Feed & Additive Magazine Issue 35 December 2023

December 2023 Year: 3 Issue: 35 Feed Additive INTERNATIONAL MAGAZINE FOR ANIMAL FEED & ADDITIVES INDUSTRY Julia Laurain, Nor-Feed The use of a citrus extract in sustainable animal production Yann Fournis, Cargill We have tools necessary to help poultry producers thrive Guillaume Maio, ADM Unleashing the possibilities of specialty ingredients for pet nutrition www.feedandadditive.com Role of Feed Additives in Sustainable Animal Production Natural and Sustainable Ingredients in Pet Foods

Animal protein production plays a critical role for nutrition and food security worldwide. However, this form of production faces significant challenges in terms of environmental sustainability. Conventional animal protein production can cause serious environmental problems such as water and land use, greenhouse gas emissions and biodiversity loss. Therefore, sustainability in animal protein production is an important factor that will shape the future of this sector. Sustainability involves reducing environmental impacts as well as improving animal welfare and enhancing food safety. This can be achieved through strategies such as more efficient feed use, waste reduction and the use of renewable energy sources. It is known that alternative feed ingredients and feed additives have an important role, especially in increasing feed efficiency and reducing the environmental footprint of both livestock and feed, and this role will gradually increase in the future. Similarly, in the pet food industry, sustainability and natural ingredients are among the topics discussed intensively, driven by demand from pet parents. Parents take a close interest in the health and welfare of their pets as they see them as members of the family. Health and welfare are primarily linked to nutritional quality. In addition, parents' awareness and selectivity regarding environmental impact is increasing day by day. Therefore, the use of natural and sustainable ingredients in pet food is important for both the health of pets and the protection of the environment. In this latest issue of 2023, where we focus on these two interrelated topics, we discussed how sustainability can be a growth and differentiation driver for the animal nutrition industry, and what are some of the best practices and examples of leading companies in this field. We hope you will find informative and useful. Enjoy your reading! See you again in the first issue of the new year! Wishing you a happy holiday season and wonderful New Year! Publisher Muhammed Akatay [email protected] Responsible Manager Özlem Akatay [email protected] Editor-in-Chief Derya Yıldız [email protected] Editors Bahadır Büyükkılıç Burak Varol [email protected] Design Alper Kandemir [email protected] Web Design Caner Cem Pulat [email protected] Proofreading Lisa Atakul [email protected] Circulation and Data Responsible Amine Şengün [email protected] Ataturk St. Metropol Istanbul Ste. Block C1, No:376 Atasehir, Istanbul/TURKEY Phone: +90 850 220 5064 E-Mail: [email protected] Web: www.feedandadditive.com Publication Type: Periodic (Monthly) EDITOR Sustainability and Feed Additives: The Future of Animal Protein Production Derya YILDIZ © Three Plus Media | All rights reserved. Reproduction, in whole or in part, is prohibited without the written permission of the publisher. *DISCLAIMER: All views and ideas expressed in articles published in the magazine reflect the point of views of the author(s), not that of the Editor-in-Chief, Editors, Editorial Board or Publisher of Feed & Additive Magazine. The Editor-in-Chief, Editors, Editorial Board and Publisher assume no responsibility or liability in such cases. The publisher does not give any warranty and representation to the accuracy or completeness of the contents and data published in the magazine. All responsibility of the contents, articles and information published in the magazine belongs to the authors. The publisher and the authors cannot be held responsible for any damages resulting from the use of the whole or part of the content of the magazine. feedandadditive

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CON T E N T S 22 ISSUE FOCUS 27 THE ROLE IMPEXTRACO® TAKES TO SUPPORT ITS CUSTOMERS IN A SUSTAINABLE ANIMAL PRODUCTION Léon Vanden Avenne, Impextraco 24 SUSTAINABLE FEEDING: PLANT-BASED MAGIC AGAINST ENDOTOXINS Muhammad Umar & Dr. Bernhard Eckel, Dr. Eckel Animal Nutrition 46 DOES PALM OIL HAVE A PLACE IN SUSTAINABLE ANIMAL PRODUCTION? Pablo Arranz, Golden Agri-Resources 42 THE IMPACT OF TRACE MINERALS ON FEED AND PREMIX SUSTAINABILITY Kevin Perryman, Selko Feed Additives 44 THE USE OF A CITRUS EXTRACT IN SUSTAINABLE ANIMAL PRODUCTION Julia Laurain, Nor-Feed 32 SUSTAINABILITY MEETS FEED ADDITIVES Sandra Chamusco & Elisabeth Rohrer, Cargill 36 NEW PATHWAYS IN SUSTAINABLE ANIMAL PROTEIN David Nickell, dsm-firmenich 40 HOW TO MAKE SUSTAINABLE PIG PRODUCTION MORE PROFITABLE? Anne-Laure Ledoux, Agrimprove ROLE OF FEED ADDITIVES IN SUSTAINABLE ANIMAL PRODUCTION INTERVIEW 52 EUROPEAN PET FOOD INDUSTRY CONTINUES TO GROW Alice Tempel Costa, FEDIAF 48 "WE HAVE TOOLS NECESSARY TO HELP POULTRY PRODUCERS THRIVE” Yann Fournis, Cargill

CON T E N T S SPECIAL STORY Adisseo publishes handbook on liquid additive application in feed 8 Trouw Nutrition expands its research campus for sustainable dairy farming 10 Purina awards research grants to better understand the human-pet bond 92 Alltech ONE World Tour welcomes international agriculture leaders to Dubai 12 Nor-Feed unveils LCA of citrus extract feed additive 18 MicroHarvest launches pilot plant to produce single-cell protein samples 88 NEWS REPORTS GLOBAL ALTERNATIVE PROTEINS MARKET 78 Natural and Sustainable Ingredients in Pet Foods 58 FUNCTIONAL INGREDIENTS SUPPORT PET WEIGHT MANAGEMENT Dr Maygane Ronsmans, BENEO 61 UNLEASHING THE POSSIBILITIES OF SPECIALTY INGREDIENTS FOR PET NUTRITION Guillaume Maio, ADM 68 BOOSTING MILK PRODUCTION WITH CHOLINE SUPPLEMENTATION DURING THE TRANSITION PERIOD Kari Estes, Balchem Animal Nutrition and Health 70 TRANSFORMING POULTRY PRODUCTION: EXCLUSIVE INNOVATION FOR SALMONELLA CONTROL Dr Stéphanie Ladirat, NUQO 73 NANOTECHNOLOGY AS A TOOL TO UTILIZE THE NUTRACEUTICALS IN AQUAFEED Thangaraju Thiruvasagam & Dr. Amit Ranjan, TNJFU ARTICLES 54 BOTANICAL EXTRACTS: THE NEXT GENERATION OF ANTIOXIDANTS Cristina Murcia García, Kemin Nutrisurance EMEA 64 A ROADMAP TO A MORE SUSTAINABLE PET FOOD SECTOR Marcie J. Campion, Cargill

NEWS 6 FEED & ADDITIVE MAGAZINE December 2023 dsm-firmenich, the leading innovator in health, nutrition, and beauty, and Sustained, a SaaS sustainability company, announced their partnership to enable customers to report the farm-to-fork environmental footprint of food products containing animal proteins including eggs, meat, milk and fish. This agreement, the first of its kind, allows farmers, processors, food manufacturers and retail brand owners to manage and communicate the sustainability of food production by leveraging dsm-firmenich’s Sustell™ service for capturing farm-level specific emissions data and Sustained’s platform to deliver product-level environmental life cycle assessments of consumer food products at scale. David Nickell, Vice President of Sustainability & Business Solutions at dsm-firmenich Animal Nutrition & Health, said: “Connecting Sustell™ to the broader data ecosystem through multiple partnerships is key to unlocking the value of sustainability for our customers and the value chain. Our partnership with Sustained underlines our commitment to making this possible. We believe that an accurate, scalable and credible assessment of a product's environmental impact from farm to fork will help inform consumer choice and drive more sustainable food production. The combined platforms empower businesses to set achievable reduction targets, guide new product development, facilitate eco-labelling, and ensure compliance with evolving regulations based on real production data.” Carl Olivier, co-founder & CEO at Sustained, added: “Until recently, full Life Cycle Assessment (LCA) for farm and food products has been an expensive, manual effort that exceeded the resource capacity of firms with hundreds or thousands of SKUs. With this partnership we make data management from farm to fork easier to manage and maintain at scale, bringing greater transparency that empowers more sustainable food production and consumption.” Read more>> dsm-firmenich and Sustained join forces for environmental reporting of animal food products Central Garden & Pet acquires pet treat company TDBBS Central Garden & Pet, a market leader in the pet and garden industries, announced that it acquired TDBBS, LLC, from Bregal Partners. Based in Richmond, VA, TDBBS is a provider of premium natural dog chews and treats. The addition of TDBBS will expand Central’s portfolio with bully and collagen sticks, bone, and jerky and further strengthen Central’s eCommerce and digital capabilities, explained the company. “We are excited to welcome the TDBBS team into the Central Garden & Pet organisation,” said Beth Springer, interim CEO of Central. “Our Central to Home strategy is focused on building further scale in our two industries and growing leading brands consumers love. Adding TDBBS’s established brands and digital capabilities solidifies our position in the large and growing dog treats and chews category and will strengthen our footprint with key customers.” “For over 15 years, TDBBS has been proud to offer the widest selection of high-quality natural dog treats and chews. We believe pets are family, and they deserve quality ingredients just like us. We are excited for this next chapter in our business as part of Central Garden & Pet,” said Tom Goundrey, CEO of TDBBS. Read more>>

NEWS FEED & ADDITIVE MAGAZINE December 2023 7 Skretting, one of the global leaders in providing innovative and sustainable nutritional solutions for the aquaculture industry, announced a new partnership with Zooca Calanus, one of the leading innovators in sustainable marine ingredients. This partnership aims to provide innovative and sustainable nutritional solutions by leveraging Zooca Calanus' expertise in harvesting and processing Calanus finmarchicus, a tiny marine copepod rich in essential nutrients. With over 10 years of prior collaboration, Skretting and Zooca Calanus will now work together to develop high-quality, nutritionally optimised feeds using Calanus-based ingredients and whole fresh canned copepods. These solutions will enhance the health and growth of farmed aquatic species while promoting sustainable practices within the aquaculture sector. By harnessing the natural benefits of Calanus finmarchicus, both companies are committed to advancing the performance of the target species sustainably and responsibly. "We are excited to embark on this journey with Zooca Calanus," said Hassan Skøien, Shrimp Innovation Director at Skretting. "This partnership represents a significant step forward in our mission to provide innovative and sustainable solutions to the aquaculture industry. By combining Skretting's expertise in aquafeed formulation with Zooca Calanus' unique marine ingredients, we aim to set new standards for nutrition, health, and sustainability in aquaculture." “Calanus is an abundant resource. Incorporating it into our diets allows us to diversify marine ingredients and provides employment opportunities for local fishing communities during their low season,” said Eamonn O’Brien, Global Product Manager of LifeStart at Skretting. Read more>> The International Production & Processing Expo (IPPE), sponsored by the U.S. Poultry & Egg Association (USPOULTRY), the American Feed Industry Association (AFIA), and the Meat Institute, will be held at the Georgia World Congress Center from 30 January to 1 February 2024 with the largest exhibit space ever. IPPE show organizers explained that IPPE 2024 has surpassed 600,800 square feet of exhibit space and has secured more than 1,295 exhibitors with two and a half months remaining until the show opens. “We are really pleased with the expanded show floor square footage and the level of exhibitor participation. This is going to be an exciting show that you will not want to miss,” stated IPPE show organizers. The 2024 IPPE will provide attendees with a full week of education programs, innovative technology, engaging activities on the show floor, and enhanced networking opportunities with industry leaders from the animal food, meat, poultry, and egg industries. The vast trade show floor will showcase the latest technology, equipment, and services used in the production and processing of animal food, meat, poultry, and egg products. Combining the expertise from AFIA, USPOULTRY, and the Meat Institute, IPPE will also feature more than 80 hours of dynamic education sessions focused on current industry issues. Read more>> Skretting partners with Zooca Calanus to develop innovative nutritional solutions IPPE Trade Show to open with largest exhibit space ever

NEWS 8 FEED & ADDITIVE MAGAZINE December 2023 Adisseo, one of the world leaders in animal nutrition, announced the publication of a handbook on the liquid additive application in feed. According to the company's statement, liquid additives and supplements, or liquid micro-ingredients, are added at levels of between 0.1 to 5 kg/metric ton, depending on the product. The common stages for inclusion are with raw materials at reception or, in the majority of cases with feed, either in the mixing or post-pelleting phases. In the handbook, the company first provides an overview of additives that can be used in liquid form, when they can be added during the process, and the characteristics to factor in for the right application. The handbook provides a practical guide to gain insights on good practices for equipment design, implementation, and monitoring and reviews all the key steps in applying a liquid additive. Once this is completed, the quality of the application needs to be controlled. Other aspects such as proper sampling, analysis and calculation methods, and assessment of the relevant parameters are also covered in the handbook. The company stated: "We sincerely hope that it will be a helpful guide and provide valuable information to plant managers, quality managers, maintenance managers, process operators, nutritionists, researchers, and equipment developers who would like to know more about the application of liquid additives." Read more>> Adisseo publishes handbook on liquid additive application in feed Novus made a new home for itself in Brazil. The intelligent nutrition company moved its Latin America headquarters in October to better meet the needs of local representatives and customers in the poultry and swine industries. “Our team in Brazil and throughout Latin America has called the Sky Towers in Indaiatuba our home base since 2018,” said Alessandro Lima, senior regional business manager for Novus in Brazil. “We were fortunate to find a space in our current building that better suits our needs and allows us to continue serving our customers in a permanent environment.” The purpose of the move is to support the hybrid work model that the company embraced during the height of the pandemic, allowing Novus colleagues greater autonomy to do their best work from wherever they are most effective. This change also supports Novus’ new branding initiative, which launched in June. The company updated its mission, vision, and values with an emphasis on customer focus, celebrating teamwork, and empowering employees to embrace agility and innovation. The new location has hot desks, meeting spaces, areas for collaboration, and flexible work areas that are available 24 hours a day, seven days a week. Three conference rooms provide plenty of space for Novus to meet with customers about their poultry or swine operations. “We investigated moving to another area of Brazil but decided Indaiatuba, with its restaurants and hotels, and the proximity to Campinas with its many attractions, Viracopos International Airport, and the city of São Paulo, really has all the amenities we want for our employees and our customers,” said Augusto Araujo, Novus senior procurement and facilities coordinator for Latin America. Read more>> Novus moves its Latin America headquarters to better serve

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NEWS 10 FEED & ADDITIVE MAGAZINE December 2023 FAO opens Global Forum for Animal Feed and Feed Regulators Scores of international experts, including government officials, researchers and industry leaders from several continents, gathered at the Food and Agriculture Organization of the United Nations (FAO) headquarters in Rome for the Global Forum for Animal Feed and Feed Regulators. The Forum focused on a sector that generates more than $400 billion in annual commercial turnover and produces more than one billion tons of livestock feed, a key input for animal health, human nutrition and environmental sustainability. The livestock sector must transform along with other elements of global agrifood systems to be more efficient, more inclusive, more resilient, and more sustainable, to the benefit of people and the planet, FAO Director-General QU Dongyu said in opening remarks at the Forum. A critical pathway is ensuring the availability, accessibility, quality and safety of animal feed, which will require concrete actions ranging from the management and restoration of grasslands and pastures to the production of fodder and feed ingredients Nutreco's animal nutrition company, Trouw Nutrition, one of the leaders in functional and nutritional solutions for sustainable livestock farming, reached a new milestone in its journey to help farmers operate more efficiently and sustainably. The company has announced the expansion of its research campus to include a company-owned dairy facility in Sint Antonis, the Netherlands. The company states that this addition clearly underscores the company's commitment to advancing sustainable dairy farming practices. “Our ambition is to be recognised as the reference for scientific leadership in the animal nutrition industry by delivering high-quality results to the standard of peer review for the development of functional and nutritional customer-based solutions for sustainable farming,” said Dr. John Doelman, R&D Director of Trouw Nutrition. The newly acquired facility, strategically located beside Trouw Nutrition's existing research hubs dedicated to beef cattle, calves, and swine, will deliver value-adding and science-driven solutions for dairy farmers. Its team will focus on developing cutting-edge nutritional knowledge and solutions, utilising proprietary ingredients, and pioneering young animal feed solutions, all of which contribute to dairy production sustainability. Once renovations are completed, the facility is set to exceed prevailing environmental legal standards, including Nutreco’s Health, Safety, and Environment benchmarks. Within a year, it will be home to 100 lactating dairy cows, serving as a practical demonstration of sustainable dairy production in the Netherlands, a region renowned for its stringent sustainability legislation. “We’re thrilled to announce this milestone,” said Javier Martín-Tereso, Ruminants Research Director. “To us, this isn't just a new research facility; it's a symbol of the commitment we make to farmers, consumers, and the planet that we will continue to drive forward more sustainable farming practices and help transform our industry.” Read more>> Trouw Nutrition expands its research campus for sustainable dairy farming

NEWS FEED & ADDITIVE MAGAZINE December 2023 11 and the processing and use of compound feed, all of which will require appropriate policies and regulations, he added. “Feeding animals well will feed the world better,” Qu said. The Global Forum is organized to offer an inclusive discussion platform for national and regional feed regulatory competent authorities, FAO Members, private sector, researchers, development agencies, financial institutions and civil society. Case studies offered all participants the opportunity to explore cutting-edge innovations and strategies to enhance the production of high quality, safe and environmentally responsible animal feed. Executives from trade groups such as the International Feed Industry Federation (IFIF), scientists and policy experts from Brazil, Ghana, Mexico, Morocco, the Netherlands, Nigeria, Uganda and the United States of America among other countries, and representatives of regional pastoralist networks from around Africa, spoke on the Global Forum. They are addressed topics ranging from ensuring feed availability to developing and implementing related legislation optimizing feed ingredients for desired health, quality and environmental outcomes. FAO experts offered insights into the Organization’s work on the Sustainable Livestock Transformation Initiative, animal nutrition and feed safety, alternative and advanced feed practices to reduce the need of antimicrobials, and normative work on food standards set out in the Codex Alimentarius. Read more>> Gut health is more than a gut instinct. Improving bird productivity through clean feed. Get the study today. www.anitox.com/broiler-performance

NEWS 12 FEED & ADDITIVE MAGAZINE December 2023 The Alltech ONE World Tour (ONE), a series of international events bringing the ideas and inspiration of the annual Alltech ONE Conference to the world, was held on November 27-28 in Dubai, the United Arab Emirates. ONE Dubai welcomed international attendees to explore collaborative solutions to the greatest challenges facing the agri-food industry in the Middle East, Africa, and beyond. For the past 38 years, the Alltech ONE Conference has been held in Lexington, Kentucky, the home of Alltech’s global headquarters. In 2023, however, the company — a global leader in the field of agriculture — is bringing the conference to its partners, customers, suppliers, and friends around the world, providing the opportunity for more people than ever to experience the power of ONE. “As our customers and partners continue to face many challenges and uncertainties, we determined that 2023 would be dedicated to meeting them in their markets,” said Dr. Mark Lyons, president and CEO of Alltech. “This special edition of the ONE endeavours to deliver global expertise on locally relevant issues. In the midst of economic and political uncertainties that fuel regionalization, this ONE reflects the responsibility we have as a global company to be a connector of people and ideas, ever advancing our purpose of Working Together for a Planet of Plenty™.” Alltech ONE Dubai features discussions led by local and international experts about the latest trends in sustainable agricultural, animal nutrition, and business, included presentations from Dr. Lyons; Tara McCarthy, global vice president of ESG at Alltech; Sheikh Dr. Majid Al Qassimi, founding partner at Soma Mater; and Gerald Kiernan, general manager of dairy farms at Emirates Food Industries (EFI). In his opening remarks, Dr. Lyons welcomed delegates to Dubai to discuss agriculture’s role in saving the planet. “Agriculture can transform things in ways that other industries cannot, and we are at the interface of nourishing the present and preserving the future,” he said. “Our belief is that agriculture has the greatest potential to positively influence the future of our planet, provide nutrition for all, help rural communities thrive, and replenish our planet’s resources.” Alltech recently released the results of the Alltech Sustainability Insights report, and McCarthy discussed those findings in further detail during her presentation. Read more>> Alltech ONE World Tour welcomes international agriculture leaders to Dubai COFCO International, a global agriculture trading house, passed an independent benchmarking process and will be able to offer deforestation and conversion-free soy under the European feed industry’s requirements, as outlined in the 2023 FEFAC Soy Sourcing Guidelines. The process was enabled by FEFAC, the European Feed Manufacturers' Federation, the creator of the benchmarking programme, and run by the International Trade Centre (ITC), the United Nations, and the World Trade Organization’s joint agency. The COFCO International Responsible Agriculture Standard is a voluntary certification programme for agricultural producers and another chain of custody supplier that promotes conservation and the mainstreaming of sustainable agriculture in supply chains. Read more>> COFCO International to offer deforestation and conversion-free soy

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NEWS 14 FEED & ADDITIVE MAGAZINE December 2023 Lithuanian insect producer Divaks selected the Swiss technology group Bühler to build its first commercial-scale yellow mealworm plant. Scheduled to go into operation in 2025, the plant will produce up to 15,000 tonnes of sustainable insect-derived products annually. Bühler will be responsible for planning and executing the plant as well as providing solutions for the entire supply chain. Following the establishment of its pilot facility in May 2022, Divaks has now taken a major step towards its first industrial-scale yellow mealworm plant. Divaks’ site, which is located in Lithuania’s Marijampolė Free Economic Zone, spans an area of 10,000 square meters. Encouraged by the opportunities in this market, the company expects to double its production in the new facility by 2030. In the new plant, Divaks will produce yellow mealworm (scientifically known as Tenebrio molitor), which is an environmentally friendly, nutritious protein source that can be used in applications including meat alternatives, sports nutrition, snacks, and confectionery as well as premium pet food. The residue from mealworm production (or insect frass) will be utilized as organic fertilizer, as it contributes to healthier soils, fostering a circular economy approach. Divaks has selected Bühler as the technology provider for the plant. Bühler will be responsible for all process technology, which will include feedstock preparation to provide safe, palatable, and nourishing feed to the larvae and a fully automated larvae growth system with sophisticated climate control. Furthermore, Bühler will provide the processing line to transform the harvested larvae into textured insect proteins (TIP), insect protein concentrates (IPC), and other specialized food ingredients. Read more>> Divaks agrees with Bühler to build its first industrial-scale yellow mealworm plant As global leaders gather for COP28 in Dubai, a new analysis of emissions data from 20 of the largest listed meat and dairy firms showed that disclosed emissions are still rising year-on-year. Livestock is estimated to be responsible for around 14.5% of global greenhouse gas emissions. The analysis from the $70 trillion-backed FAIRR investor network showed absolute emissions disclosed by 20 of the world’s largest (by value) meat and dairy producers rose 3.28% between 2022 and 2023. This group includes firms like Hormel Foods (US) and New Hope Liuhe (China), suppliers to household names such as Walmart and McDonald’s, respectively. According to the the FAIRR Initiative's statement, some of the 20 firms saw disclosed emissions fall this year, including Tyson Foods (US) and Danone (FR), but progress was negated by rises from other meat and dairy giants. The analysis of the 20 firms shows varying levels of climate commitment and disclosure. In total, 4 of the 20 firms have set net zero targets approved by the Science-Based Targets initiative (SBTi).- On disclosure, 40% of the 20 companies (8 firms) now publicly report Scope 3 emissions (i.e., emissions from the supply chain such as those from animal feed production), with US-operating Tyson Foods and WH Group (owners of Smithfield Foods) disclosing all scopes for the first time this year. The data comes from the release of the sixth annuMeat and dairy giants fail to reduce emissions

NEWS FEED & ADDITIVE MAGAZINE December 2023 15 al Coller FAIRR Protein Producer Index (the Index), which assesses a total of 60 publicly listed animal protein producers worth a combined $364 billion (as of March 1st, 2023) against ten environmental, social, and governance (ESG)-related factors. “The failure of leading meat and dairy companies to reduce emissions underlines the urgent need for more policy focus on the food and agriculture sector. Food system emissions deserve a place at the top of the table, alongside energy and transport, as they represent an estimated third of greenhouse gas emissions and 40% of methane. Investors hope the first-ever publication of a food and agriculture roadmap at COP28 this month will catalyse the transition to 1.5 degrees and a more sustainable food system,” said Jeremy Coller, Chair and Founder of the FAIRR. “What you can measure, you can manage, so investors will welcome the increased disclosure of Scope 3 emissions by the meat and dairy sector. The FAIRR Protein Producer Index highlights the ESG risks and opportunities in the global food system, enabling investors to engage their portfolio companies in more meaningful conversations, underpinned by data.” Read more>> F3 selects finalists to compete in Krill Replacement Challenge The F3 - Future of Fish Feed selected 10 companies to compete in the F3 Krill Replacement Challenge, a contest designed to spark innovation for alternatives to krill in aquaculture feed. The companies’ products will compete in a head-to-head competition —against each other and krill and fishmeal controls— in a 12-week feed trial on Atlantic salmon, a widely consumed fish that is known by farmers to be finicky eaters. The company with the krill replacement product that results in the best growth, feed consumption, and survival will be awarded a $100,000 grand prize. The F3 Krill Replacement Challenge finalists and their products are: U.S.-based APC LLC (spraydried plasma), Brazil-based BRF Ingredients (chicken hydrolysate), China-based Calysseo (single-cell protein), Finland-based eniferBio (fungus), Singapore-based Entobel (black soldier fly), Netherlands-based Orffa Additives (amino-acid extract), France-based Phileo by Lesaffre (yeast extract), Netherlands-based Protix (black soldier fly), India-based Shaivaa Algaetech (algae), and Germany-based Symrise (protein hydrolysate). “It wasn’t an easy decision to select these finalists out of the 40 great krill replacement products we received,” said F3 Judge Kevin Fitzsimmons, a professor of environmental science at the University of Arizona. “Ultimately, we are happy with the diversity of products and companies that are moving to the next phase of the competition.” The companies advancing to the trial phase of the contest, which is expected to begin in March 2024, were selected from a pool of forty companies from across the world that registered for the F3 Krill Replacement Challenge, the fourth aquaculture feed contest hosted by the F3 - Future of Fish Feed initiative. Testing was performed to confirm all products being used in the trial are free of marine ingredients. Read more>>

NEWS 16 FEED & ADDITIVE MAGAZINE December 2023 Food security and climate change are interlinked and global agrifood systems are the climate solution, the Director-General of the Food and Agriculture Organization of the United Nations (FAO), QU Dongyu, told Heads of State and Government reunited at the World Climate Action Summit in Dubai, United Arab Emirates (UAE). At the COP28 Presidency’s first Leader’s Event focused specifically on food and agriculture, Qu expressed FAO’s support for the newly launched Emirates Declaration on Sustainable Agriculture, Resilient Food Systems, and Climate Action, already endorsed by 134 countries. “Implementation of the Emirates Declaration guided by the FAO Roadmap for achieving SDG2 while maintaining 1.5 degrees Celsius, are key instruments for achieving the Sustainable Development Goals (SDGs) targets under the Four Betters, leaving no one behind,” he said. The roadmap, to be presented later at COP28, captures the vast contributions that nations can make to building climate resilience, adaptation and mitigation, as well as food security, through solutions that only the agrifood sector offers. The climate crisis is affecting the world’s capacity to produce sufficient food. The various impacts on water, soil, biodiversity, and the frequency of extreme weather events are leading to increased food insecurity by diminishing crop yields, livestock productivity, and the potential of fisheries and aquaculture as food producers. "We have to produce more with less. Agrifood systems must be transformed to be more efficient, more inclusive, more resilient, and more sustainable to effectively contribute to food availability, accessibility, and affordability, and to achieve all the SDGs,” Qu underscored. Read more>> FAO Director-General: Global agrifood systems are climate solution Amlan® International, the animal health business of Oil-Dri® Corporation of America and one of the global leaders in mineral-based feed additives that optimise the intestinal health of poultry and livestock, announced an expansion of its presence in the Southern Vietnam market through a new distribution partnership with Saigon Nutrition Corporation. According to the company's statement, Saigon Nutrition, which is well-established and respected in the region, will manage the distribution of Amlan products for the Southern Region of Vietnam. This partnership will allow for a better alignment of customer needs and industry demands. Saigon Nutrition is now authorised to distribute Calibrin®-Z, Varium®, Calibrin®-A, NeoPrime®, and ConditionAde® products. "Amlan is pleased to have Saigon Nutrition as our trusted distributor in Southern Vietnam. This partnership represents a pivotal moment in our commitment to advancing animal health and sustainability in the region," said Wade Robey, Vice President of Agriculture at Oil-Dri Corporation of America and President of Amlan International. The Southern Region of Vietnam is home to a dynamic livestock and poultry industry, where the demand for advanced solutions is increasing. The company's partnership with Saigon Nutrition positions Amlan to deliver its products to local farmers and producers. Read more>> Amlan expands in Southern Vietnam with new distribution partner

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NEWS 18 FEED & ADDITIVE MAGAZINE December 2023 Athian and Elanco launch carbon marketplace for dairy farmers Athian announced the establishment of the firstof-its-kind voluntary livestock carbon insetting marketplace, with the first accepted protocol aimed at reducing enteric methane emissions and improving feed utilisation by using innovative feed management products from Elanco Animal Health. This new carbon marketplace creates an opportunity for farmers to monetize their greenhouse gas emission reductions. “Athian’s first carbon credits for dairy are an exciting and crucial step as they demonstrate the ability to tangibly quantify and verify greenhouse gas emissions reductions and create monetary value for farmers for their efforts,” said Paul Myer, CEO of Athian. “This marketplace, specifically designed for the animal protein industry, is different than traditional offsetting carbon marketplaces because it keeps the value—economic value as well as positive environmental value—in the animal protein value chain.” “As a co-creator and seed investor in Athian, we’re excited to see the company reach the milestones that will bring new value to farmers and help them advance towards climate-neutral farming,” said Jeff Simmons, President and CEO of Elanco Animal Health. “As a leader in animal health, we’ve focused first on delivering enteric methane reduction solutions to producers. If the entire U.S. dairy industry leveraged this intervention, it would avoid 4.7 million metric tonnes of CO2e emissions annually from enteric, feed, and manure emissions. This is a game changer for value creation throughout the food chain, and it’s just the start. Environmental sustainability needs to be grounded in farmer profitability.” Read more>> Nor-Feed taken one more step towards transparency and sustainability, as it announced the publication of the Life Cycle Assessment (LCA) of its citrus extract feed additive in the scientific journal Animals. According to the company, this contribution illustrates Nor-Feed's comprehensive Corporate Social Responsibility (CSR) strategy. Collaborating with the specialised and independent consultancy firm EVEA, Nor-Feed's LCA delves into the impact of manufacturing, distributing, and utilising the citrus extract feed additive in broiler chicken and swine productions. The environmental performance assessment highlights the benefits of incorporating this innovative feed additive into swine and broiler chicken diets, showcasing its potential to mitigate the environmental impacts associated with meat production. For example, the study reveals that the utilisation of 25kg of the citrus extract feed additive in broiler production leads to a net reduction of 6 tonnes of CO2 emissions. This research, subjected to rigorous scientific peer review, exemplifies Nor-Feed's plant-based feed additives as a dual-force solution: enhancing animal zootechnical performances while simultaneously minimising the environmental footprint of meat production chains. Furthermore, the same methodology has been applied to Nor-Feed’s main products. Detailed Life Cycle Analysis (LCA) data for Nor-Feed's key offerings is now accessible in the comprehensive documentation available on the company website. Read more>> Nor-Feed unveils LCA of citrus extract feed additive

NEWS FEED & ADDITIVE MAGAZINE December 2023 19 The Center for Aquaculture Technologies (CATC), a leader in aquaculture clinical research, announced a significant step forward in its mission to deliver exceptional value and drive industry advancement through a strategic partnership with Prelude. According to the CATC, this collaboration integrates Prelude’s state-of-the-art software solutions into the CATC’s service offerings, underscoring a shared dedication to pioneering developments in the field of aquaculture. "Our alliance with Prelude marks a pivotal expansion of our capabilities," said Dr. Fabio Zanuzzo, Manager of Aquatic Animal Health at The Center for Aquaculture Technologies. "We are not just embracing technological innovation; we are actively deploying it to set new benchmarks in the aquaculture sector. Our clients stand to gain immensely from the heightened efficiency and precision that these advanced tools bring to our already robust research methodologies." CATC has a strong reputation for its exceptional clinical research and laboratory services in the aquaculture industry, offering bespoke solutions to the various industries they work in worldwide. With a commitment to excellence over the last 10 years, they have successfully managed clinical trials, ensuring the delivery of high-quality data and timely results. Prelude is a leader in animal health focused electronic data capture (EDC) systems designed to optimize and streamline clinical research processes. This partnership represents a significant step towards providing a comprehensive suite of services that encompass both clinical research expertise and cutting-edge software solutions. This technology is expected to offer a competitive edge to CATC’s clientele by enhancing data accuracy, expediting timelines, and facilitating smarter, more informed decision-making. Read more>> CATC and Prelude collaborate to set new benchmark in aquaculture sector Jefo Nutrition announces its new organisation in Brazil Jefo Nutrition, one of the specialised companies in intestinal precision nutrition solutions for farm animals, announced its new strategic approach for Brazil. To strengthen its presence in the local market, the company has established its own sales and technical support teams to provide better customer service and counselling. All Jefo products, previously marketed by Safeeds, are now available directly through Jefo Brazil. “This new strategy reaffirms our commitment to offering solutions that address the challenges faced by Brazilian producers. By increasing proximity to customers and ensuring more efficient support and communication, Jefo aims to provide in Brazil the same world-class service for which it’s known globally. It’s all based on our philosophy: Life, made easier,” said Lucas Rodriguez, Director of Jefo Brazil. “At Jefo, in addition to offering a comprehensive range of products, our technical and sales teams are available to provide valuable international insights into animal nutrition, health, performance, and management practices,” said Jean Fontaine, President and Founder of Jefo. Read more>>

NEWS 20 FEED & ADDITIVE MAGAZINE December 2023 Entobel opens largest insect protein production plant in Asia Entobel, one of the global leaders in the production of functional insect protein for animal and plant nutrition, celebrated the opening of its new black soldier fly (BSF) production plant, the largest of its kind in Asia. Entobel’s state-of-the-art facility was constructed in an industry record time of 12 months and is currently the world’s most CAPEX-efficient BSF production facility. The facility features 50 levels of vertical rearing, incorporating automation via robotics, cutting-edge sensors, and data analytics that enhance productivity. Leveraging a US$33 million Series B funding round raised in 2022 and backed by Mekong Capital, Dragon Capital, and The International Finance Corporation (IFC), the Vung Tau facility marks Entobel’s second industrial-scale production facility in Vietnam and will have an annual production capacity of 10,000 MT of insect protein. The facility will serve as an economic and community anchor, creating 150 jobs in manufacturing and operations. “Today marks a major milestone in our journey to transform the insect protein landscape and supply sustainable feed ingredients to the rapidly growing aquaculture and pet food industries,” said Alexandre de Caters and Gaëtan Crielaard, co-founders and co-CEOs of Entobel. Read more>> Kormotech, one of the leading Ukrainian pet food producers, announced plans to expand its manufacturing operations in Kėdainiai, Lithuania. Having significantly exceeded its initial hiring plans in the country, the company is now looking to add another 200 specialists to its Lithuanian team, investing more than €60 million in four production stages that will be put into operation during 2025 – 2028. Kormotech first entered Lithuania in 2020, when it launched its 4500 sq. m. manufacturing facility in the Kėdainiai Free Economic Zone (FEZ). The company had first planned to hire a 70-strong team but soon surpassed the initial plans to employ more than 170 specialists. With the new expansion project, Kormotech will double the current headcount in Kėdainiai, adding 200 jobs in five years. "We consider Lithuania our second home market. While we plan to build new production facilities in Ukraine once the war is over, Lithuania currently serves as our gateway to the world. The plant has proven to be a reliable support system, consistently operating at full capacity and bridging the gaps when our Ukrainian plants experience disruptions. We are committed to expanding our facilities in Lithuania further with the construction of four additional production stages by 2028," said Rostyslav Vovk, CEO and co-owner of Kormotech. “Since the start of our Lithuanian operations, both our production and sales goals have been achieved and exceeded, and we hired twice the number of employees originally planned,” said Andrii Berezyuk, Director of Kormotech UAB. Read more>> Kormotech to expand Lithuanian operations

NEWS FEED & ADDITIVE MAGAZINE December 2023 21 At Phileo, we believe in microorganisms and fermentation technologies to make a difference for a more sustainable future. By mastering microbiota and immunity, we offer our partners beneficial probiotics and functional ingredients to improve animal health and performance through nutrition. Act with nature for animal care. Life science to improve animal health and performance

ISSUE FOCUS 22 FEED & ADDITIVE MAGAZINE December 2023 ROLE OF FEED ADDITIVES IN SUSTAINABLE ANIMAL PRODUCTION

ISSUE FOCUS FEED & ADDITIVE MAGAZINE December 2023 23 Sustainable feeding: Plant-based magic against endotoxins Muhammad Umar & Dr. Bernhard Eckel, Dr. Eckel Sustainability meets feed additives Sandra Chamusco & Elisabeth Rohrer, Cargill Does palm oil have a place in sustainable animal production? Pablo Arranz, Golden Agri-Resources The role Impextraco® takes to support its customers in a sustainable animal production Léon Vanden Avenne, Impextraco How to make sustainable pig production more profitable? Anne-Laure Ledoux, Agrimprove The use of a citrus extract in sustainable animal production Julia Laurain, Nor-Feed The impact of trace minerals on feed and premix sustainability Kevin Perryman, Selko Feed Additives New pathways in sustainable animal protein David Nickell, dsm-firmenich

ISSUE FOCUS 24 FEED & ADDITIVE MAGAZINE December 2023 What are endotoxins and why do they cause so much damage? Endotoxins cause considerable damage in livestock farming every year. Worldwide, the economic damage caused by high levels of endotoxin contamination is estimated at up to 20 billion US dollars. This affects all areas of production, not only dairy cattle and beef cattle farms, but also poultry and pig fattening, egg production and aquaculture. But what are endotoxins and why can they cause such damage? Endotoxins are components of the outer cell membrane of gram-negative bacteria such as Escherichia coli. They are released, among other things, when the bacteria die and decompose. Endotoxins occur naturally in the intestines of both humans and animals, as the microbiota also contains gram-negative bacteria. As long as their concentration does not become too high, the body can cope with them: This is where the liver becomes active with its detoxifying function. However, it becomes critical when the endotoxin level rises too high and the liver can no longer cope. The toxins can then lead to fever, inflammation, diarrhoea, circulatory problems, septic shock or even death. They also hinder the absorption of nutrients in the intestine. Our farm animals are affected by endotoxins to varying degrees: While chickens tolerate slightly higher endotoxin levels and primarPlant-based feed additives are the key element in sustainable livestock production. Why? Because they can be used in a wide range of applications, their use is safe for humans, animals and the environment, they do not promote resistances and no withdrawal periods need to be observed. One area where the benefits of the right additive are particularly evident is endotoxin management. SUSTAINABLE FEEDING: PLANT-BASED MAGIC AGAINST ENDOTOXINS Muhammad Umar Technical Sales Manager Dr. Eckel Animal Nutrition Dr. Bernhard Eckel Vice President Dr. Eckel Animal Nutrition

ISSUE FOCUS FEED & ADDITIVE MAGAZINE December 2023 25 ily suffer from more frequent infections, digestive problems and reduced growth, ruminants and pigs react even at lower levels with claw inflammation, ear or tail necrosis. What are the reasons for high endotoxin levels? Reasons for high endotoxin levels can include stress such as high temperatures, birth or rehousing, but can also be a result of antibiotic treatment following illness or a high proportion of concentrated feed in the animals' diet. As these factors can never be completely ruled out in modern animal husbandry, even under optimal conditions, endotoxins occur even on very well-managed farms. It is often not easy for livestock farmers to recognise endotoxin contamination in their animals. Endotoxin levels cannot be measured on the farm. The harmful effects of toxins can be seen in an increase in infections and diarrhoea, in circulatory disorders and necrosis, in animals suffering from pain, in poor growth and poorer product quality. However, it is often not recognised that the cause of all this is endotoxins. It is also often wrongly assumed that mycotoxin binders can also protect against the consequences of endotoxins. However, this is not correct. Chemically and biologically, the two are completely different, which is why they cannot be used with the same effectiveness for each other. Animal owners face three problems with endotoxins: Their animals are sick and need treatment, their sick animals cannot perform to their full potential – eggs, milk, meat – and also cannot utilise the feed optimally. Endotoxins are therefore a serious health problem for our livestock on the one hand and a considerable waste of resources on the other. Combating endotoxins in livestock is therefore a crucial part of animal-friendly and sustainable food production. How can we protect our animals and business against endotoxin damage? This requires several steps: Firstly, endotoxins must be bound in the intestine and inactivated here so that they can cause as little damage as possible. Secondly, the intestinal barrier and thus the health of the animals must be strengthened. And thirdly, the liver needs to be supported in order to promote detoxification and reduce inflammatory reactions. Anta®Catch is the first product that truly takes a holistic approach and thus promises a comprehensive solution to the endotoxin problem. At the same time, it is the only product to date that has been specifically developed and optimised for binding endotoxins. Anta®Catch consists of purely natural ingredients and is currently distributed in Europe and Asia. Due to its triple mode of action, Anta®Catch effectively diminishes the harmful effects of toxins: it reduces endotoxins in the digestive tract, its prebiotic ingredients protect the intestinal barrier,

ISSUE FOCUS 26 FEED & ADDITIVE MAGAZINE December 2023 and its phytogenic substances counteract excessive inflammatory responses. A recent trial in collaboration with a German university has now demonstrated how this combination of natural ingredients impacts a wellmanaged pig farm in practice. The experiment involved two groups of 130 pigs each. The feed of one group contained no feed additive (control) while that of the other contained Anta®Catch. Feeding with Anta®Catch proceeded in three phases: the Anta®Catch group received 2 kg Anta®Catch/t feed in phase 1, which was then reduced to 1 kg Anta®Catch/t feed in phases 2 and 3. In addition to performance parameters, the numbers of ear and tail necroses, treatments and fatalities, derived from the numbers of sick and dead pigs respectively, were also recorded. The results are impressive! The performance parameters were high in both groups (FCR 1:2.71). In the first fattening phase, when the animals are at particular risk of elevated endotoxin levels due to feed change and other stressors, the animals in the Anta®Catch group were 484 g heavier than those in the control group (day 14: 44.96 kg vs 44.48 kg). In addition, feeding with Anta®Catch significantly reduced the numbers of necroses, treatments and fatalities throughout the trial. In fact, the Anta®Catch group had almost 90 per cent less ear and tail necroses (Figure 1a), almost 60 per cent fewer medical treatments (Figure 1b) and half the number of fatalities (Figure 1c) in comparison with the control group. Safeguarding our animals and ensuring sustainable food production requires a proactive approach. Anta®Catch emerges as a game-changer, offering a holistic solution to combat endotoxins in all species due to its unique triple mode of protection, making it the ideal solution for the harmful effects of endotoxins. By embracing such innovations, we not only protect our livestock but also contribute to a healthier, more efficient, and eco-friendly agricultural future. Figure 1. Effects of feeding with Anta®Catch on necrosis (a), medicinal treatments (b) and fatalities (c) About Muhammad Umar With a degree in veterinary medicine and a master in dairy science, Muhammad Umar has already several years of experience in the field of animal nutrition. His special expertise are ruminants and the use of phytogenic feed additives to improve performance and sustainability. As Technical Sales Manager at Dr. Eckel, Muhammad Umar focusses on supporting the company's customers with the best phytogenic solutions for their needs. About Bernhard Eckel Bernhard Eckel has been with the company from the very beginning. The key figure behind Dr. Eckel’s pioneering feeding solutions, he is responsible for technical sales, product development and animal welfare, and thus plays a major role in the success of the company.

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