary focus of Dr. Aldo Rossi’s seminar, Mitigate Performance Challenges to Drive Profits Naturally. The seminar focused on natural solutions for gut health. On the latest NeutraPath research shared at the expo, Dr. Wade Robey, President of Amlan International, commented: “This innovative product has a synergistic formula with multiple modes of action that is shown to provide equivalent performance to industry standard antibiotics. The natural feed additive has been proven to reduce pathogenic bacterial load and colonization, improve performance of pathogen-challenged poultry and livestock, and reduce mortality.” Attendees learned more about the latest in protein and feed technology throughout the IPPE week with Amlan’s sponsored events. “Presentations at this scale provide an invaluable platform for us to address and learn about industry-specific technical challenges,” said Dr. Aldo Rossi, Vice President, Innovation and Technical Service, Amlan International. “We take pride in our safe, effective, and consistent mineral feed additives for poultry and livestock. Our goal is to help our partners efficiently elevate the standard of producing animal protein and we are excited about sharing these innovative solutions with global producers.” Read more>> Amlan showcases natural mineral technology at IPPE Dog and cat food manufacturer United Petfood announced that a share purchase agreement has been signed for the acquisition of Vital Petfood Group in Ølgod, Denmark. The takeover of the first plant in the Nordics is part of the planned growth strategy of United Petfood, according to the company. "Thanks to the acquisition of Vital Petfood Group, our network of production sites will be able to offer flexibility and bring our production more and more close to our customers also in the Nordics,” comments the management of United Petfood. “There has been a lot of consolidation within the pet food production industry during the recent years. We wanted to find a new owner to continue developing our pet food production in the long run. This divestment enables us to focus and further strengthen our branded businesses within Nordic Pet Care Group," said Mika Holappa, CEO of Nordic Pet Care Group. He added: "Being one of the leading European producers of pet food, United Petfood was an obvious choice of partner and new owner of VPG. We are confident that VPG will benefit from United Petfood’s European customer footprint as well as extensive experience with operating multiple pet food production sites. Furthermore, we expect United Petfood to be able to utilise VPG’s strong position in the Nordics and the Danish market, in particular." Read more>> United Petfood plans to acquire Vital Petfood Group

NEWS 20 FEED & ADDITIVE MAGAZINE February 2024 USE OF ADVANCED TECHNOLOGIES AND FEED ADDITIVES IN CONNECTING GUT MICROBIOME MATURATION TO BROILER PERFORMANCE In the dynamic landscape of global meat production, poultry stands as a frontrunner, poised to lead by a staggering 59% in the coming decade, according to forecasts by OECD/FAO (2022). Yet, the challenge lies not just in meeting the burgeoning consumer demand but in doing so sustainably. The looming imperative is to optimize production while mitigating reliance on antibiotics and chemicals, ensuring the resilience of our food systems. At the heart of sustainable poultry production lies the intricate ecosystem of the gut microbiome, a complex interplay of bacteria essential for gut health and production efficiency in broilers. With each gram of intestinal digesta teeming with 10^9 to 10^11 bacteria, navigating this microbial landscape presents a formidable task. The quest for sustainable solutions demands a deep understanding of the gut microbiome's nuances and its profound impact on poultry health and performance. Enter the concept of gut microbiome maturation—a pivotal phenomenon that charts the course of broiler health and productivity. Through meticulous analysis aided by cutting-edge technologies like the Galleon™ Microbiome Intelligence, researchers unravel the maturation trajectory of the broiler gut microbiome. From lactate producers laying the foundation to butyric acid virtuosos fortifying gut integrity, the journey towards a resilient microbiota unfolds. Critical insights emerge, revealing that high-performing flocks boast a more mature microbiome early on, enhancing their resilience to environmental stressors and bolstering nutrient utilization. In contrast, low-performing counterparts grapple with imbalances, paving the way for opportunistic harmful bacteria and compromised production efficiency. In the quest to shape a favorable microbiome landscape, dietary interventions emerge as potent tools. Postbiotics, hailed as inanimate microorganisms or their components conferring health benefits, emerge as game-changers. Meta-analyses underscore the pivotal role of postbiotics in nurturing lactate producers, orchestrating an early microbiome maturation, and paving the way for robust gut health. But the quest for optimal microbiome modulation doesn't end there. Enter the synergy between postbiotics and essential oil compounds—a symbiotic alliance that amplifies performance benefits in broilers. Through a symphony of mechanisms, this novel blend propels butyrate producers to the forefront while quelling the rise of harmful pathogens, culminating in superior growth and feed conversion ratios. The journey towards sustainable poultry production is intrinsically intertwined with unraveling the mysteries of the gut microbiome. By leveraging advanced tools and technologies, we unlock the potential to optimize animal health, enhance performance, and fortify preharvest food safety. As we decode the intricate dance of bacteria within the broiler gut, we pave the way for tailored interventions, ushering in a new era of sustainable poultry production—one microbiome at a time. Read More>> SPECIAL NEWS