SPECIAL STORY FEED & ADDITIVE MAGAZINE September 2023 71 Dr. Eyüp Eren Gültepe, DVM Dr. Gültepe is a veterinarian and animal nutritionist, holding a PhD in the field. He earned both his DVM and PhD degrees from Afyon Kocatepe University, Türkiye, and expanded his expertise as a postdoctoral researcher at Kansas State University, KS, USA. With over a decade of experience as a dedicated university researcher, he now leads innovation projects in ruminant platform at Kemin Europa R&D team. Dr. Gültepe has an academic portfolio more than 30 peer-reviewed publications, including articles, reviews, and book chapters. He has also more than 40 oral/poster presentations and keynote speaks across more than 10 different countries around the world. Dr. Diego Martinez del Olmo, DVM Dr. Martínez del Olmo holds a degree in Veterinary and Research Sufficiency and Advanced Studies from León University. He received his PhD from Complutense University (Madrid) and a master’s degree in Dairy Farm Management from the Autonomous University of Barcelona, and in Strategic Management of Feed Companies from the Open University of Catalonia. He has an MBA from Isabel I University (Burgos). He started his career as a clinical veterinarian and subsequently held various positions in animal feed companies. He is currently the business manager for ruminants at Kemin EMENA. Diego is co-inventor of two European patents and has two published books and several peer-reviewed publications. 5. Graulet, B., Richard, C., Robert, J.C., 2005. Methionine availability in plasma of dairy cows supplemented with methionine hydroxy analog isopropyl ester. J. Dairy Sci. 88, 3640–3649. https://doi. org/10.3168/jds.S0022-0302(05)73049-6 6. Kihal, A., Rodriguez-Prado, M., Calsamiglia, S., 2021. Relative bioavailability of 3 rumen-undegradable methionine sources in dairy cows using the area under the curve technique. JDS Commun. 2, 182– 185. https://doi.org/10.3168/jdsc.2020-0045 7. Lapierre, H., Vázquez-Añón, M., Parker, D., Dubreuil, P., Holtrop, G., Lobley, G.E., 2011. Metabolism of 2-hydroxy-4-(methylthio)butanoate (HMTBA) in lactating dairy cows. J. Dairy Sci. 94, 1526–1535. https://doi.org/10.3168/jds.2010-3914 8. Li, S., Zeng, H., Wang, C., Han, Z., 2023. Effect of Methionine Hydroxy Analog on Hu Sheep Digestibility, Rumen Fermentation, and Rumen Microbial Community In Vitro. Metabolites 13, 169. https://doi.org/10.3390/metabo13020169 9. Li, S., Zeng, H., Wang, C., Han, Z., 2022. Effect of methionine hydroxy analog feed supplements: Significant alteration and enrichment of rumen microbiota and metabolome in Hu sheep. Front. Vet. Sci. 9. https://doi.org/10.3389/fvets.2022.999726 10. Lobley, G.E., Wester, T.J., Holtrop, G., Dibner, J.J., Parker, D.S., Vázquez-Añón, M., 2006. Absorption and digestive tract metabolism of 2-hydroxy-4-methylthiobutanoic acid in lambs. J. Dairy Sci. 89, 3508–3521. https://doi.org/10.3168/jds.S0022-0302(06)72391-8 11. McCollum, M.Q., Vázquez-Añón, M., Dibner, J.J., Webb, K.E., 2000. Absorption of 2-hydroxy-4-(methylthio)butanoic acid by isolated sheep ruminal and omasal epithelia. J. Anim. Sci. 78, 1078. https://doi.org/10.2527/2000.7841078x 12. Noftsger, S., St-Pierre, N.R., Sylvester, J.T., 2005. Determination of Rumen Degradability and Ruminal Effects of Three Sources of Methionine in Lactating Cows. J. Dairy Sci. 88, 223–237. https:// doi.org/10.3168/jds.S0022-0302(05)72680-1 13. NRC, 2021. Nutrient Requirements of Dairy Cattle. National Academies Press, Washington, D.C. https://doi.org/10.17226/25806 14. Qin, X., Zhang, D., Qiu, X., Zhao, K., Zhang, S., Liu, C., Lu, L., Cui, Y., Shi, C., Chen, Z., Hao, R., Li, Y., Yang, S., Wang, L., Wang, H., Cao, B., Su, H., 2022. 2-Hydroxy-4-(Methylthio) Butanoic Acid Isopropyl Ester Supplementation Altered Ruminal and Cecal Bacterial Composition and Improved Growth Performance of Finishing Beef Cattle. Front. Nutr. 9, 1–16. https://doi.org/10.3389/fnut.2022.833881 15. Robert, J.-C., Bennett, R., Gros, G., 2000. A method for supplying bioavailable methionine to a cow. WO2000028835A1. 16. St-Pierre, N.R., Sylvester, J.T., 2005. Effects of 2-Hydroxy-4-(Methylthio) Butanoic Acid (HMB) and Its Isopropyl Ester on Milk Production and Composition by Holstein Cows. J. Dairy Sci. 88, 2487–2497. https://doi.org/10.3168/jds.S00220302(05)72926-X
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