TRENDING FILE FEED & ADDITIVE MAGAZINE May 2022 51 rhoea reduction and weight gain of weaned piglets. However even after decades of use, there still no consensus on its modes of action. Animine research program ZINCOSUPP (including several theses with renowned European universities) is focusing its effort on understanding every potential hypothesis on the ZnO mode of action (see figure 1, adapted from University of Bologna, Italy). This article will focus on the first phase: correlations between zinc blood concentration, homeostasis and final performance. EFFECTS OF ZnO FED LEVELS ON BLOOD ZINC LEVELS AND HOMEOSTASIS An exhaustive literature review was performed from AniLib scientific database. Out of 151 publications on pharmacological use of ZnO in weaned piglets, 38 were selected as they contained data on blood Zinc concentration at the end of the studies. References of selected papers: 1995 2011, 2013, 2014 2017, 2018 2014, 2020 2012, 2013, 2018 2014 2019 2006 1970, 1993, 1996, 1999, 2001, 2002, 2009, 2013, 2019 2020 1985, 2004 2018 2019 2003, 2005 1998, 2008 2017 2016 Acta Agriculturae Scandinavica Archives of Animal Nutrition Animal Feed Science and Technology Asian Australian JAS Asian Journal of Animal and Veterinary Advances British Journal of Nutrition Canadian JAS Journal of Animal Physiology and Animal Nutrition Journal of Animal Science Journal of Animal Science and Biotechnology Journal of Nutrition Journal of Trace Elements in Medicine and Biology Journal of Veterinary Diagnostic Investigation Journées de la Recherche Porcine KSU Swine Day PlOS one WUR report Figure 1
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