ISSUE FOCUS 30 FEED & ADDITIVE MAGAZINE November 2023 reasons, as we will see below, not all butyric-based products offer this response. Due to its specific characteristics, Butirex C4 has a strong response on taste and olfactory memory in the early stages of chick development, enhancing from the first days of life a positive sensory experience that has a great impact on consumption. WHAT IS THE REASON FOR THE INCREASED FEED INTAKE WITH BUTIREX C4? There are two fundamental factors that explain the effect on consumption with the use of Butirex C4: • The high palatability of the product • The increased insulin production at pancreatic level An aromatic substance Regarding the first point, associated with the manufacturing technology, the butyric acid contained in Butirex C4 is an aromatic substance that makes this nutrient an extremely palatable ingredient for all animal species, especially in the first ages of chickens. Glucose metabolism A second aspect that contributes to what we have just mentioned is the capability of Butirex C4 to bind to the butyric acid receptors present in the enterocytes, which will trigger a peripheral signal at pancreatic level that will act on glucose metabolism, stimulating the production of insulin and regulating the increased consumption. In the case of the chick, both actions are especially relevant since, as we have mentioned, this increased consumption will have a great impact on the development of the intestine, increasing the length of the villi, stimulating enzymatic maturation and, more significantly, enhancing the absorption of nutrients and their digestibility. Therefore, the increased intake has a direct impact on ADG and FCR during this period. META-ANALYSIS OF 20 TESTS Not all butyric acid-based products increase consumption: The importance of dosage. In bibliography, it is common to note the absence of effects on consumption with the use of other butyric acid-based products, especially certain fat-protected butyrates and some butyric acid esters. In the first place, the protection mechanism used in these molecules plays a major role in preventing butyric acid from having such a marked effect on the Figure 2. Effects of Butirex C4 on ADG (P<0.001; SEM:0.64) and FCR (P<0.001; SEM:0.26) Meta-analysis of 20 trials
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