ISSUE FOCUS 20 FEED & ADDITIVE MAGAZINE November 2022 In the search for alternatives to the intensive use of antibiotics in poultry farming, glycerides seem very promising. In a recent trial a combination of glyceride-based additives for feed and drinking water was successful in replacing the preventive use of antibiotics in broilers. Broilers were able to maintain growth performance and health status and even showed an improved immune response. For years feed antibiotics were the number one in combating infections and intestinal disorders that are inevitable in the industrial poultry industry. They significantly improved weight gain, feed conversion and increased safety of the poultry population. However, concerns rise about pathogens becoming resistant to different types of antibiotics and antibacterial therapeutic agents. Therefore, it is of urgent matter to look for new supplements that help optimize animal health and performance and improve the safety and productivity of poultry. KEY ROLE FOR GLYCERIDES In their attempts to produce broiler diets without preventive antibiotics feed manufacturers have been applying conventional organic acids, and later also medium-chain fatty acids, for a long time. Which is not surprising as the mode of action of these acids has long been known and their effectiveness to support growth performance and gut health in broilers is extensively demonstrated in practice. However, new information reveals that the same organic and medium-chain fatty acids can be used much more efficiently. Even more, in the form of 'glycerides' they could play a key role when it comes to replacing preventive antibiotics in poultry farming. How? Let’s take a closer look at these glycerides. WHAT ARE GLYCERIDES? Glycerides are special molecules produced by Adisseo NL (formerly FRAmelco) in which a short or medium chain fatty acid is linked to a glycerol backbone, see Figure 1. The molecule that is created this way has special properties that are very useful to the bird. In contrast to conventional short chain and medium chain fatty acids, glycerides are pH independent and less susceptible to enzymatic breakdown, allowing them to COMBINED APPROACH TO SUCCESSFULLY REPLACE ANTIBIOTICS Joske Schuurmans Global Marketing Manager Adisseo NL B.V. Figure 1. Creating glycerides, like alphamonoglyceride, 1,3-diglyceride and triglyceride.
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