ISSUE FOCUS 24 FEED & ADDITIVE MAGAZINE August 2022 About Dr. Swamy Haladi, PhD Dr. Haladi is Selko’s Global Programme Manager for the Mycotoxin Risk Management programme. He obtained his Bachelor and Master degrees in veterinary science in India, and then moved to Canada to obtain his PhD in animal and poultry science. During studies and career, he continued to gain more interest and knowledge in the area of mycotoxins, especially the global challenges around this topic. He published various articles in both peer-reviewed journals as well as industry magazines and he truly understands the global challenge of mycotoxins. Furthermore, he developed practical guidance values for mycotoxins in various species. 3.99%. Rumination time saw a reduction as well from 513 to 505 minutes. Additionally, milk yield decreased from 38.29 to 37.55 kg/cow/day (Figure 4). Supplementation of TOXO-XXL at 100 g/cow/ day, however, was able to increase DMI, rumination time and milk yield to 4.09%, 525 minutes and 39.28 kg/cow/day, respectively. CONCLUSIONS • Unlike the perception, dairy cows can succumb to the negative effects of low levels of multiple mycotoxins originating from wide variety of raw materials in TMR. Negative effects can be manifested on their health, milk production, reproductive capacity and milk quality. • Many organs and organ systems are compromised by mycotoxins in dairy cows. Moreover, mycotoxin binding approach alone is not sufficient for the effective management of mycotoxins. It takes combination of mycotoxin binder with ingredients capable of supporting gut, immune system and anti-oxidant system to protect the high-yielding dairy cows. Mycotoxin mitigation methods should be based on the specific objective of feed mills or dairy farms in question. Table 1: Description of treatments for TOXO-XXL trial Description Negative control Positive control Positive control + TOXO-XXL Diet Day 8-62 (intoxication) TMR with minor levels of DON, ZEN and FB, at 284.5, 43.2 and 129.6 ppb, respectively TMR with moderate levels of DON, ZEN and FB, at 1021.0, 196.8 and 238.4 ppb, respectively TMR with moderate levels of DON, ZEN and FB, at 1009.6, 248.5 and 241.7 ppb, respectively and supplemented with 100 g/cow/day TOXO-XXL Treatment 1 (CTR) 2 (MTX) 3 (TOXO-XXL) Day 1-7 (adaptation) TMR with minor levels of DON, ZEN and FB, at 284.5, 43.2 and 129.6 ppb, respectively Figure 4. The efficacy of TOXO-XXL on milk yield; *FCM: fat corrected milk; **ECM: energy corrected milk
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