ISSUE FOCUS 56 FEED & ADDITIVE MAGAZINE November 2022 Imagine watching an orchestra: You are interested in the music produced by the musicians together, not what each individual is playing. Recent research suggests that we should look at the microbiome like that orchestra, focusing on what all the microbes are producing together, as a symphony, and how it benefits its animal host. With this idea in mind, and with the development of more advanced technologies in microbiome research, it’s time to change the paradigm: Instead of focusing on which bacteria are present in a microbial community, it’s imperative that we examine what they are doing as a group. In doing this we consider one of the most important characteristics of the microbiome, cooperation, and how microorganisms interact with each other. In the Human Microbiome Project, it became clear that the functions performed by all the bacteria together are far less dependent on the presence or absence of single microbes than previously thought. This functional view of the microbiome provides opportunities to explore what the microorganisms are doing and how the end products of their metabolism benefit the host. Indeed, a large portion of substances in the bloodstream of animals originate from the intestinal microbes, and PRECISE MICROBIOME MODULATION: A NEW ERA IN MICROBIOME RESEARCH IN POULTRY PRODUCTION “A large portion of substances in the bloodstream of animals originate from the intestinal microbes, and these are key when linking physiological processes (e.g., digestion and fermentation) with health and welfare. Modulating the functions of the microbiome by adding nutrients or feed additives brings new opportunities to harness the full potential of the microbiome.” Jack Geremia Global Head of Microbiome Discovery DSM Animal Nutrition Cristiano Bortoluzzi Senior Poultry Scientist – Global Innovation Team DSM Animal Nutrition
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