SPECIAL STORY 48 FEED & ADDITIVE MAGAZINE March 2023 tivated binding components that can reliably bind all relevant mycotoxins. B.I.O.Tox® Activ8 also contains a phytogenic component consisting of milk thistle and grape seed extracts. With regard to the cytotoxic effects of mycotoxins and the metabolic stress they cause, the polyphenols contained in this phytogenic component can help protect the animals' organism from damage. Furthermore, they offer added value by relieving metabolic pressure, e.g. in the case of oxidative stress. • Increased endotoxin stress can result from a variety of causes. Consequently, a viable solution requires a more conceptual approach. Mycotoxins and endotoxin stress are closely linked. This makes widely effective toxin binders an important part of good endotoxin management. Another mainstay comes from all of the measures and feed additives that positively influence the rumen environment as well as the entire microbiome, this includes selected live yeasts. Various additives that support the dairy cow's liver function and metabolism can also be a valuable component of such a concept. CONCLUSION Modern dairy cows have an outstanding genetic potential that creates the basic prerequisite for an enormous milk yield as well as good fertility. However, the animals can only realize this potential with the support of a suitable environment. Along with good management, feeding, and health, mycotoxins and other negative factors play an important role. The ration formulation for dairy cows comes with a high quantitative and qualitative risk for mycotoxin contamination that exceeds the detoxification capacity of the rumen microbiome. In addition to the harmful effects, mycotoxins closely interact with endotoxin stress as well as with many metabolic diseases. Effective toxin management protects dairy cows from these negative effects. It, therefore, plays a key role in creating ideal production conditions for stable animal health and biological performance.
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