ISSUE FOCUS FEED & ADDITIVE MAGAZINE July 2023 25 set stipulating maximum levels of mycotoxins in feed and feed products. By formulating and testing feeds to lower mycotoxin risks and meet the unique needs of different animals, it becomes possible to minimise the adverse effects of mycotoxin co-contamination and ensure optimal health and performance. The list of regulated mycotoxins includes AFB1,2, G1,2, OTA, DON, ZEA, FBs, and T-2/ HT-2 Toxins. Diacetoxyscirpenol (DAS) has been shown to have similar effects as T-2/HT-2 Toxins in animals. Paxilline (PAX), on the other hand, has tremorgenic activity and is a selective and reversible blocker of the smooth muscle high conductance calcium-activated channels. The need to comply with international mycotoxin regulations for feed, and to protect livestock from mycotoxin exposure has necessitated a multi-mycotoxin approach to feed testing. Randox Food Diagnostics Ltd. has developed immunoassay-based Biochip Array Technology (BAT) for the accurate and specific detection of all regulated mycotoxins in a single run. BAT is designed as a mycotoxin detection array and is presented in three formats i.e., Myco 6, Myco 7 and Myco 9 detecting six (6), seven (7) and nine (9) mycotoxins, respectively. The Myco 9 Array is a method which simultaneously and quantitatively detects AFB1,2, G1,2, OTA, DON, ZEA, FBs, T-2/HT-2 Toxins, DAS and PAX in feed and feed products. The Biochip is a ceramic tile on which antibodies, for each of the mycotoxins, are inter-spaced and spotted on predetermined positions [Discrete Test Regions (DTRs)] on the surface. DTRs enable the accurate identification of the different mycotoxins based on the spatial location of each antibody spot. Randox mycotoxin arrays are capable of accurately detecting all regulated mycotoxins i.e., AFBs, OTA, DON, ZEA, FBs, T-2/HT-2 Toxins, PAX and DAS. In the area of multi-mycotoxin determination in feed, LC-MS/MS is the only other platform capable of simultaneous and quantitaTest Menu Ochratoxin A Diacetoxyscirpenol T2/HT2 Toxins Zearalenone Deoxynivalenol Fumonisins Aflatoxin B1 Aflatoxin GI Paxilline Our mycotoxin arrays allow simultaneous detection of up to 9 main groups of mycotoxins from a single sample. info@randoxfood.com randoxfood.com Mycotoxin Arrays Validated in accordance with Commission Decision 2002/657/EC and Commission Regulation (EU) No 519/2014. Export / Import Testing for Feed & Grain
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